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Insulin signalling to mTOR mediated by the Akt/PKB substrate PRAS40

author

Do-Hyung Kim

published in: Nature Cell Biology

date of publication: 2007-02-04

language: English

main subject: preproinsulin

Cites articles 29

Date

Title

Authors

2006-01

Nutrients suppress phosphatidylinositol 3-kinase/Akt signaling via raptor-dependent mTOR-mediated insulin receptor substrate 1 phosphorylation

Konstantin Kandror
2006-08-17

mSin1 is necessary for Akt/PKB phosphorylation, and its isoforms define three distinct mTORC2s

David M. Sabatini
2005-04-26

Rheb binds and regulates the mTOR kinase
2005-02-01

Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex

David M. Sabatini
2005-07-15

Akt activates the mammalian target of rapamycin by regulating cellular ATP level and AMPK activity.

Nahum Sonenberg
2005-06-23

Genetic interaction of Lobe with its modifiers in dorsoventral patterning and growth of the Drosophila eye.
2005-10-01

Expression of proline-rich Akt-substrate PRAS40 in cell survival pathway and carcinogenesis

Gavin Porter
2004-08-11

Absence of S6K1 protects against age- and diet-induced obesity while enhancing insulin sensitivity

M Joaquin, George Thomas
2004-07-27

Rictor, a novel binding partner of mTOR, defines a rapamycin-insensitive and raptor-independent pathway that regulates the cytoskeleton

Hediye Erdjument-Bromage, Paul Tempst, Do-Hyung Kim, David M. Sabatini
2004-11

Mammalian TOR complex 2 controls the actin cytoskeleton and is rapamycin insensitive

Robbie Loewith, Estela Jacinto
2004-02-18

Neuroprotective role of a proline-rich Akt substrate in apoptotic neuronal cell death after stroke: relationships with nerve growth factor
2004-10-01

Tsc2 is not a critical target of Akt during normal Drosophila development
2004-07-01

Regulation of the TSC pathway by LKB1: evidence of a molecular link between tuberous sclerosis complex and Peutz-Jeghers syndrome

Nabeel Bardeesy, Ronald A. DePinho
2004-11-19

Effects of rapamycin in the Eker rat model of tuberous sclerosis complex
2003-06

Rheb is a direct target of the tuberous sclerosis tumour suppressor proteins
2003-12-11

Genetics: influence of TOR kinase on lifespan in C. elegans
2003-04-01

GbetaL, a positive regulator of the rapamycin-sensitive pathway required for the nutrient-sensitive interaction between raptor and mTOR

Hediye Erdjument-Bromage, Paul Tempst, Do-Hyung Kim, David M. Sabatini
2003-01-10

Identification of a proline-rich Akt substrate as a 14-3-3 binding partner

Morris J. Birnbaum
2003-08

Integration of growth factor and nutrient signaling: implications for cancer biology

Stuart Schreiber
2002-09

TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signalling
2002-07-01

Identification of the tuberous sclerosis complex-2 tumor suppressor gene product tuberin as a target of the phosphoinositide 3-kinase/akt pathway

Andrew R. Tee
2002-09

Two TOR complexes, only one of which is rapamycin sensitive, have distinct roles in cell growth control

Robbie Loewith, Stephan Wullschleger, Estela Jacinto, José L. Crespo
2002-07-26

mTOR interacts with raptor to form a nutrient-sensitive complex that signals to the cell growth machinery

Hediye Erdjument-Bromage, Paul Tempst, Do-Hyung Kim, David M. Sabatini
2002-07-26

Raptor, a binding partner of target of rapamycin (TOR), mediates TOR action

Kenta Hara
2002-10-15

Empirical statistical model to estimate the accuracy of peptide identifications made by MS/MS and database search

Ruedi Aebersold, Alexey I. Nesvizhskii, Eugene Kolker, Andrew Keller
2002-09-01

Tsc tumour suppressor proteins antagonize amino-acid-TOR signalling
2001-11-01

Mammalian TOR: a homeostatic ATP sensor
1997-07-04

Phosphorylation of the translational repressor PHAS-I by the mammalian target of rapamycin
1994-11-01

An approach to correlate tandem mass spectral data of peptides with amino acid sequences in a protein database

Jimmy K. Eng

Article - wd:Q29617097

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