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The Drosophila forkhead transcription factor FOXO mediates the reduction in cell number associated with reduced insulin signaling

author

Thomas Radimerski

Jonathan D. Wasserman

published in: Journal of Biology

date of publication: 2003

language: English

main subject: Drosophila, Forkhead box, sub-group O Dmel_CG3143, preproinsulin

Cites articles 75

Date

Title

Authors

2003-07-05

Expression of Drosophila FOXO regulates growth and can phenocopy starvation
2003-06

Insulin activation of Rheb, a mediator of mTOR/S6K/4E-BP signaling, is inhibited by TSC1 and 2
2003-06

Rheb is a direct target of the tuberous sclerosis tumour suppressor proteins
2003-07-31

Control of cell number by Drosophila FOXO: downstream and feedback regulation of the insulin receptor pathway

Robert Tjian
2003-06-01

Rheb promotes cell growth as a component of the insulin/TOR signalling network
2003-06-01

Rheb is an essential regulator of S6K in controlling cell growth in Drosophila
2002-05-31

The phosphoinositide 3-kinase pathway

Lewis C. Cantley
2002-09

TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signalling
2002-07-01

Cell cycle and death control: long live Forkheads

Geert Kops
2002-07-26

FOXO forkhead transcription factors induce G(2)-M checkpoint in response to oxidative stress
2002-04-01

DNA repair pathway stimulated by the forkhead transcription factor FOXO3a through the Gadd45 protein

Albert J Fornace
2002-12-04

IGF-1 receptor regulates lifespan and resistance to oxidative stress in mice

Martin Holzenberger, Bertrand Ducos, Patrick Even, Joëlle Dupont, Patricia Leneuve, Pascale Cervera, Yves Le Bouc
2002-09-01

Forkhead transcription factor FOXO3a protects quiescent cells from oxidative stress

Geert Kops, René H. Medema
2002-09-01

Akt regulates growth by directly phosphorylating Tsc2

Christopher J. Potter
2002-11-01

Nutrient control of gene expression in Drosophila: microarray analysis of starvation and sugar-dependent response
2002-11-01

Cell cycle inhibition by FoxO forkhead transcription factors involves downregulation of cyclin D

René H. Medema, Marc Schmidt, Silvia Fernández de Mattos, Geert Kops, Eric W-F Lam
2002-10-01

Lethality of Drosophila lacking TSC tumor suppressor function rescued by reducing dS6K signaling
2002-09-03

Regulation of insulin action and pancreatic beta-cell function by mutated alleles of the gene encoding forkhead transcription factor Foxo1.

Domenico Accili
2002-09-01

Tsc tumour suppressor proteins antagonize amino-acid-TOR signalling
2002-07-01

A novel mechanism of gene regulation and tumor suppression by the transcription factor FKHR.
2002-06-01

Eiger, a TNF superfamily ligand that triggers the Drosophila JNK pathway
2002-03-01

Mechanisms of ageing: public or private?

Linda Partridge, David Gems
2002-02-28

Living with lethal PIP3 levels: viability of flies lacking PTEN restored by a PH domain mutation in Akt/PKB,Living with Lethal PIP3 Levels: Viability of Flies Lacking PTEN Restored by a PH Domain Mutation in Akt/PKB

Muriel Laffargue, Matthias P Wymann
2002-01-28

FKHR-L1 can act as a critical effector of cell death induced by cytokine withdrawal: protein kinase B-enhanced cell survival through maintenance of mitochondrial integrity

Eric W-F Lam, Leo Koenderman
2002-11-01

Adaptive responses to oxidative damage in three mutants of Caenorhabditis elegans (age-1, mev-1 and daf-16) that affect life span
2002-09-01

The Drosophila insulin/IGF receptor controls growth and size by modulating PtdInsP(3) levels.

Matthias P Wymann
2002-06-01

Paraquat detoxicative system in the mouse liver postmitochondrial fraction
2002-03-01

dS6K-regulated cell growth is dPKB/dPI(3)K-independent, but requires dPDK1.
2001-02

Protein kinase SGK mediates survival signals by phosphorylating the forkhead transcription factor FKHRL1 (FOXO3a)

Brian Hemmings
2001-05-22

Solution structure of the DNA binding domain of the human forkhead transcription factor AFX (FOXO4)

Karin Dahlman-Wright
2001-04-06

Extension of life-span by loss of CHICO, a Drosophila insulin receptor substrate protein
2001-04-06

A mutant Drosophila insulin receptor homolog that extends life-span and impairs neuroendocrine function

Article - wd:Q24794823

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