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Network biology concepts in complex disease comorbidities

著者

Søren Brunak

Cecilia Engel Thomas

この作品が含まれる作品: Nature Reviews Genetics

出版日: 2016-10

言語: 英語

main subject: 合併症

Cites articles 167

Date

タイトル

著者

2016-05

Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci

Søren Brunak, Andres Metspalu, Tõnu Esko, Harm-Jan Westra, Soumya Raychaudhuri, David Ellinghaus, Franziska Degenhardt, Matthias Hübenthal, Sarah Spain, Eva Ellinghaus, Jeffrey C Barrett, Mauro D'Amato, Lude Franke, Stephan Weidinger, Richard C Trembath, Jörn Bethune, Anders Boeck Jensen, Tune H Pers, Ole A. Andreassen, Anders M. Dale, Dermot McGovern, Rinse K Weersma, Stefan Schreiber, Buhm Han, Tom H Karlsen, Trine Folseraas, Andre Franke, Jonathan N. Barker, Wolf Lieb, Matthew A. Brown, Michael Weichenthal, Ulrich Mrowietz, Brian D Juran, Konstantinos N Lazaridis, Luke Jostins
2016-02-15

Autoimmune diseases - connecting risk alleles with molecular traits of the immune system

Soumya Raychaudhuri
2016-03-27

Emerging Role and Therapeutic Implication of Wnt Signaling Pathways in Autoimmune Diseases
2016-03-01

Type 2 Diabetes Mellitus Trajectories and Associated Risks
2016-05-17

Deep Patient: An Unsupervised Representation to Predict the Future of Patients from the Electronic Health Records

Riccardo Miotto, Brian A Kidd
2016-03-14

Marfan Syndrome and Related Disorders: 25 Years of Gene Discovery

Bart L Loeys, Aline Verstraeten
2016-08-01

An ECLIPSE View of Alpha-1 Antitrypsin Deficiency
2016-02-15

Unravelling the human genome-phenome relationship using phenome-wide association studies

William S Bush, Dana Crawford
2016-05-16

A method to decipher pleiotropy by detecting underlying heterogeneity driven by hidden subgroups applied to autoimmune and neuropsychiatric diseases

Suna Onengut-Gumuscu, Soumya Raychaudhuri, Jane Worthington, Wei-Min Chen, Solbritt Rantapää Dahlqvist, Kamil Slowikowski, Lars Klareskog, ピーター・グレガーセン, Tom Huizinga, Naomi R. Wray, Buhm Han, Eli A Stahl, Dorothée Diogo
2016-04-11

Analysis of 589,306 genomes identifies individuals resilient to severe Mendelian childhood diseases

Menachem Fromer, Thomas J. Hudson, Rong Chen, Jianguo Zhang, Lifeng Tian, Yulan Shen, Jason Bobe, ステファン・フレンド, Leif Groop, Hakon Hakonarson, Eric E Schadt, Pamela Sklar
2016-03-03

Health and population effects of rare gene knockouts in adult humans with related parents

Vagheesh Narasimhan, Dan Mason, Jakub Karczewski, Konrad J. Karczewski, Michael R. Barnes, Srikanth Bellary, Nicholas A Bockett, Zhilong Jia, Shane McCarthy, Rosemary McEachan, Anne H O'Donnell-Luria, Constantinos A Parisinos, Laura Southgate, Mark Thomas, Richard C Trembath, John Wright, David A van Heel, Eamonn R Maher
2016-01-29

Comorbidity Analysis According to Sex and Age in Hypertension Patients in China
2016-03-17

Diabetic retinopathy
2016-02-14

Translational bioinformatics in the era of real-time biomedical, health care and wellness data streams

Marcus A Badgeley, Riccardo Miotto, Benjamin S Glicksberg
2016-04-01

Does Protease-Antiprotease Imbalance Explain Chronic Obstructive Pulmonary Disease?
2015-03

A copy number variation map of the human genome

Stephen W. Scherer, Jeffrey R MacDonald, Daniele Merico
2015

Gene Network Rewiring to Study Melanoma Stage Progression and Elements Essential for Driving Melanoma

Abhinav Kaushik
2015-10-22

A human interactome in three quantitative dimensions organized by stoichiometries and abundances

Jörg Mansfeld, Marco Y. Hein, Anthony A. Hyman, Frank Buchholz, Yusuke Toyoda, Ina Poser, Jürgen Cox, Matthias Mann
2015-08-01

Pervasive robustness in biological systems

Michalis Barkoulas
2015-04-27

Understanding multicellular function and disease with human tissue-specific networks

Rene A Zelaya, Boris M Hartmann, Aaron K Wong, Tilo Grosser, Casey S. Greene, Olga Troyanskaya, Daniel I Chasman, Daniel S. Himmelstein, Kara Dolinski, Arjun Krishnan
2015-09-16

Kinome-wide decoding of network-attacking mutations rewiring cancer signaling

Thomas R Cox, Manuela Helmer-Citterich, Janine T. Erler, Jesper Ferkinghoff-Borg, Bernd Bodenmiller
2015-08-06

Molecular and clinical diseasome of comorbidities in exacerbated COPD patients

Ferran Sanz, David M. Mannino, Laura I. Furlong, Milagros Sánchez-Mayor, Ady Angelica Castro-acosta, Rosa Faner
2015-06-02

Genome-wide copy-number variation study of psychosis in Alzheimer's disease

F. Yesim Demirci, Michael Barmada, M. Ilyas Kamboh, Eleanor Feingold
2015-06-01

Basal exon skipping and genetic pleiotropy: A predictive model of disease pathogenesis

Budd A. Tucker, Edwin M. Stone
2015-04-01

Opportunities for drug repositioning from phenome-wide association studies

Majid Rastegar-Mojarad, Zhan Ye
2015-03-16

Causal drift, robust signaling, and complex disease
2015-10-27

Protective alleles and modifier variants in human health and disease

Andrew R. Harper, Eric Topol
2015-12-22

Exome-based case-control association study using extreme phenotype design reveals novel candidates with protective effect in diabetic retinopathy

Mohammed A Aldahmesh, Fowzan S Alkuraya, Dorota Monies
2015-03-12

The PPARγ2 Pro12Ala variant is protective against progression of nephropathy in people with type 2 diabetes

Michele Pinelli, Dario Bruzzese, Olga Vaccaro
2015-04-01

Personalized medicine: Time for one-person trials.
2015-08-20

The dynamic control of signal transduction networks in cancer cells

Walter Kolch, Boris Kholodenko, Melinda Halasz
2015-11-19

Topological robustness analysis of protein interaction networks reveals key targets for overcoming chemotherapy resistance in glioma

Hátylas Azevedo, Carlos Alberto Moreira-Filho

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