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Mammalian ceramide synthases

author

Anthony H. Futerman

publicado em: IUBMB Life

date of publication: 2010-05

language: inglês

main subject: biologia celular, Ceramida

Cites articles 81

Date

Title

Authors

2010-04-02

A critical role for ceramide synthase 2 in liver homeostasis: II. insights into molecular changes leading to hepatopathy

Shifra Ben-Dor, Anthony H. Futerman
2010-01-01

Stress-induced ER to Golgi translocation of ceramide synthase 1 is dependent on proteasomal processing

Junxia Min, Anthony H. Futerman
2010-01-28

A critical role for ceramide synthase 2 in liver homeostasis: I. alterations in lipid metabolic pathways

Johnny Stiban, Liana C. Silva, Manuel Prieto, Anthony H. Futerman
2009-01-01

Central leptin regulates total ceramide content and sterol regulatory element binding protein-1C proteolytic maturation in rat white adipose tissue
2009-11-11

Increased ceramide synthase 2 and 6 mRNA levels in breast cancer tissues and correlation with sphingosine kinase expression

Anthony H. Futerman
2009-09-30

Adult ceramide synthase 2 (CERS2)-deficient mice exhibit myelin sheath defects, cerebellar degeneration, and hepatocarcinomas
2009-11-11

Disruption of ceramide synthesis by CerS2 down-regulation leads to autophagy and the unfolded protein response

Lina M. Obeid, Danyelle M Townsend
2009-09-01

Antiapoptotic roles of ceramide-synthase-6-generated C16-ceramide via selective regulation of the ATF6/CHOP arm of ER-stress-response pathways

Yusuf A. Hannun
2009-07-01

Potentiation of cannabinoid-induced cytotoxicity in mantle cell lymphoma through modulation of ceramide metabolism
2009-05-29

Sorafenib and vorinostat kill colon cancer cells by CD95-dependent and -independent mechanisms

Paul Dent
2009-04-08

Ceramide synthesis is modulated by the sphingosine analog FTY720 via a mixture of uncompetitive and noncompetitive inhibition in an Acyl-CoA chain length-dependent manner

Anthony H. Futerman
2009-03-11

Ceramide synthases and ceramide levels are increased in breast cancer tissue

Susanne Schiffmann, Jörn Lötsch
2009-04-22

Ceramide synthase 1 is regulated by proteasomal mediated turnover

Anthony H. Futerman
2009-01-12

Ceramide synthase 6 modulates TRAIL sensitivity and nuclear translocation of active caspase-3 in colon cancer cells

Lina M. Obeid
2008

Roles of bioactive sphingolipids in cancer biology and therapeutics
2008-08-01

Ceramide generated by sphingomyelin hydrolysis and the salvage pathway is involved in hypoxia/reoxygenation-induced Bax redistribution to mitochondria in NT-2 cells

Junfei Jin, Lina M. Obeid, Yusuf A. Hannun
2008-11

2-Hydroxy-ceramide synthesis by ceramide synthase family: enzymatic basis for the preference of FA chain length

Akio Kihara
2008-05-09

Male germ cells require polyenoic sphingolipids with complex glycosylation for completion of meiosis: a link to ceramide synthase-3

Hermann-Josef Gröne, Frances Platt
2008-07-30

Global organization of replication time zones of the mouse genome

Itamar Simon, Alon Goren
2008-03-04

De novo N-palmitoylsphingosine synthesis is the major biochemical mechanism of ceramide accumulation following p53 up-regulation

Lina M. Obeid, Yusuf A. Hannun
2008-03-01

Long-chain ceramide is elevated in presenilin 1 (PS1M146V) mouse brain and induces apoptosis in PS1 astrocytes
2007-08

(Dihydro)ceramide synthase 1 regulated sensitivity to cisplatin is associated with the activation of p38 mitogen-activated protein kinase and is abrogated by sphingosine kinase 1

Junxia Min, Mayandi Sivaguru, Anthony H. Futerman
2007-12-28

Characterization of ceramide synthase 2: tissue distribution, substrate specificity, and inhibition by sphingosine 1-phosphate

Anthony H. Futerman
2007-10-23

Kinetic characterization of mammalian ceramide synthases: determination of K(m) values towards sphinganine

Anthony H. Futerman, Adriana Haimovitz-Friedman
2007-09-28

Differential expression of (dihydro)ceramide synthases in mouse brain: oligodendrocyte-specific expression of CerS2/Lass2.
2007-07-09

Clinical relevance of ceramide metabolism in the pathogenesis of human head and neck squamous cell carcinoma (HNSCC): attenuation of C(18)-ceramide in HNSCC tumors correlates with lymphovascular invasion and nodal metastasis

Yusuf A. Hannun
2007-02-01

Role of human longevity assurance gene 1 and C18-ceramide in chemotherapy-induced cell death in human head and neck squamous cell carcinomas

Yusuf A. Hannun
2007-01-22

Large-scale phosphorylation analysis of mouse liver

Judit Villén, Scott A. Gerber, Sean A Beausoleil, Steven P. Gygi
2007-01-01

Yeast sphingolipids do not need to contain very long chain fatty acids
2007-12-04

Microarray analysis of altered sphingolipid metabolism reveals prognostic significance of sphingosine kinase 1 in breast cancer

Thomas Karn, Gunter von Minckwitz, Susanne Schiffmann
2007-07-03

JNK3 signaling pathway activates ceramide synthase leading to mitochondrial dysfunction.
2007-02-15

Alterations of ceramide/sphingosine 1-phosphate rheostat involved in the regulation of resistance to imatinib-induced apoptosis in K562 human chronic myeloid leukemia cells

Lina M. Obeid

Article - wd:Q24633453

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