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The enemy within: endogenous retroelements and autoimmune disease

এতে প্রকাশিত: Nature Immunology

তারিখে প্রকাশিত: 2014-05

ভাষা: ইংরেজি ভাষা

মূল বিষয়: স্বতঃঅনাক্রম্য রোগ

Cites articles 97

তারিখ

শিরোনাম

লেখকগণ

2014-01-23

Cell death by pyroptosis drives CD4 T-cell depletion in HIV-1 infection
2014-01-24

IFI16 DNA sensor is required for death of lymphoid CD4 T cells abortively infected with HIV

Nevan Krogan
2014-02-13

The Cytosolic DNA Sensor cGAS Forms an Oligomeric Complex with DNA and Undergoes Switch-like Conformational Changes in the Activation Loop

Jiaxi Wu, Chad A Brautigam, Zhijian Chen
2014-01-20

SAMHD1 prevents autoimmunity by maintaining genome stability

Andreas Dahl, Alexander Rapp, Jochen Guck, Min Ae Lee-Kirsch
2014-01-01

Therapies in Aicardi-Goutières syndrome

Yanick J. Crow, Adeline Vanderver, Simona Orcesi, Gillian I. Rice
2014-02-13

Autoimmune disorders associated with gain of function of the intracellular sensor MDA5

Sadayoshi Itō
2013-11-13

Human cytomegalovirus tegument protein pUL83 inhibits IFI16-mediated DNA sensing for immune evasion
2013-05-01

Cytosolic sensing of viruses

Caetano Reis e Sousa
2013-11-21

HIV-1 evades innate immune recognition through specific cofactor recruitment

Amanda J. Price, David A. Jacques, David L Selwood, Mahdad Noursadeghi, Gregory Towers
2013-06-20

Structural mechanism of cytosolic DNA sensing by cGAS

Karl-Peter Hopfner, Veit Hornung, Gregor Witte
2013-05-30

Structure of Human cGAS Reveals a Conserved Family of Second-Messenger Enzymes in Innate Immunity

জেনিফার ডাউডনা, Philip J Kranzusch, James M. Berger
2013-05-23

Cyclic [G(2′,5′)pA(3′,5′)p] Is the Metazoan Second Messenger Produced by DNA-Activated Cyclic GMP-AMP Synthase

Thomas Tuschl, Dinshaw J. Patel, Winfried Barchet, Gunther Hartmann, Manuel Ascano
2013-02-15

Cyclic GMP-AMP is an endogenous second messenger in innate immune signaling by cytosolic DNA

Jiaxi Wu, Chuo Chen, Zhijian J Chen
2013-12-12

SAMHD1 is mutated recurrently in chronic lymphocytic leukemia and is involved in response to DNA damage

অ্যাডাম বার্নস, Philippe Pasero, Jonathan Maelfait, Jan Rehwinkel, Samantha J.L. Knight, Jenny Taylor, Yanick J. Crow, Amalio Telenti
2013-11-21

The capsids of HIV-1 and HIV-2 determine immune detection of the viral cDNA by the innate sensor cGAS in dendritic cells

Matteo Gentili, Christine Lacabaratz, Jean-Daniel Lelievre, Nicolas Manel
2013-11-06

Adenovirus detection by the cGAS/STING/TBK1 DNA sensing cascade

Saskia C Stein
2013-10-23

IFI16 senses DNA forms of the lentiviral replication cycle and controls HIV-1 replication

Rasmus O. Bak, Lars Østergaard, Tsan Sam Xiao, Jacob Giehm Mikkelsen, Søren Riis Paludan
2013-08-29

Pivotal roles of cGAS-cGAMP signaling in antiviral defense and immune adjuvant effects

Zhijian J Chen
2013-08-22

Mouse SAMHD1 has antiretroviral activity and suppresses a spontaneous cell-intrinsic antiviral response

Andreas Dahl, Kathrin Gibbert, Stefan Lienenklaus, Dirk Lindemann, Werner Müller, Rayk Behrendt, Ulf Dittmer
2013-07-29

The interferon response to intracellular DNA: why so many receptors?

Leonie Unterholzner
2013-08-08

Cyclic GMP-AMP synthase is an innate immune sensor of HIV and other retroviruses

Jiaxi Wu, Zhijian J Chen
2013-07-19

SAMHD1-dependent retroviral control and escape in mice

Yanick J. Crow, Caetano Reis e Sousa, Jan Rehwinkel, Jonathan Maelfait, Anne M Bridgeman, Rachel E Rigby, Gregory Towers, Luís F. Moita, David T. Bonthron, Paul Bieniasz
2013-07-01

The cGAS-STING pathway for DNA sensing
2013-05-30

cGAS produces a 2'-5'-linked cyclic dinucleotide second messenger that activates STING.

Karl-Peter Hopfner, Ingo Röhl, Veit Hornung
2013-05-23

The innate immune DNA sensor cGAS produces a noncanonical cyclic dinucleotide that activates human STING

Mamoru Hyodo
2012-12-20

Cyclic GMP-AMP synthase is a cytosolic DNA sensor that activates the type I interferon pathway

Jiaxi Wu, Zhijian J Chen
2012

SAMHD1 restricts HIV-1 reverse transcription in quiescent CD4(+) T-cells

Gillian I. Rice, Olivier Schwartz, Yanick J. Crow
2012-04-20

Structures of the HIN Domain:DNA Complexes Reveal Ligand Binding and Activation Mechanisms of the AIM2 Inflammasome and IFI16 Receptor

Veit Hornung, Eicke Latz, Leonie Unterholzner, Gabor L Horvath, Jiansheng Jiang, Tengchuan Jin, Andrew G Bowie, Ricky W Johnstone
2012-11

Mutations in ADAR1 cause Aicardi-Goutières syndrome associated with a type I interferon signature

Paul Kasher, Elizabeth Whittaker, Tracy Briggs, ম্যারি এ ও'কনেল, Gillian I. Rice, Simon C Lovell, Adeline Vanderver, Elisa Fazzi, Jean-Pierre Lin, Yanick J. Crow, Roberta Battini, Enrico Bertini, Tiong Y Tan, Arvid Heiberg, Carlos A Bacino, Corinne De Laet, Àngels García-Cazorla, Magnhild Rasmussen, Evangeline Wassmer, Isabelle Desguerre, Pascale de Lonlay, William G van der Merwe, Simona Orcesi, Emma Wakeling, Gabriella M A Forte, Marcin Szynkiewicz, Ivana Olivieri, Flore Rozenberg, Grace Vassallo
2012-07-16

Mammalian RNase H2 removes ribonucleotides from DNA to maintain genome integrity

Martin Achleitner, Rayk Behrendt
2012-05-01

Human transposon tectonics

Jef D Boeke
2012-01-01

Rules of engagement: molecular insights from host-virus arms races

Harmit Singh Malik

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