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The canonical Notch signaling pathway: unfolding the activation mechanism

published in: Cell

date of publication: 2009-04-01

language: English

Cites articles 194

Date

Title

Authors

2008-08

A conserved face of the Jagged/Serrate DSL domain is involved in Notch trans-activation and cis-inhibition

Pietro Roversi, Sacha Jensen, Steven Johnson, Christina Redfield, Susan M. Lea
2008-07-14

Deficiency of Aph1B/C-gamma-secretase disturbs Nrg1 cleavage and sensorimotor gating that can be reversed with antipsychotic treatment
2008-05-27

Notch-deficient skin induces a lethal systemic B-lymphoproliferative disorder by secreting TSLP, a sentinel for epidermal integrity

Jeffrey H Miner, Perry W Grigsby
2008-05-23

RAM-induced Allostery Facilitates Assembly of a Notch Pathway Active Transcription Complex
2008-09-04

Modulating Notch signaling by pathway-intrinsic and pathway-extrinsic mechanisms

Urban Lendahl
2008-08-01

OSM-11 facilitates LIN-12 Notch signaling during Caenorhabditis elegans vulval development

Mike Boxem, Heather Dionne
2008-07-30

Notch and presenilin regulate cellular expansion and cytokine secretion but cannot instruct Th1/Th2 fate acquisition

Chin-Tong Ong, Raphael Kopan
2008-07-06

EGFR signalling as a negative regulator of Notch1 gene transcription and function in proliferating keratinocytes and cancer

Erwin F. Wagner, Reinhard Dummer
2008-07-01

Kuz and TACE can activate Notch independent of ligand
2008-05-01

The big brain aquaporin is required for endosome maturation and notch receptor trafficking
2008-05-23

Glu(332) in the Nicastrin ectodomain is essential for gamma-secretase complex maturation but not for its activity
2008-04-01

The effects of conformational heterogeneity on the binding of the Notch intracellular domain to effector proteins: a case of biologically tuned disorder

Doug Barrick
2008-03-21

Notch-dependent control of myelopoiesis is regulated by fucosylation
2008-03-17

Roles of Pofut1 and O-fucose in mammalian Notch signaling
2008-01-01

Functions of O-fucosyltransferase in Notch trafficking and signaling: towards the end of a controversy?

Nicolas Vodovar
2008-02-01

Endosomal entry regulates Notch receptor activation in Drosophila melanogaster

Thomas Vaccari
2008-01-01

Rumi is a CAP10 domain glycosyltransferase that modifies Notch and is required for Notch signaling

Hugo J. Bellen
2008-01-28

The O-fucose glycan in the ligand-binding domain of Notch1 regulates embryogenesis and T cell development
2008-01-14

Contributions of chaperone and glycosyltransferase activities of O-fucosyltransferase 1 to Notch signaling

Tetsuya Okajima
2008-02-22

Localization of the delta-like-1-binding site in human Notch-1 and its modulation by calcium affinity

Philip Anton van der Merwe
2008-01-08

Modulation of Notch signaling by antibodies specific for the extracellular negative regulatory region of NOTCH3

Wendy Gordon
2007-10-15

Early pancreatic development requires the vertebrate Suppressor of Hairless (RBPJ) in the PTF1 bHLH complex

Qiaoming Long, Mark Magnuson
2007-04

Structural basis for autoinhibition of Notch
2007-04-20

The notch regulator MAML1 interacts with p53 and functions as a coactivator

Vimla Band
2007-11-28

Mutational and energetic studies of Notch 1 transcription complexes
2007-12-01

Investigating the genetic circuitry of mastermind in Drosophila, a notch signal effector

Spiros Artavanis-Tsakonas
2007-10-29

Regulation of Notch signaling by dynamic changes in the precision of S3 cleavage of Notch-1

Masayasu Okochi, Ryota Hashimoto
2007-10-25

Regulation of Notch signaling by glycosylation
2007-10-02

Active gamma-secretase complexes contain only one of each component

Christian Haass, Bart De Strooper
2007-09-01

Mastermind-like 1 Is a specific coactivator of beta-catenin transcription activation and is essential for colon carcinoma cell survival

Chiara Ronchini
2007-07-01

Divergent functions and distinct localization of the Notch ligands DLL1 and DLL3 in vivo
2007-07-23

FBW7 mutations in leukemic cells mediate NOTCH pathway activation and resistance to gamma-secretase inhibitors

Peter R. Strack, Deanne C Tibbitts, Markus Welcker, Jules P Meijerink, Giulio F Draetta

Article - wd:Q29547725

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