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The intraflagellar transport protein IFT27 promotes BBSome exit from cilia through the GTPase ARL6/BBS3.

著者

David K. Breslow

Maxence V. Nachury

2000 -

Steven P. Gygi

この作品が含まれる作品: Developmental Cell

出版日: 2014-10-30

言語: 英語

main subject: Intraflagellar transport 27, intraciliary transport, Intraflagellar transport 52, Intraflagellar transport 172, Intraflagellar transport 74, Intraflagellar transport 88, Intraflagellar transport 81, TRAF3 interacting protein 1, Intraflagellar transport 20, Intraflagellar transport 57, Intraflagellar transport 22, Intraflagellar transport 46, Intraflagellar transport 80

Cites articles 48

Date

タイトル

著者

2014-09-05

How do cilia organize signalling cascades?

Maxence V. Nachury
2014-06-15

IFT27, encoding a small GTPase component of IFT particles, is mutated in a consanguineous family with Bardet-Biedl syndrome

Fowzan S Alkuraya, Mohammed A Aldahmesh
2014-04-24

The GTPase IFT27 is involved in both anterograde and retrograde intraflagellar transport

Philippe Bastin
2013-02-15

Multiplex genome engineering using CRISPR/Cas systems

Xuebing Wu, Patrick D Hsu
2013-01

Regulation of small GTPases by GEFs, GAPs, and GDIs
2013-12

The roles of evolutionarily conserved functional modules in cilia-related trafficking

Michel R Leroux
2013-01-01

The ciliary G-protein-coupled receptor Gpr161 negatively regulates the Sonic hedgehog pathway via cAMP signaling

Saikat Mukhopadhyay, Suzie J Scales
2013-12-05

A differential cargo-loading model of ciliary length regulation by IFT

Karl Lechtreck
2013-10-07

An in vitro assay for entry into cilia reveals unique properties of the soluble diffusion barrier

David K. Breslow, Maxence V. Nachury
2013-09-11

Exome sequencing of Bardet-Biedl syndrome patient identifies a null mutation in the BBSome subunit BBIP1 (BBS18)

Jean Muller, Maxence V. Nachury, Uwe Strähle, Hélène Dollfus, Elise Schaefer
2013-08-06

Single molecule imaging reveals a major role for diffusion in the exploration of ciliary space by signaling receptors
2013-03-24

A bright monomeric green fluorescent protein derived from Branchiostoma lanceolatum
2012-01-06

BBS proteins interact genetically with the IFT pathway to influence SHH-related phenotypes

Seongjin Seo, Edwin M. Stone, Val C Sheffield
2012-09

The BBSome controls IFT assembly and turnaround in cilia
2012-05-15

IFT25 links the signal-dependent movement of Hedgehog components to intraflagellar transport

Gregory J. Pazour
2011-12-20

Bardet-Biedl syndrome 3 (Bbs3) knockout mouse model reveals common BBS-associated phenotypes and Bbs3 unique phenotypes

Seongjin Seo, Edwin M. Stone, Kamal Rahmouni, Val C Sheffield
2011-11-03

A novel protein LZTFL1 regulates ciliary trafficking of the BBSome and Smoothened

David K. Breslow, Charles C Searby, Seongjin Seo, Maxence V. Nachury, Val C Sheffield
2011-05-18

Crystal structure of the intraflagellar transport complex 25/27

Claire Basquin, Sagar Bhogaraju, Michael Taschner, Esben Lorentzen
2011-05-18

ARF family G proteins and their regulators: roles in membrane transport, development and disease

Catherine L Jackson
2010-06-25

The conserved Bardet-Biedl syndrome proteins assemble a coat that traffics membrane proteins to cilia

Steven P. Gygi
2010

Trafficking to the ciliary membrane: how to get across the periciliary diffusion barrier?
2010-12-09

Dopamine receptor 1 localizes to neuronal cilia in a dynamic process that requires the Bardet-Biedl syndrome proteins
2009

Intraflagellar transport (IFT) protein IFT25 is a phosphoprotein component of IFT complex B and physically interacts with IFT27 in Chlamydomonas
2009-12-01

The Chlamydomonas reinhardtii BBSome is an IFT cargo required for export of specific signaling proteins from flagella

Gregory J. Pazour
2008-12

A BBSome subunit links ciliogenesis, microtubule stability, and acetylation

Charles C Searby, Diane C Slusarski, Maxence V. Nachury, Todd E. Scheetz
2008-03-18

Bardet-Biedl syndrome proteins are required for the localization of G protein-coupled receptors to primary cilia
2008-01-01

Tandem affinity purification of the BBSome, a critical regulator of Rab8 in ciliogenesis

Maxence V. Nachury
2007-06-01

A core complex of BBS proteins cooperates with the GTPase Rab8 to promote ciliary membrane biogenesis

Maxence V. Nachury, Diane C Slusarski, Val C Sheffield
2007-11-30

Structural Basis and Mechanism of Autoregulation in 3-Phosphoinositide-Dependent Grp1 Family Arf GTPase Exchange Factors

Anna Delprato
2007-11

When cilia go bad: cilia defects and ciliopathies
2007-02-01

Intraflagellar transport protein 27 is a small G protein involved in cell-cycle control
2006-03-16

Nucleotide exchange via local protein unfolding--structure of Rab8 in complex with MSS4.

Olena Pylypenko, Aymelt Itzen, Kirill Alexandrov, Roger S. Goody, Alexey Rak

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