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The ground state of embryonic stem cell self-renewal

published in: Nature

date of publication: 2008-05-22

language: English

main subject: embryonic stem cell, stem cell self-renewal

Cites articles 36

Date

Title

Authors

2007-12-01

The selectivity of protein kinase inhibitors: a further update

Simon J. Arthur, Dario Alessi
2007-06-01

Functional redundancy of GSK-3alpha and GSK-3beta in Wnt/beta-catenin signaling shown by using an allelic series of embryonic stem cell lines

James R. Woodgett, Bradley W. Doble
2007-05-28

Indirubin-3'-monoxime inhibits autophosphorylation of FGFR1 and stimulates ERK1/2 activity via p38 MAPK.
2007-08-01

FGF stimulation of the Erk1/2 signalling cascade triggers transition of pluripotent embryonic stem cells from self-renewal to lineage commitment.

Tilo Kunath, Austin Smith
2007-08-01

A discrete period of FGF-induced Erk1/2 signalling is required for vertebrate neural specification.

Marios P. Stavridis, Kate Gillian Storey
2006-11-14

Self-renewal of embryonic stem cells by a small molecule

Peter G. Schultz, Jeong Tae Do
2006-01-01

Filtering transcriptional noise during development: concepts and mechanisms
2006-03-02

Synergistic action of Wnt and LIF in maintaining pluripotency of mouse ES cells.
2005-09-18

Regulated cell-to-cell variation in a cell-fate decision system

Drew Endy, Eduard Serra, Alejandro Colman-Lerner
2005-12-05

WNT/beta-catenin pathway up-regulates Stat3 and converges on LIF to prevent differentiation of mouse embryonic stem cells.
2005-01-26

LIF/STAT3 controls ES cell self-renewal and pluripotency by a Myc-dependent mechanism

Cameron McLean
2004-12-01

Exploitation of KESTREL to identify NDRG family members as physiological substrates for SGK1 and GSK3

James T. Murray, Rudi Marquez, Dietmar Kuhl
2004-01

Maintenance of pluripotency in human and mouse embryonic stem cells through activation of Wnt signaling by a pharmacological GSK-3-specific inhibitor

Paul Greengard, Ali Hemmati-Brivanlou
2004-09-01

Self-renewal of teratocarcinoma and embryonic stem cells

Ian Chambers, Austin Smith
2004-05-01

A novel mechanism for regulating clonal propagation of mouse ES cells
2003-05-30

Functional expression cloning of Nanog, a pluripotency sustaining factor in embryonic stem cells

Susan Tweedie, Ian Chambers
2003-10-01

BMP induction of Id proteins suppresses differentiation and sustains embryonic stem cell self-renewal in collaboration with STAT3

Ian Chambers
2003-01-01

Defined conditions for neural commitment and differentiation
2003-08-01

Genesis of embryonic stem cells

Austin Smith
2003-09-19

An essential function of the mitogen-activated protein kinase Erk2 in mouse trophoblast development

Bertrand Vernay
2002-09-01

Signalling, cell cycle and pluripotency in embryonic stem cells
2002-01

Expression of DeltaNLef1 in mouse epidermis results in differentiation of hair follicles into squamous epidermal cysts and formation of skin tumours

Fiona Watt
2000-10-01

Specificity and mechanism of action of some commonly used protein kinase inhibitors
1999-08-02

STAT3 activation is sufficient to maintain an undifferentiated state of mouse embryonic stem cells
1999-06-01

Suppression of SHP-2 and ERK signalling promotes self-renewal of mouse embryonic stem cells.
1999-03-01

Formation of a primitive ectoderm like cell population, EPL cells, from ES cells in response to biologically derived factors
1998-10-01

Formation of pluripotent stem cells in the mammalian embryo depends on the POU transcription factor Oct4

Ian Chambers, Hans Schöler
1998-07-01

Self-renewal of pluripotent embryonic stem cells is mediated via activation of STAT3

Ian Chambers
1998-10-01

Crystal structure of an angiogenesis inhibitor bound to the FGF receptor tyrosine kinase domain

Moosa Mohammadi, Stevan R Hubbard, Joseph Schlessinger
1997-05-09

Structures of the tyrosine kinase domain of fibroblast growth factor receptor in complex with inhibitors
1997-04-15

Targeted disruption of the mouse Stat3 gene leads to early embryonic lethality
1997-12-01

Inactivation of the FGF-4 gene in embryonic stem cells alters the growth and/or the survival of their early differentiated progeny

Article - wd:Q29547196

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