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NS3 is a serine protease required for processing of hepatitis C virus polyprotein

author

Raffaele De Francesco

published in: Journal of Virology

date of publication: 1993-07-01

main subject: Hepatitis C virus, virus, hepatitis C

Cites articles 31

Date

Title

Authors

1992-03

Cleavage of the dengue virus polyprotein at the NS3/NS4A and NS4B/NS5 junctions is mediated by viral protease NS2B-NS3, whereas NS4A/NS4B may be processed by a cellular protease
1992-12

Processing and localization of Dengue virus type 2 polyprotein precursor NS3-NS4A-NS4B-NS5
1992-09-01

Expression and characterization of glycoprotein gp35 of hepatitis C virus using recombinant vaccinia virus

Yoshiharu Matsuura
1991-05

Both nonstructural proteins NS2B and NS3 are required for the proteolytic processing of dengue virus nonstructural proteins
1991-03

Structure and organization of the hepatitis C virus genome isolated from human carriers
1991-06

Expression of processed core protein of hepatitis C virus in mammalian cells
1991-03-15

Genetic organization and diversity of the hepatitis C virus
1991-07-01

Gene mapping of the putative structural region of the hepatitis C virus genome by in vitro processing analysis
1991-09

Pestivirus gene expression: protein p80 of bovine viral diarrhea virus is a proteinase involved in polyprotein processing,Pestivirus gene expression: Protein p80 of bovine viral diarrhea virus is a proteinase involved in polyprotein processing
1991-08

Molecular biology of the hepatitis C viruses: implications for diagnosis, development and control of viral disease

Michael Houghton
1990-08

Pestivirus glycoprotein which induces neutralizing antibodies forms part of a disulfide-linked heterodimer

Till Rümenapf
1990-09

Cleavage of dengue virus NS1-NS2A requires an octapeptide sequence at the C terminus of NS1
1990-12

Molecular cloning of the human hepatitis C virus genome from Japanese patients with non-A, non-B hepatitis
1990-03

Hepatitis C virus shares amino acid sequence similarity with pestiviruses and flaviviruses as well as members of two plant virus supergroups

Robert H. Purcell
1990-11

Evidence that the N-terminal domain of nonstructural protein NS3 from yellow fever virus is a serine protease responsible for site-specific cleavages in the viral polyprotein

Charles M. Rice
1990-07-01

Production of yellow fever virus proteins in infected cells: identification of discrete polyprotein species and analysis of cleavage kinetics using region-specific polyclonal antisera

Charles M. Rice
1990-12-01

The putative nucleocapsid and envelope protein genes of hepatitis C virus determined by comparison of the nucleotide sequences of two isolates derived from an experimentally infected chimpanzee and healthy human carriers

Michael Houghton
1989-05

Proper processing of dengue virus nonstructural glycoprotein NS1 requires the N-terminal hydrophobic signal sequence and the downstream nonstructural protein NS2a

Robert M. Chanock
1989-04-21

Isolation of a cDNA clone derived from a blood-borne non-A, non-B viral hepatitis genome

Michael Houghton
1989-04-21

An assay for circulating antibodies to a major etiologic virus of human non-A, non-B hepatitis

Harvey J. Alter, Robert H. Purcell
1989-02-01

Recent advances in pestivirus research
1989-04-01

Maturation of Japanese encephalitis virus glycoproteins produced by infected mammalian and mosquito cells
1989-01-01

Production and properties of chimeric antibody molecules
1988-08-11

A general method of in vitro preparation and specific mutagenesis of DNA fragments: study of protein and DNA interactions
1988-07-15

Single-step purification of polypeptides expressed in Escherichia coli as fusions with glutathione S-transferase
1988-10-01

Comparisons of the pestivirus bovine viral diarrhoea virus with members of the flaviviridae
1987-12-01

Sequence and translation of the murine coronavirus 5'-end genomic RNA reveals the N-terminal structure of the putative RNA polymerase
1986-11

Eukaryotic transient-expression system based on recombinant vaccinia virus that synthesizes bacteriophage T7 RNA polymerase

Bernard Moss
1985-08-23

Nucleotide sequence of yellow fever virus: implications for flavivirus gene expression and evolution

Charles M. Rice
1984-09-25

Primary structural comparison of RNA-dependent polymerases from plant, animal and bacterial viruses
1984-01-01

Analysis of adenovirus transforming proteins from early regions 1A and 1B with antisera to inducible fusion antigens produced in Escherichia coli

Article - wd:Q27486059

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