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Cancer immunology. Mutational landscape determines sensitivity to PD-1 blockade in non-small cell lung cancer

автор

Jonathan J Havel

Phillip Wong

Martin L Miller

Roberta Zappasodi

Ton Schumacher

1965 -

Jedd D Wolchok

Chris Sander

опубликовано в: Science

дата публикации: 2015-04-03

язык: английский язык

главная тема: немелкоклеточная карцинома легких, иммунология

Cites articles 64

Дата

Заголовок

Авторы

2015-01-01

Molecular and genetic properties of tumors associated with local immune cytolytic activity

Gad Getz, Nir Hacohen
2014-12-06

PD-1 blockade with nivolumab in relapsed or refractory Hodgkin's lymphoma

Ahmad Halwani, Gordon J. Freeman, Margaret A Shipp
2014-11-01

PD-1 blockade induces responses by inhibiting adaptive immune resistance

Christina L. Harview, Bartosz Chmielowski, Antoni Ribas
2014-11-01

Predictive correlates of response to the anti-PD-L1 antibody MPDL3280A in cancer patients

Daniel S Chen, Roy S. Herbst, F Stephen Hodi
2014-11-27

MPDL3280A (anti-PD-L1) treatment leads to clinical activity in metastatic bladder cancer

Joaquim Bellmunt, Daniel S Chen
2014-11-19

Genetic basis for clinical response to CTLA-4 blockade in melanoma

Alexis Desrichard, Logan A. Walsh, Phillip Wong, Travis Hollmann, Kasthuri Kannan, Jedd D Wolchok, Antoni Ribas
2014-08-28

Beyond DNA repair: DNA-PK function in cancer

Karen E Knudsen
2014-07-09

Comprehensive molecular profiling of lung adenocarcinoma
2014-07-15

Anti-programmed-death-receptor-1 treatment with pembrolizumab in ipilimumab-refractory advanced melanoma: a randomised dose-comparison cohort of a phase 1 trial

Richard F. Kefford, Jeffrey S Weber, Anthony M Joshua, Richard W. Joseph, Bartosz Chmielowski, Adil Daud, Jedd D Wolchok, Antoni Ribas, F Stephen Hodi, Roxana S. Dronca, Tara C Gangadhar
2014-10-01

Association of PD-1, PD-1 ligands, and other features of the tumor immune microenvironment with response to anti-PD-1 therapy
2014-12-22

High-throughput epitope discovery reveals frequent recognition of neo-antigens by CD4+ T cells in human melanoma

Arno Velds, Michael Stratton, Hergen Spits
2014-11-01

Checkpoint blockade cancer immunotherapy targets tumour-specific mutant antigens

Джеймс Эллисон, Ruedi Aebersold, Hans-Georg Rammensee, Мардис, Элейн, Gordon J. Freeman, Arlene Sharpe, Maxim N Artyomov, Cornelis J. M. Melief, Etienne Caron
2014-11-01

Predicting immunogenic tumour mutations by combining mass spectrometry and exome sequencing

Jens Fritsche, Zora Modrusan
2014-09-22

Genomic and bioinformatic profiling of mutational neoepitopes reveals new rules to predict anticancer immunogenicity

Alessandro Sette, Jorge Duitama, Ion I. Mandoiu, John Sidney, Brian M. Baker, Steven A Corcelli
2014-06-02

Systematic identification of personal tumor-specific neoantigens in chronic lymphocytic leukemia

Carrie Sougnez, Kristian Cibulskis, Gad Getz, Стейси Гэбриел, Лэндер, Эрик, Nir Hacohen, Jerome Ritz, Vladimir Brusic, John Sidney, Donna Neuberg
2014-06-25

A vaccine targeting mutant IDH1 induces antitumour immunity.

Felix Sahm, Angelika B. Riemer, Шахин, Угур, Manuel A. Friese, Michael Platten, Lukas Bunse, Stefan Pusch, Stefan Eichmüller, Wolfgang Wick, Andreas von Deimling, Stefan Stevanović, Matthias Osswald, Theresa Schumacher, Iris Oezen, Katharina J Rauschenbach, Martina Ott, Jürgen G Okun, Philipp Beckhove
2014-05-01

Cancer immunotherapy based on mutation-specific CD4+ T cells in a patient with epithelial cancer

Alena Gros, Yong-Chen Lu, Розенберг, Стивен
2013-08-22

Signatures of mutational processes in human cancer

Jessica Zucman-Rossi, Stian Knappskog, Anne-Lise Børresen-Dale, Marcin Imielinski, Keiran Raine, Carlos Caldas, Elli Papaemmanuil, Jon Teague, Anne Vincent-Salomon, Michael Stratton, P. Andrew Futreal, Sunil R Lakhani, Matthew Meyerson, Barbara Hutter, Marcel Kool, Stefan M. Pfister, Paul A Northcott, Serena Nik-Zainal, David T. W. Jones, Peter F. Stadler, Ralf Küppers, David Langenberger, Helen Davies, Xose S. Puente, Rafael Valdés-Mas
2013-07-11

Mutational heterogeneity in cancer and the search for new cancer-associated genes

Лэндер, Эрик, Carrie Sougnez, Gad Getz, Kristian Cibulskis, Wendy Winckler, Daniel Auclair, Lauren Ambrogio, Gordon Saksena, Eran Hodis, Nicolas Stransky, Douglas Voet, Kristin Ardlie, Elizabeth Nickerson, Marcin Imielinski, Aaron McKenna, Melissa Parkin, Adam Kiezun, Petar Stojanov, Yotam Drier, Alfredo Hidalgo-Miranda, Trevor J Pugh, Matthew Meyerson, Jaume Mora, Dmitry A. Gordenin, Kimberly Stegmaier, Craig H Mermel, Стейси Гэбриел, Levi A Garraway, Todd Golub, Andrey Sivachenko, Charles W Roberts, Jens G. Lohr, Chip Stewart, Alex H Ramos
2013-06-02

Nivolumab plus ipilimumab in advanced melanoma

Mario Sznol, Jedd D Wolchok
2013-03-29

Cancer genome landscapes

Фогельштейн, Берт, Kenneth W Kinzler, Victor Velculescu, Luis Alberto Diaz Jr, Nickolas Papadopoulos, Shibin Zhou
2013-02

Germline mutations affecting the proofreading domains of POLE and POLD1 predispose to colorectal adenomas and carcinomas

Gilean McVean, Jean-Baptiste Cazier, Sarah Spain, Дэвид Керр, Peter Broderick, Richard Houlston, Enric Domingo, Claire Palles, Peter Donnelly, Ian Tomlinson, Elinor J. Sawyer, Andrew Oliver Mungo Wilkie, Sara E Dobbins, Amy L Sherborne, Крис Холмс, Luis G Carvajal-Carmona, Kimberley M Howarth, Ella Barclay, Maggie Gorman, Zoe Kemp, Anneke Lucassen
2013-07-15

The exomes of the NCI-60 panel: a genomic resource for cancer biology and systems pharmacology

William Reinhold, Sean Davis, Yves Pommier
2013-05-05

Mining exomic sequencing data to identify mutated antigens recognized by adoptively transferred tumor-reactive T cells

Yong-Chen Lu, Colin Gross, Jamie K Teer, Eric Tycksen, Yardena Samuels, Розенберг, Стивен
2013-09-16

Tumor exome analysis reveals neoantigen-specific T-cell reactivity in an ipilimumab-responsive melanoma

Arno Velds, Ton Schumacher, Bianca Heemskerk
2013-06-08

ATHLATES: accurate typing of human leukocyte antigen through exome sequencing

Michael C. Zody, Robi D Mitra
2013-07-10

dbNSFP v2.0: a database of human non-synonymous SNVs and their functional predictions and annotations

Eric Boerwinkle
2013-02-10

Sensitive detection of somatic point mutations in impure and heterogeneous cancer samples

Carrie Sougnez, Kristian Cibulskis, Gad Getz, Стейси Гэбриел, Лэндер, Эрик, Matthew Meyerson, Andrey Sivachenko
2012-11-15

Molecular epidemiology of EGFR and KRAS mutations in 3,026 lung adenocarcinomas: higher susceptibility of women to smoking-related KRAS-mutant cancers

Marc Ladanyi, Mark G Kris, Sandra P D'Angelo
2012-09-09

Comprehensive genomic characterization of squamous cell lung cancers
2012-06-28

Safety, activity, and immune correlates of anti-PD-1 antibody in cancer

Mario Sznol, Charles G. Drake, F Stephen Hodi, Tracee L. McMiller, Suzanne L. Topalian, Drew M Pardoll, Janis M Taube
2012-03

VarScan 2: somatic mutation and copy number alteration discovery in cancer by exome sequencing

Мардис, Элейн

Статья - wd:Q29615679

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