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The epidermal growth factor receptor variant III (EGFRvIII): where wild things are altered

この作品が含まれる作品: FEBS Journal

出版日: 2013-11

言語: 英語

Cites articles 179

Date

タイトル

著者

2013-01-01

Regulation of HGF expression by ΔEGFR-mediated c-Met activation in glioblastoma cells

Kristen S Hill, Oliver Bogler
2012-02-07

Glioblastoma stem-like cell lines with either maintenance or loss of high-level EGFR amplification, generated via modulation of ligand concentration

Alexander Schulte
2012-02-07

Phosphorylation of dedicator of cytokinesis 1 (Dock180) at tyrosine residue Y722 by Src family kinases mediates EGFRvIII-driven glioblastoma tumorigenesis

Tim R Fenton, Frank B Furnari, Terrance G Johns
2012-12-17

Systemic administration of a bispecific antibody targeting EGFRvIII successfully treats intracerebral glioma

Patrick C Gedeon, John Sampson
2012-03

In situ analysis of mutant EGFRs prevalent in glioblastoma multiforme reveals aberrant dimerization, activation, and differential response to anti-EGFR targeted therapy
2012-06-01

Targeting of a conformationally exposed, tumor-specific epitope of EGFR as a strategy for cancer therapy
2011-09-13

Oncogenic EGFR signaling activates an mTORC2-NF-κB pathway that promotes chemotherapy resistance

Harry V Vinters, Timothy F. Cloughesy
2011-09-01

Activation of Src induces mitochondrial localisation of de2-7EGFR (EGFRvIII) in glioma cells: implications for glucose metabolism

Amelia J Johnston, Anna N Cvrljevic, Frank B Furnari, Terrance G Johns, Andrew M Scott
2011-12-05

EGFRvIII promotes glioma angiogenesis and growth through the NF-κB, interleukin-8 pathway

Frank B Furnari
2011-04-18

Glioma Specific Extracellular Missense Mutations in the First Cysteine Rich Region of Epidermal Growth Factor Receptor (EGFR) Initiate Ligand Independent Activation

Sameer A Greenall, Anna N Cvrljevic, Jacqueline F Donoghue, Andrew M Scott, Timothy E Adams, Terrance G Johns
2011-07-20

Forced dimerization increases the activity of ΔEGFR/EGFRvIII and enhances its oncogenicity

Oliver Bogler
2011-10-11

Cetuximab induces mitochondrial translocalization of EGFRvIII, but not EGFR: involvement of mitochondria in tumor drug resistance?

Stefan Barth
2010-08-29

Glioblastoma-derived spheroid cultures as an experimental model for analysis of EGFR anomalies

Piotr Rieske, Magdalena Zakrzewska, Robert Stawski, Michał Bieńkowski, Ewelina Stoczynska-Fidelus, Dariusz J Jaskólski, James Ironside, Paweł P. Liberski, Dominika Kulczycka-Wojdala, Monika Witusik-Perkowska, Sylwester Piaskowski
2010-07-16

MAb 806 enhances the efficacy of ionizing radiation in glioma xenografts expressing the de2-7 epidermal growth factor receptor

Anna N Cvrljevic, Terrance G Johns, Andrew M Scott
2010-08-01

Tumor heterogeneity is an active process maintained by a mutant EGFR-induced cytokine circuit in glioblastoma

Cameron Brennan, Frank B Furnari, Terrance G Johns, Ronald A. DePinho
2010-10-04

Immunologic escape after prolonged progression-free survival with epidermal growth factor receptor variant III peptide vaccination in patients with newly diagnosed glioblastoma

Henry Seth Friedman, Darell D. Bigner, Allan Friedman, David A Reardon, Roger E McLendon, James J Vredenburgh, James H. Herndon, Robert J Schmittling, Duane A Mitchell, Kenneth D Aldape, Raymond Sawaya, Weiming Shi
2009-02-01

Improved response by co-targeting EGFR/EGFRvIII and Src family kinases in human cancer cells

Peter Andersen
2009-04-23

Genetically engineered T cells to target EGFRvIII expressing glioblastoma

Ralph Weissleder
2009-04-22

Pro-survival AKT and ERK signaling from EGFR and mutant EGFRvIII enhances DNA double-strand break repair in human glioma cells
2009-07-22

The AMPK agonist AICAR inhibits the growth of EGFRvIII-expressing glioblastomas by inhibiting lipogenesis

Caius Radu, Robert M. Prins, Timothy F. Cloughesy
2009-03-01

Mutant epidermal growth factor receptor vIII increases cell motility and clonogenecity in a prostate cell line RWPE1.
2009-02-01

Labeling internalizing anti-epidermal growth factor receptor variant III monoclonal antibody with (177)Lu: in vitro comparison of acyclic and macrocyclic ligands
2009-01-27

Vasculostatin inhibits intracranial glioma growth and negatively regulates in vivo angiogenesis through a CD36-dependent mechanism

Erwin G. Van Meir
2009-08-18

Fyn and SRC are effectors of oncogenic epidermal growth factor receptor signaling in glioblastoma patients

Anna N Cvrljevic, Frank B Furnari, Thomas Graeber, Terrance G Johns, Timothy F. Cloughesy, Gabriele Bergers, Stanley F Nelson
2009-05-12

EGFRvIII and DNA double-strand break repair: a molecular mechanism for radioresistance in glioblastoma

Cristel V Camacho, Frank B Furnari
2009-05-01

The plasticity of oncogene addiction: implications for targeted therapies directed to receptor tyrosine kinases

Terrance G Johns, Andrew M Scott
2009-03-10

Epidermal growth factor receptor and PTEN modulate tissue factor expression in glioblastoma through JunD/activator protein-1 transcriptional activity

Erwin G. Van Meir
2009-02-12

Epidermal growth factor receptor vIII enhances tumorigenicity and resistance to 5-fluorouracil in human hepatocellular carcinoma
2009-06-09

Demonstration of the equivalent pharmacokinetic/pharmacodynamic dosing strategy in a multiple-dose study of gefitinib
2009-03-27

Boron neutron capture therapy of EGFR or EGFRvIII positive gliomas using either boronated monoclonal antibodies or epidermal growth factor as molecular targeting agents
2009-05-08

The protein tyrosine phosphatase SHP-2 is required for EGFRvIII oncogenic transformation in human glioblastoma cells

Donald M O'Rourke
2009-11-01

EGFRvIII-induced estrogen-independence, tamoxifen-resistance phenotype correlates with PgR expression and modulation of apoptotic molecules in breast cancer

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