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Regulation of 4E-BP1 phosphorylation: a novel two-step mechanism

author

Anne-Claude Gingras

published in: Genes & Development

date of publication: 1999-06-01

language: English

main subject: phosphorylation

Cites articles 55

Date

Title

Authors

1999-06

Cap-dependent translation initiation in eukaryotes is regulated by a molecular mimic of eIF4G
1999-03

Correlation between protein and mRNA abundance in yeast
1999-01-22

Size control in animal development
1999-01-01

eIF4E activity is regulated at multiple levels
1998-11-15

Insulin-stimulated kinase from rat fat cells that phosphorylates initiation factor 4E-binding protein 1 on the rapamycin-insensitive site (serine-111)
1998-06-29

Alpha 4 associates with protein phosphatases 2A, 4, and 6
1998-02-01

RAFT1 phosphorylation of the translational regulators p70 S6 kinase and 4E-BP1

Noam A. Cohen, David M. Sabatini
1998-10-20

Regulation of protein phosphatase 2A catalytic activity by alpha4 protein and its yeast homolog Tap42
1998-09-11

Enhanced phosphorylation of p53 by ATM in response to DNA damage
1998-06-05

Amino acid sufficiency and mTOR regulate p70 S6 kinase and eIF-4E BP1 through a common effector mechanism
1998-02-01

4E-BP1, a repressor of mRNA translation, is phosphorylated and inactivated by the Akt(PKB) signaling pathway

Anne-Claude Gingras, Scott G. Kennedy
1998-12-01

Attenuation of mammalian target of rapamycin activity by increased cAMP in 3T3-L1 adipocytes

Pam Scott
1998-10-01

Inhibition of phosphoinositide 3-kinase related kinases by the radiosensitizing agent wortmannin
1998-06-01

Evidence of insulin-stimulated phosphorylation and activation of the mammalian target of rapamycin mediated by a protein kinase B signaling pathway

Pam Scott
1998-08-01

Amino acid availability regulates p70 S6 kinase and multiple translation factors
1998-07-01

The interaction of eIF4E with 4E-BP1 is an induced fit to a completely disordered protein
1998-05-01

Regulation of translation initiation factors by signal transduction.
1998-05-01

Construction and characterization of a conditionally active version of the serine/threonine kinase Akt.

Morris J. Birnbaum, Pam Scott
1998-04-01

The mRNA 5' cap-binding protein eIF4E and control of cell growth
1998-04-01

Mechanisms and consequences of activation of protein kinase B/Akt

Julian Downward
1998-10-01

Branched-chain amino acids are essential in the regulation of PHAS-I and p70 S6 kinase by pancreatic beta-cells. A possible role in protein translation and mitogenic signaling
1998-11-01

Amino acid effects on translational repressor 4E-BP1 are mediated primarily by L-leucine in isolated adipocytes
1998-01-01

4E binding proteins inhibit the translation factor eIF4E without folded structure

Anne-Claude Gingras
1997-09-01

Structure of translation factor eIF4E bound to m7GDP and interaction with 4E-binding protein

Anne-Claude Gingras
1997-12-19

The mammalian target of rapamycin phosphorylates sites having a (Ser/Thr)-Pro motif and is activated by antibodies to a region near its COOH terminus
1997-04-11

Identification of phosphorylation sites in the translational regulator, PHAS-I, that are controlled by insulin and rapamycin in rat adipocytes
1997-12-26

The structural basis for 14-3-3:phosphopeptide binding specificity
1997-07-04

Phosphorylation of the translational repressor PHAS-I by the mammalian target of rapamycin
1997-01-01

PHAS proteins as mediators of the actions of insulin, growth factors and cAMP on protein synthesis and cell proliferation
1997-09-01

The insulin-induced signalling pathway leading to S6 and initiation factor 4E binding protein 1 phosphorylation bifurcates at a rapamycin-sensitive point immediately upstream of p70s6k
1997-04-01

Responses to DNA damage and regulation of cell cycle checkpoints by the ATM protein kinase family
1997-02-01

PI3K: downstream AKTion blocks apoptosis

Article - wd:Q24603034

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