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Arkadia induces degradation of SnoN and c-Ski to enhance transforming growth factor-beta signaling

udgivet i: Journal of Biological Chemistry

dato for udgivelse: 2007-07-13

sprog: engelsk

main subject: SKI proto-oncogene, ubiquitin protein ligase binding, Ring finger 111

Cites articles 54

Date

Titel

Forfattere

2007-03-01

c-Ski activates MyoD in the nucleus of myoblastic cells through suppression of histone deacetylases

Keiji Miyazawa
2006-11-01

Nuclear and cytoplasmic c-Ski differently modulate cellular functions

Shogo Ehata, Keiji Miyazawa
2006-10-30

Dual role of SnoN in mammalian tumorigenesis

Rebecca Berdeaux
2006-12-01

TGFbeta1-induced activation of ATM and p53 mediates apoptosis in a Smad7-dependent manner.

Marene Landström
2006-08-01

Smad7 promotes and enhances skeletal muscle differentiation
2006-11-03

Sumoylated SnoN represses transcription in a promoter-specific manner

Isabelle Pot
2006-03-17

SnoN co-repressor binds and represses smad7 gene promoter
2004-05

New insights into TGF-beta-Smad signalling

Caroline S. Hill
2004-06-01

Down-regulation of Smad7 expression by ubiquitin-dependent degradation contributes to renal fibrosis in obstructive nephropathy in mice

Masatoshi Kitagawa, Kyoko Kitagawa, Chiharu Uchida, Takayuki Hattori, Toshiaki Oda
2004-03-01

Increased expression of c-Ski as a co-repressor in transforming growth factor-beta signaling correlates with progression of esophageal squamous cell carcinoma
2004-05-01

Amplification of SKI is a prognostic marker in early colorectal cancer

Pierluigi Ballabeni
2004-01-29

Endogenous TGF-beta signaling suppresses maturation of osteoblastic mesenchymal cells
2004-02-01

Ski and SnoN: negative regulators of TGF-beta signaling
2004-06-01

c-Ski inhibits the TGF-beta signaling pathway through stabilization of inactive Smad complexes on Smad-binding elements

Mitsuyasu Kato, Keiji Miyazawa
2004-02-01

Systematic interactome mapping and genetic perturbation analysis of a C. elegans TGF-beta signaling network

Patrick J. Hu, Philippe Vaglio, Nicolas Bertin, Mike Boxem, Pierre-Olivier Vidalain, Nono Ayivi-Guedehoussou, Gary Ruvkun, Marc Vidal, Stuart Milstein, Jin Sook Ahn, Muneesh Tewari, Jean Vandenhaute
2004-05-05

Repression of endogenous Smad7 by Ski.
2003-10-01

Smad-dependent and Smad-independent pathways in TGF-beta family signalling

Ying E. Zhang
2003-06-13

Mechanisms of TGF-beta signaling from cell membrane to the nucleus

Joan Massagué Solé, Yigong Shi
2003-03-21

Chromosomal region maintenance 1 (CRM1)-dependent nuclear export of Smad ubiquitin regulatory factor 1 (Smurf1) is essential for negative regulation of transforming growth factor-beta signaling by Smad7

Minoru Yoshida
2003-12-01

Arkadia amplifies TGF-beta superfamily signalling through degradation of Smad7

Keiji Miyazawa
2003-12-17

DAF-5 is a Ski oncoprotein homolog that functions in a neuronal TGF beta pathway to regulate C. elegans dauer development.
2003-05-22

The transforming activity of Ski and SnoN is dependent on their ability to repress the activity of Smad proteins

Sarah Tegen
2002-12-01

Two major Smad pathways in TGF-beta superfamily signalling

Keiji Miyazawa
2002-10-18

Smurf1 regulates the inhibitory activity of Smad7 by targeting Smad7 to the plasma membrane
2002-03-01

Deficient Smad7 expression: a putative molecular defect in scleroderma

Pascal J Goldschmidt-Clermont
2002-11-07

Two short segments of Smad3 are important for specific interaction of Smad3 with c-Ski and SnoN

Keiji Miyazawa
2002-04-19

A system for stable expression of short interfering RNAs in mammalian cells

Reuven Agami, René Bernards
2002-11-01

Structural mechanism of Smad4 recognition by the nuclear oncoprotein Ski: insights on Ski-mediated repression of TGF-beta signaling

Yigong Shi
2001-04-20

Smurf1 interacts with transforming growth factor-beta type I receptor through Smad7 and induces receptor degradation
2001-12-06

Increased susceptibility to tumorigenesis of ski-deficient heterozygous mice
2001-08-24

SNO is a probable target for gene amplification at 3q26 in squamous-cell carcinomas of the esophagus

Issei Imoto
2001-04-12

Induction of the mammalian node requires Arkadia function in the extraembryonic lineages

Daniel C Swan

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