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Cilium-independent regulation of Gli protein function by Sufu in Hedgehog signaling is evolutionarily conserved

udgivet i: Genes & Development

dato for udgivelse: 2009-08-15

main subject: Smoothened, frizzled class receptor, Patched 1, Kinesin family member 3A, GLI-Kruppel family member GLI1, SUFU negative regulator of hedgehog signaling, Speckle-type BTB/POZ protein, GLI-Kruppel family member GLI2, GLI-Kruppel family member GLI3

Cites articles 97

Date

Titel

Forfattere

2008-08-01

Intraflagellar transport, cilia, and mammalian Hedgehog signaling: analysis in mouse embryonic fibroblasts

Kathryn V. Anderson
2008-09-15

Hedgehog: functions and mechanisms
2008-12-01

G protein Galphai functions immediately downstream of Smoothened in Hedgehog signalling
2008-10-01

A genome-scale analysis of the cis-regulatory circuitry underlying sonic hedgehog-mediated patterning of the mammalian limb

Steven A Vokes
2008-08-01

Pattern formation in the vertebrate neural tube: a sonic hedgehog morphogen-regulated transcriptional network

Eric Dessaud, James Briscoe
2008-06-18

The decoupling of Smoothened from Galphai proteins has little effect on Gli3 protein processing and Hedgehog-regulated chick neural tube patterning

James K. Chen
2008-05-22

Beta-arrestin-mediated localization of smoothened to the primary cilium

Robert Lefkowitz
2008-04-01

The role of kinases in the Hedgehog signalling pathway
2007-07-30

Functional dissection of Rab GTPases involved in primary cilium formation
2007

Cilia and developmental signaling

Kathryn V. Anderson
2007-05-01

The graded response to Sonic Hedgehog depends on cilia architecture

Tamara Caspary, Kathryn V. Anderson
2007-04-18

Genomic characterization of Gli-activator targets in sonic hedgehog-mediated neural patterning

Steven A Vokes, Eric H. Davidson
2007-07-20

Patched1 regulates hedgehog signaling at the primary cilium
2007-12-03

The primary cilia, a 'Rab-id' transit system for hedgehog signaling
2007-10-24

Hedgehog regulates smoothened activity by inducing a conformational switch

Chao Tong
2007-10-01

Regulation of Ci-SCFSlimb binding, Ci proteolysis, and hedgehog pathway activity by Ci phosphorylation

Margery G Smelkinson
2007-02-03

Multiple ubiquitin-dependent processing pathways regulate hedgehog/gli signaling: implications for cell development and tumorigenesis.
2006-05-01

Sonic hedgehog signaling regulates Gli2 transcriptional activity by suppressing its processing and degradation
2006-02-01

Genetic elimination of Suppressor of fused reveals an essential repressor function in the mammalian Hedgehog signaling pathway

Johan Ericson, Karin Heby-Henricson, Rune Toftgård, Stephan Teglund, Björn Rozell, Jessica Svärd, Madelen Persson-Lek, Matthias Lauth
2006-02

Divergence of hedgehog signal transduction mechanism between Drosophila and mammals

Markku Varjosalo
2006-02-01

GLI3-dependent transcriptional repression of Gli1, Gli2 and kidney patterning genes disrupts renal morphogenesis
2006-01-03

Evidence for the direct involvement of {beta}TrCP in Gli3 protein processing
2006-01

Signaling from Smo to Ci/Gli: conservation and divergence of Hedgehog pathways from Drosophila to vertebrates

Danwei Huangfu, Kathryn V. Anderson
2006-11-01

Orchestrating ontogenesis: variations on a theme by sonic hedgehog

Philip W Ingham, Marysia Placzek
2006-09-11

The hedgehog regulated oncogenes Gli1 and Gli2 block myoblast differentiation by inhibiting MyoD-mediated transcriptional activation
2006-07-01

The primary cilium in cell signaling and cancer
2006-05-01

Gli2 is targeted for ubiquitination and degradation by beta-TrCP ubiquitin ligase

Mohammad Saleem
2006-06-01

Decoding the Hedgehog signal in animal development

Jianhang Jia
2006-01-18

Dual degradation signals control Gli protein stability and tumor formation
2006-11-19

Numb is a suppressor of Hedgehog signalling and targets Gli1 for Itch-dependent ubiquitination.

Elisabetta Ferretti, Enrico De Smaele, Agnese Po, Maurizio Alimandi, Giuseppe Giannini
2006-06-01

A hedgehog-induced BTB protein modulates hedgehog signaling by degrading Ci/Gli transcription factor

Chan-Yen Ou
2006-01-18

Modulation of the Suppressor of fused protein regulates the Hedgehog signaling pathway in Drosophila embryo and imaginal discs.

Artikel - wd:Q28585804

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