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Age-dependent neuroinflammation and cognitive decline in a novel Ala152Thr-Tau transgenic mouse model of PSP and AD.

автор

Eva-Maria Mandelkow

2000 -

Frank Johannes Dennissen

опубликовано в: Acta Neuropathologica Communications

дата публикации: 2016-02-25

главная тема: воспаление, neuronitis

Cites articles 118

Дата

Заголовок

Авторы

2015-10-13

Neuronal uptake and propagation of a rare phosphorylated high-molecular-weight tau derived from Alzheimer's disease brain

Daniel Irimia, Hansang Cho, Bradley Hyman, Matthew Frosch
2014

Tau overexpression impacts a neuroinflammation gene expression network perturbed in Alzheimer's disease

John P. Corradi
2014-08-07

Microglial phenotypes and toll-like receptor 2 in the substantia nigra and hippocampus of incidental Lewy body disease cases and Parkinson's disease patients

Benjamin Drukarch
2014-07-08

Tracking neuroinflammation in Alzheimer's disease: the role of positron emission tomography imaging

Pedro Rosa-Neto, Serge Gauthier
2014-06-01

Inflammation in neurodegenerative diseases--an update

Johannes M van Noort
2013-01-01

Gene targeting in mice: a review

Klaus Okkenhaug
2013-08-29

Genetic correction of tauopathy phenotypes in neurons derived from human induced pluripotent stem cells

Bruce L. Miller, William Seeley, Adam L Boxer, Kenneth S. Kosik
2013-11-26

Chaperone-mediated autophagy: roles in disease and aging

Ana María Cuervo, Esther Wong
2013-10-19

Neuroinflammation: the role and consequences

Marcela Vizcaychipi, Daqing Ma, Monty Lyman, Xunming Ji
2013-09-27

A novel MAPT mutation, G55R, in a frontotemporal dementia patient leads to altered Tau function

Maria Barcikowska, Cezary Zekanowski, Anna Barczak, Mariusz Berdynski
2013-06-25

Impaired proteasomal degradation enhances autophagy via hypoxia signaling in Drosophila
2013-03-23

Tau degradation: the ubiquitin-proteasome system versus the autophagy-lysosome system
2013-10-01

Neurodegenerative disease phenotypes in carriers of MAPT p.A152T, a risk factor for frontotemporal dementia spectrum disorders and Alzheimer disease

Rosa Rademakers, Bruce L. Miller, William Seeley, Adam L Boxer, Gil D Rabinovici, Daniel Geschwind, Michael Geschwind
2013-08-05

Trehalose rescues Alzheimer's disease phenotypes in APP/PS1 transgenic mice
2013-05-18

Pallidonigroluysian atrophy associated with p.A152T variant in MAPT.

Dennis W. Dickson, Jonathan Graff-Radford, Jennifer L Whitwell
2012

The role of tau in neurodegenerative diseases and its potential as a therapeutic target
2012-05

The clinical problem of symptomatic Alzheimer disease and mild cognitive impairment

David M. Holtzman
2012

Trans-synaptic spread of tau pathology in vivo

Catherine Taylor Clelland
2012-02-01

Propagation of tau pathology in a model of early Alzheimer's disease

Marc Suárez-Calvet, Tara L Spires-Jones, Bradley Hyman, Karen Ashe, Christopher M William, Rose Pitstick, George Carlson, Alix de Calignon, Manuela Polydoro, David H Adamowicz, Naruhiko Sahara
2012-11-29

Making the brain glow: in vivo bioluminescence imaging to study neurodegeneration

Eva-Maria Mandelkow
2012-09-24

Human P301L-mutant tau expression in mouse entorhinal-hippocampal network causes tau aggregation and presynaptic pathology but no cognitive deficits

Eliezer Masliah, Lennart Mucke
2012-07-01

Biochemistry and cell biology of tau protein in neurofibrillary degeneration

Eva-Maria Mandelkow, Eckhard Mandelkow
2012-05-29

Imaging of microglia in patients with neurodegenerative disorders

Marios Politis, Paola Piccini
2012-05-16

The MAPT p.A152T variant is a risk factor associated with tauopathies with atypical clinical and neuropathological features

Andrew John Lees, Харди, Джон, Georgia Xiromerisiou, Janice Holton
2012-05-04

Lipopolysaccharide-induced neuroinflammation leads to the accumulation of ubiquitinated proteins and increases susceptibility to neurodegeneration induced by proteasome inhibition in rat hippocampus

Cristina Pintado, Antonia Gutierrez, Javier Vitorica, Angelica Castaño, Diego Ruano
2012-05-03

Evidence for a role of the rare p.A152T variant in MAPT in increasing the risk for FTD-spectrum and Alzheimer's diseases

Dennis W. Dickson, Alexis Brice, Margaret A. Pericak-Vance, Eva-Maria Mandelkow, Renee L. Sears, Elizabeth Finger, Simon Lovestone, Lindsay A. Farrer, Eckhard Mandelkow, Charles L White, John Q. Trojanowski, Elisavet Preza, Richard Mayeux, Ryan J Uitti, Zbigniew K Wszolek, Eliezer Masliah, Rosa Rademakers, Ronald C. Petersen, Bruce L. Miller, Owen A. Ross, Michelle K Lupton, Jonathan L Haines, Thomas G Beach, Didier Hannequin, Adam L Boxer, Daniel Geschwind, Bradley F Boeve, Bernardino F. Ghetti, Matthew Frosch, Michael Geschwind, Neill R Graff-Radford, Suzee E Lee, Robert A. Stern, Matt Baker, Anna M Karydas, Giovanni Coppola, Carol F Lippa, Eileen H Bigio, Vivianna M Van Deerlin, Isabelle Le Ber, Alexandra I Soto-Ortolaza, D Galasko, Marla Gearing, Jean Paul G Vonsattel, Juan C Troncoso, Yvette Bordelon, Mario F Mendez, Beth A Dombroski, Roger L Albin, Helena Chui, Allan Levey, Andrew P Lieberman, John M Ringman, Alzheimer's Disease Genetics Consortium, Gerard D Schellenberg, Charles DeCarli, Jorge L Juncos, Alden Y Huang
2012-02-05

Synapse loss induced by interleukin-1β requires pre- and post-synaptic mechanisms
2012-02-01

Lifelong rapamycin administration ameliorates age-dependent cognitive deficits by reducing IL-1β and enhancing NMDA signaling

Arlan G. Richardson
2012-01-01

Misfolded α-synuclein and Toll-like receptors: therapeutic targets for Parkinson's disease
2012-04-25

Cognitive defects are reversible in inducible mice expressing pro-aggregant full-length human Tau.

Eva-Maria Mandelkow, Ann Van der Jeugd, Tariq Ahmed
2012-05-17

Proteasome inhibition leads to early loss of synaptic proteins in neuronal culture

Clive Ballard, Paul T. Francis, Natasha Bajic
2011-09-28

Inducing autophagy by rapamycin before, but not after, the formation of plaques and tangles ameliorates cognitive deficits

Arlan G. Richardson

Статья - wd:Q27317039

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