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CNVs: harbingers of a rare variant revolution in psychiatric genetics

author

Jonathan Sebat

published in: Cell

date of publication: 2012-03-16

language: English

Cites articles 143

Date

Title

Authors

2012-02-01

Genome-wide analysis of copy number variants in attention deficit hyperactivity disorder: the role of rare variants and duplications at 15q13.3.

Barbara Franke, Michael Gill, Michael C O'Donovan, Stephen Faraone, Hans-Christoph Steinhausen, Nanda Rommelse, Kate Langley, Ziarih Hawi, Lindsey Kent, Susanne Walitza, Herbert Roeyers, Eric Mick, Russell Schachar, Anita Thapar, Peter Holmans, Philip Asherson, Klaus-Peter Lesch, Jan Buitelaar, Stephen W. Scherer, Joseph Biederman, Richard Anney, Frank A Middleton, Hakon Hakonarson, Susan Smalley, Nguyen Thi Thuy Trang, Andreas Reif, Tobias Renner, Jasmin Romanos, Christine M Freitag, Jobst Meyer, Sandra K Loo, Alejandro Arias-Vásquez, Christian Marshall, Alexandre A Todorov, Andreas Warnke, Anath C. Lionel, Stanley F Nelson, Jennifer Crosbie, Corina J Shtir, Christiane Seitz, Marcel Romanos, Joseph A Sergeant
2011-07

Variation in genome-wide mutation rates within and between human families

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2011-04-13

Modelling schizophrenia using human induced pluripotent stem cells

Jonathan Sebat, Kristen J. Brennand, Fred Gage
2011-03-20

Shank3 mutant mice display autistic-like behaviours and striatal dysfunction

João Peça, Catia Feliciano, Jonathan T Ting, Wenting Wang
2011-02-03

Mapping copy number variation by population-scale genome sequencing

Jun Wang, Fereydoun Hormozdiari, Evan E. Eichler, Zamin Iqbal, Alexej Abyzov, Klaudia Walter, Jeffrey M. Kidd, Lilia M. Iakoucheva, Jan Korbel, Jonathan Sebat, Can Alkan, Deniz Kural, Ryan E. Mills, Tobias Rausch, Ruibang Luo, Mark Bender Gerstein, Mark Batzer, Michael P. Snyder, Andreas Dahl, Andrew G. Clark, Asif T. Chinwalla, Chip Stewart, Ruiqiang Li, Heather E Peckham, Robert E Handsaker, Miriam K Konkel, Xinmeng Jasmine Mu, Adrian M Stütz, Jerilyn A Walker, Gabor T Marth, Steven A McCarroll, Seungtai Chris Yoon, R Keira Cheetham, Donald F Conrad, Yutao Fu, Fabian Grubert, Iman Hajirasouliha, Shuli Kang, Joshua M Korn, Ekta Khurana, Chang-Yun Lin, James Nemesh, Aylwyn Scally, Michael P Stromberg, Alexander Eckehart Urban, Matthew Hurles, Gilean McVean
2011-12-04

Genome-wide copy number variation study associates metabotropic glutamate receptor gene networks with attention deficit hyperactivity disorder

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2011-01-01

LINE-1 elements in structural variation and disease

Jose Luis Garcia-Perez, Richard Badge
2011-11-01

Genetic Heritability and Shared Environmental Factors Among Twin Pairs With Autism
2011-06-01

Multiple recurrent de novo CNVs, including duplications of the 7q11.23 Williams syndrome region, are strongly associated with autism

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Rare De Novo and Transmitted Copy-Number Variation in Autistic Spectrum Disorders

Michael Wigler, Michael Ronemus, Abba M. Krieger, Ivan Iossifov, Anthony Leotta, Jude Kendall, Jennifer Troge, Linda H Rodgers
2011-09-01

Absence of CNTNAP2 leads to epilepsy, neuronal migration abnormalities, and core autism-related deficits

Olga Peñagarikano, Elior Peles, Daniel Geschwind
2011-08-14

A copy number variation morbidity map of developmental delay
2011-05-15

Exome sequencing in sporadic autism spectrum disorders identifies severe de novo mutations

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2011-12-01

High frequencies of de novo CNVs in bipolar disorder and schizophrenia

Michael Gill, Francis J. McMahon, Marcella Rietschel, Vladimir Vacic, Jonathan Sebat, Aiden Corvin, Sven Cichon, Markus M Nöthen, Jacob J Michaelson, Katherine E Burdick, Thomas G. Schulze, James B Potash, Deborah M Levy, John R Kelsoe, Elliot S Gershon, Dheeraj Malhotra, Shane McCarthy, Olga Krastoshevsky, Verena Krause, Sydney Gary
2011-11-27

Using iPSC-derived neurons to uncover cellular phenotypes associated with Timothy syndrome

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2011-11-15

De novo CNV analysis implicates specific abnormalities of postsynaptic signalling complexes in the pathogenesis of schizophrenia

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2011-10-30

The conundrums of understanding genetic risks for autism spectrum disorders
2011-10-12

Functional enrichment analysis with structural variants: pitfalls and strategies
2011-10-01

Frequency of nonallelic homologous recombination is correlated with length of homology: evidence that ectopic synapsis precedes ectopic crossing-over

Feng Zhang, James R. Lupski
2011-10-03

Dosage-dependent phenotypes in models of 16p11.2 lesions found in autism

Michael Wigler, Jason Lerch, Abba M. Krieger
2011-10-02

Inverted genomic segments and complex triplication rearrangements are mediated by inverted repeats in the human genome

Claudia Gonzaga-Jauregui, John W. Belmont, Davut Pehlivan, Huda Zoghbi, James R. Lupski, Sau Wai Cheung, Melissa B Ramocki
2011-09-01

Chromosome catastrophes involve replication mechanisms generating complex genomic rearrangements

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2011-08-31

Mirror extreme BMI phenotypes associated with gene dosage at the chromosome 16p11.2 locus

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2011-08-07

Exome sequencing supports a de novo mutational paradigm for schizophrenia

Johannes Roos, Phillip Dexheimer, Shawn Levy, Joseph A Gogos
2011-06-01

The human brain in a dish: the promise of iPSC-derived neurons

Daniel Geschwind, Ricardo E Dolmetsch
2011-06-01

Rare de novo variants associated with autism implicate a large functional network of genes involved in formation and function of synapses

Michael Wigler, Michael Ronemus, Ivan Iossifov
2011-04-13

Genome-wide analysis shows increased frequency of copy number variation deletions in Dutch schizophrenia patients

Hreinn Stefansson, Richard Bruggeman
2011-03-03

Isolation of MECP2-null Rett Syndrome patient hiPS cells and isogenic controls through X-chromosome inactivation

James Ellis, Akitsu Hotta
2011-03-01

Genome structural variation discovery and genotyping

Can Alkan, Evan E. Eichler
2011-04-01

Autism spectrum disorders--a genetics review
2011-02-23

Duplications of the neuropeptide receptor gene VIPR2 confer significant risk for schizophrenia.

Michael Gill, Mary-Claire King, Vladimir Vacic, Lilia M. Iakoucheva, Jonathan Sebat, Derek W. Morris, Aiden Corvin, Fiona Murray, Deborah M Levy, John R Kelsoe, Elliot S Gershon, Dheeraj Malhotra, Shane McCarthy, Jon Mcclellan, Olga Krastoshevsky, Verena Krause, Hsun-Hua Chou, Roser Corominas, Verónica Larach-Walters, Marie L Dell' Aquila
2011-01-05

Analysis of genetic deletions and duplications in the University College London bipolar disorder case control sample

Jennifer L. Moran, Andrew McQuillin, Pamela Sklar

Article - wd:Q27022289

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