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Structural basis for the multiple interactions of the MyD88 TIR domain in TLR4 signaling

forfatter

Masahiro Shirakawa

udgivet i: Proceedings of the National Academy of Sciences

dato for udgivelse: 2009-06-23

sprog: engelsk

main subject: Toll-like receptor

Cites articles 40

Date

Titel

Forfattere

2009-01-01

Structure and regulation of cytoplasmic adapter proteins involved in innate immune signaling

Tom P Monie
2008-08-01

Pyogenic bacterial infections in humans with MyD88 deficiency

Jean-Laurent Casanova, Anne Puel, Capucine Picard, Jacques Banchereau, Hui Xiao, Pegah Ghandil, Manel Juan, Laia Alsina, Damien Chaussabel, Jordi Anton, Carlos Rodrigo, Juan I Arostegui, Laurent Abel, Estibaliz Ruiz-Ortiz, Maya Chrabieh, Yildiz Camcioglu
2008-05-02

The crystal structure of the human toll-like receptor 10 cytoplasmic domain reveals a putative signaling dimer

Susanne Flodin, Pär Nordlund, Martin Hammarström, Pål Stenmark, Tomas Nyman
2008-04-01

TRAM couples endocytosis of Toll-like receptor 4 to the induction of interferon-beta

Shizuo Akira, Ruslan Medzhitov
2008-09-29

Positioning of autoimmune TCR-Ob.2F3 and TCR-Ob.3D1 on the MBP85-99/HLA-DR2 complex

Joel Stern, Jack L. Strominger
2007-02-25

A Mal functional variant is associated with protection against invasive pneumococcal disease, bacteremia, malaria and tuberculosis

Chiea Chuen Khor, Aisling Dunne, Amir R Khan, Peter Aaby, Kathryn Maitland, Dominic P. Kwiatkowski, James Berkley, Luke A. J. O'Neill, John Anthony Gerard Scott, Derrick W Crook, Adrian V. S. Hill, Jackson Sillah, Giorgio Sirugo, Christian Lienhardt, Fredrik O Vannberg
2007-05-01

The family of five: TIR-domain-containing adaptors in Toll-like receptor signalling

Luke A. J. O'Neill, Andrew G Bowie
2007-12-26

The RXRalpha C-terminus T462 is a NMR sensor for coactivator peptide binding

David P Cistola
2007-12-10

Tyrosine phosphorylation of MyD88 adapter-like (Mal) is critical for signal transduction and blocked in endotoxin tolerance

Luke A. J. O'Neill
2007-10-29

Signaling to NF-kappaB by Toll-like receptors
2007-08-29

A dimer of the Toll-like receptor 4 cytoplasmic domain provides a specific scaffold for the recruitment of signalling adaptor proteins

Luke A. J. O'Neill, Tom P Monie
2006-04-18

The myristoylation of TRIF-related adaptor molecule is essential for Toll-like receptor 4 signal transduction

Shizuo Akira, Eicke Latz, Luke A. J. O'Neill, Douglas T Golenbock
2006-03

Binding specificity of Toll-like receptor cytoplasmic domains

Jay R Hesselberth
2006-02-24

Pathogen recognition and innate immunity

Satoshi Uematsu
2006-06-02

Phosphoinositide-mediated adaptor recruitment controls Toll-like receptor signaling

Ruslan Medzhitov
2006-07-10

Details of Toll-like receptor:adapter interaction revealed by germ-line mutagenesis

Karine Crozat, Philippe Georgel, Sophie Rutschmann, Bruce A. Beutler, Ian Wilson, Suzanne Mudd, Sosathya Sovath, Zhengfan Jiang
2005-10-01

Cutting edge: molecular structure of the IL-1R-associated kinase-4 death domain and its implications for TLR signaling
2005-04-22

Interactive sites in the MyD88 Toll/interleukin (IL) 1 receptor domain responsible for coupling to the IL1beta signaling pathway

Jacek J. Hawiger, Jozef Zienkiewicz
2004

Automated NMR structure calculation with CYANA

Peter Güntert
2004-07-09

Mal interacts with tumor necrosis factor receptor-associated factor (TRAF)-6 to mediate NF-kappaB activation by toll-like receptor (TLR)-2 and TLR4.

Ashley Mansell, Paul J Hertzog, Elizabeth K Brint, Luke A. J. O'Neill
2004-04-30

Crystal structure of the Toll/interleukin-1 receptor domain of human IL-1RAPL.

Elizabeth K Brint, Liang Tong, Luke A. J. O'Neill
2003-01-20

Inhibition of interleukin 1 receptor/Toll-like receptor signaling through the alternatively spliced, short form of MyD88 is due to its failure to recruit IRAK-4

Jürg Tschopp
2003-07-29

Structural complementarity of Toll/interleukin-1 receptor domains in Toll-like receptors and the adaptors Mal and MyD88

Mikael Ejdebäck, Aisling Dunne, Luke A. J. O'Neill
2002-11-21

The adaptor molecule TIRAP provides signalling specificity for Toll-like receptors

Ruslan Medzhitov, Richard A. Flavell
2001-09-01

TIRAP: an adapter molecule in the Toll signaling pathway

Gregory M Barton
2000-11-01

Structural basis for signal transduction by the Toll/interleukin-1 receptor domains

James L. Manley, Liang Tong
2000-02-01

Identification of two major sites in the type I interleukin-1 receptor cytoplasmic region responsible for coupling to pro-inflammatory signaling pathways
1999-06-07

MD-2, a molecule that confers lipopolysaccharide responsiveness on Toll-like receptor 4
1998-12-11

Defective LPS Signaling in C3H/HeJ and C57BL/10ScCr Mice: Mutations in Tlr4 Gene,Defective LPS signaling in C3H/HeJ and C57BL/10ScCr mice: mutations in Tlr4 gene

Bruce A. Beutler
1998-09-01

Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination,Crystallography & NMR system: A new software suite for macromolecular structure determination

Thomas Simonson, Michael Nilges, Warren Lyford DeLano
1998-05-15

MyD88, an adapter protein involved in interleukin-1 signaling

Jürg Tschopp
1998-07

Targeted disruption of the MyD88 gene results in loss of IL-1- and IL-18-mediated function

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