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Mitochondria and cancer

published in: Nature Reviews Cancer

date of publication: 2012-10

language: English

main subject: mitochondrion

Cites articles 167

Date

Title

Authors

2012-07-06

A mitochondrial pyruvate carrier required for pyruvate uptake in yeast, Drosophila, and humans

Noah Dephoure, Eric B Taylor, Steven P. Gygi
2012-02-15

IDH mutation impairs histone demethylation and results in a block to cell differentiation

Patrick S. Ward, Sevin Turcan, Omar Abdel-Wahab, Maria E Figueroa, Donald M O'Rourke, Shelley L. Berger, Ingo K Mellinghoff
2012-02-15

IDH1 mutation is sufficient to establish the glioma hypermethylator phenotype

Carl Campos
2012-09

Mitochondrial DNA nucleoid structure
2012-01-16

Upsides and downsides of reactive oxygen species for cancer: the roles of reactive oxygen species in tumorigenesis, prevention, and therapy

David Hevia, Bharat Aggarwal, Byoungduck Park, Sridevi Patchva
2012-01

Mitochondrial genome instability and ROS enhance intestinal tumorigenesis in APC(Min/+) mice
2012-08-01

IDH1(R132H) mutation increases murine haematopoietic progenitors and alters epigenetics

Anne Brüstle, Guido Reifenberger, Andrew Wakeham, Tak W Mak, Joshua Munger
2012-06-11

Specific mitochondrial DNA mutation in mice regulates diabetes and lymphoma development
2012-06-15

Autophagy and senescence in cancer-associated fibroblasts metabolically supports tumor growth and metastasis via glycolysis and ketone production

Sharon Sneddon, Carmela Guido, Ruth Birbe, Gloria Bonuccelli, Ubaldo E Martinez-Outschoorn, Aristotelis Tsirigos, Anthony Howell, Michael P. Lisanti, Federica Sotgia, Diana Whitaker-Menezes, Richard Pestell, Claudia Capparelli, Renee M Balliet, Timothy G Pestell, Allison Goldberg
2012-06-07

Inhibition of α-KG-dependent histone and DNA demethylases by fumarate and succinate that are accumulated in mutations of FH and SDH tumor suppressors
2012-05-07

Mitochondrial genome instability resulting from SUV3 haploinsufficiency leads to tumorigenesis and shortened lifespan
2012-02-29

Regulation of oxidative phosphorylation complex activity: effects of tissue-specific metabolic stress within an allometric series and acute changes in workload
2012-02-01

mtDNA lineage analysis of mouse L-cell lines reveals the accumulation of multiple mtDNA mutants and intermolecular recombination
2012-02-15

Transformation by the (R)-enantiomer of 2-hydroxyglutarate linked to EGLN activation

Christopher G Duncan, , Ryan E Looper
2012-02-02

Somatic mitochondrial DNA mutations in cancer escape purifying selection and high pathogenicity mutations lead to the oncocytic phenotype: pathogenicity analysis of reported somatic mtDNA mutations in tumors

David C. Samuels
2012-01-03

Human CHCHD4 mitochondrial proteins regulate cellular oxygen consumption rate and metabolism and provide a critical role in hypoxia signaling and tumor progression

Adrian Harris
2011-05

No evidence for a shift in pyruvate kinase PKM1 to PKM2 expression during tumorigenesis

Hans Lehrach, Markus Ralser, Katharina Bluemlein, Nana-Maria Grüning, René G Feichtinger
2011-08-18

A forty-kilodalton protein of the inner membrane is the mitochondrial calcium uniporter

Anna Raffaello, Diego De Stefani, Rosario Rizzuto, Enrico Teardo
2011-08-18

Integrative genomics identifies MCU as an essential component of the mitochondrial calcium uniporter

Victor Koteliansky
2011-05-27

Pyruvate kinase M2 is a PHD3-stimulated coactivator for hypoxia-inducible factor 1

Akhilesh Pandey, Gregg L. Semenza
2011-05

The oncometabolite 2-hydroxyglutarate inhibits histone lysine demethylases

Akane Kawamura, Rasheduzzaman Chowdhury, Christopher J. Schofield, Eleanor A L Bagg, Oliver King, Nathan R Rose, Michael A McDonough, Peter J. Ratcliffe, Ya-Min Tian, Ian J Clifton, Rob Klose, Timothy D W Claridge, Kar Kheng Yeoh, Lars Hillringhaus, Ivanhoe K. H. Leung, Esther C Y Woon
2011-02-24

miR-210: More than a silent player in hypoxia

Simona Greco, Fabio Martelli
2011-12-22

Bioenergetic origins of complexity and disease
2011-12-02

FOXO3a regulates reactive oxygen metabolism by inhibiting mitochondrial gene expression

Barrie Peck, Almut Schulze
2011-11-20

Reductive carboxylation supports growth in tumour cells with defective mitochondria

Lucas B Sullivan, Ralph J DeBerardinis
2011-11-03

Inhibition of pyruvate kinase M2 by reactive oxygen species contributes to cellular antioxidant responses

Dimitrios Anastasiou, George Poulogiannis, Jason W. Locasale, Craig J. Thomas
2011-10-01

Renal cyst formation in Fh1-deficient mice is independent of the Hif/Phd pathway: roles for fumarate in KEAP1 succination and Nrf2 signaling

Benedikt M. Kessler, Julie Adam, Patrick J Pollard, Nicola Ternette, Roman Fischer, Peter J. Ratcliffe, Peter Carmeliet, Linda O'Flaherty
2011-09-26

Identification of additional IDH mutations associated with oncometabolite R(-)-2-hydroxyglutarate production
2011-09-01

Pyruvate kinase triggers a metabolic feedback loop that controls redox metabolism in respiring cells

Markus Ralser, Mark Rinnerthaler, Hans Lehrach, Michael Breitenbach, Mirjam M C Wamelink, Katharina Bluemlein, Nana-Maria Grüning, Michael Mülleder
2011-11-17

Warburg meets autophagy: cancer-associated fibroblasts accelerate tumor growth and metastasis via oxidative stress, mitophagy, and aerobic glycolysis

Iset Medina Vera, Ricardo M C Gândara, Sharon Sneddon, Ubaldo E Martinez-Outschoorn, Anthony Howell, Richard Pestell, Michael P Lisanti, Stephanos Pavlides
2011-08-17

Haem oxygenase is synthetically lethal with the tumour suppressor fumarate hydratase

Julie Adam, Patrick J Pollard, Eyal Gottlieb, Christian Frezza, Eytan Ruppin, Ian Tomlinson, Ralph J DeBerardinis
2011-07-13

SDH mutations in cancer

Ian Tomlinson

Article - wd:Q29616610

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