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Hypoxia-inducible factors and the response to hypoxic stress

published in: Molecular Cell

date of publication: 2010-10-22

language: English

main subject: cell biology, hypoxia

Cites articles 166

Date

Title

Authors

2010-07-01

Siah2-dependent concerted activity of HIF and FoxA2 regulates formation of neuroendocrine phenotype and neuroendocrine prostate tumors

Jianfei Qi, David Bowtell, Zeev Ronai, Robert Cardiff
2010-07-02

Sequencing of 50 human exomes reveals adaptation to high altitude

Jun Wang, Lars Bolund, Karsten Kristiansen, Thorfinn Korneliussen, John E Pool, Ruibang Luo, Rasmus Nielsen, Yang Huanming, Xiuqing Zhang, Qi Yang, Yu Liang, Wei Wang, Ruiqiang Li
2010-06-22

Natural selection on EPAS1 (HIF2alpha) associated with low hemoglobin concentration in Tibetan highlanders

Mark McCormack, Gianpiero L. Cavalleri, Siu Cheung Tam, Cynthia Beall, Michael E. Weale, Jo Knight, Peter A. Robbins, Hugh E Montgomery, Yu Liang, Yaomin Xu, Kevin V Shianna
2010-02-18

The common feature of leukemia-associated IDH1 and IDH2 mutations is a neomorphic enzyme activity converting alpha-ketoglutarate to 2-hydroxyglutarate

Patrick S. Ward, David R Wise, Omar Abdel-Wahab, Justin R. Cross, Cyrus V Hedvat
2010-05-13

Genetic evidence for high-altitude adaptation in Tibet

Jinchuan Xing, Lynn Jorde, Chad D. Huff, Tatum S Simonson, Josef T Prchal
2010-01-01

The histone deacetylase Sirt6 regulates glucose homeostasis via Hif1alpha

Carlos Sebastian, Jakob D Wikstrom, Ralph Weissleder, Joaquín M Espinosa, Leif W Ellisen
2010

Mammalian sirtuins: biological insights and disease relevance
2010-07-21

HIF-2alpha deletion promotes Kras-driven lung tumor development.

Tyler Jacks
2010-07-19

Hypoxia-inducible factor 2alpha regulates macrophage function in mouse models of acute and tumor inflammation
2010-07-01

Negative regulation of hypoxic responses via induced Reptin methylation

Olivier Binda, Or Gozani, Gregg L. Semenza
2010-06-01

HIF-1 antagonizes p53-mediated apoptosis through a secreted neuronal tyrosinase

Christof Fellmann, Michael Otmar Hengartner
2010-05-10

COMMD1 disrupts HIF-1alpha/beta dimerization and inhibits human tumor cell invasion

Cisca Wijmenga, Ezra Burstein
2010-04-28

Knockout of HIF-1α in tumor-associated macrophages enhances M2 polarization and attenuates their pro-angiogenic responses

Bernhard Brüne, Nathalie Dehne, Andreas Weigert, Heidi Menrad, Christian Werno
2010-04-15

The asparaginyl hydroxylase factor inhibiting HIF-1alpha is an essential regulator of metabolism

DeeAnn W Visk, Daniel J. Peet, Randall S. Johnson
2010-04-01

ERbeta impedes prostate cancer EMT by destabilizing HIF-1alpha and inhibiting VEGF-mediated snail nuclear localization: implications for Gleason grading
2010-03-22

P53-induced microRNA-107 inhibits HIF-1 and tumor angiogenesis

Ralph H. Hruban
2010-03-15

Imatinib resistance associated with BCR-ABL upregulation is dependent on HIF-1alpha-induced metabolic reprograming
2010-03-01

Differential activation and antagonistic function of HIF-{alpha} isoforms in macrophages are essential for NO homeostasis
2010-01-11

Digoxin inhibits retinal ischemia-induced HIF-1alpha expression and ocular neovascularization

Gregg L. Semenza
2010-02-08

Cancer-associated metabolite 2-hydroxyglutarate accumulates in acute myelogenous leukemia with isocitrate dehydrogenase 1 and 2 mutations
2010-06-25

Sirtuin 1 modulates cellular responses to hypoxia by deacetylating hypoxia-inducible factor 1alpha
2010-10-22

Regulation of the mTOR complex 1 pathway by nutrients, growth factors, and stress
2010-10-01

Translational regulation of gene expression during conditions of cell stress
2010-10-01

Protein quality control in the cytosol and the endoplasmic reticulum: brothers in arms

Alexander Buchberger, Bernd Bukau
2009-12-01

Cancer-associated IDH1 mutations produce 2-hydroxyglutarate

Robert M. Prins, Patrick S. Ward, Linda Liau, Lewis C. Cantley
2009-09-01

Hypoxia-inducible mir-210 regulates normoxic gene expression involved in tumor initiation

Scott M Welford, Amato J. Giaccia, Kie-Kian Ang
2009-06-01

MYPT1, the targeting subunit of smooth-muscle myosin phosphatase, is a substrate for the asparaginyl hydroxylase factor inhibiting hypoxia-inducible factor (FIH)

Mathew L Coleman, Peter J. Ratcliffe, Christopher J A Pugh
2009-02-10

Erythrocytosis-associated HIF-2alpha mutations demonstrate a critical role for residues C-terminal to the hydroxylacceptor proline

Frank S. Lee, Mary Frances McMullin
2009-01-06

Hypoxia-induced lysyl oxidase is a critical mediator of bone marrow cell recruitment to form the premetastatic niche

Janine Terra Erler, Thomas R Cox, Albert C. Koong, Amato J. Giaccia
2009-04-01

Glioma-derived mutations in IDH1 dominantly inhibit IDH1 catalytic activity and induce HIF-1alpha

Qun-Ying Lei
2009-12-17

Hypoxia triggers subcellular compartmental redox signaling in vascular smooth muscle cells
2009-12-02

Human cancers converge at the HIF-2alpha oncogenic axis

Chet E Holterman

Article - wd:Q24629323

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