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The RAF proteins take centre stage

published in: Nature Reviews Molecular Cell Biology

date of publication: 2004-11

language: English

Cites articles 83

Date

Title

Authors

2004-04-02

Dynamic changes in C-Raf phosphorylation and 14-3-3 protein binding in response to growth factor stimulation: differential roles of 14-3-3 protein binding sites

Joachim Nickel, Michael Sendtner
2004-03-19

Mechanism of activation of the RAF-ERK signaling pathway by oncogenic mutations of B-RAF

Caroline J Springer, Richard Marais
2004-03-26

Constitutive activation of the Ras-Raf signaling pathway in metastatic melanoma is associated with poor prognosis

Eva-Bettina Bröcker, Jürgen C Becker, Roland Houben, Patrick Terheyden
2004-08-01

B-RAF is a therapeutic target in melanoma

Richard Marais, Caroline J Springer
2003-08-19

Protein phosphatase 2A positively regulates Ras signaling by dephosphorylating KSR1 and Raf-1 on critical 14-3-3 binding sites
2003

Regulation of MAP kinase signaling modules by scaffold proteins in mammals
2003-11

Human homologue of Drosophila CNK interacts with Ras effector proteins Raf and Rlf
2003-10-01

CI-1040 (PD184352), a targeted signal transduction inhibitor of MEK (MAPKK).
2003-05-01

Ras proteins: different signals from different locations
2003-06-11

Protein kinase A blocks Raf-1 activity by stimulating 14-3-3 binding and blocking Raf-1 interaction with Ras.

Richard Marais
2003-01-27

Phosphorylation of Raf-1 by p21-activated kinase 1 and Src regulates Raf-1 autoinhibition
2003-03-07

Serine 338 phosphorylation is dispensable for activation of c-Raf1.
2003-10-01

Raf and the road to cell survival: a tale of bad spells, ring bearers and detours
2003-07-01

Role of Raf in vascular protection from distinct apoptotic stimuli
2002-06-27

Mutations of the BRAF gene in human cancer

Georgia Chenevix-Trench, Jon Teague, Sarah Edkins, Richard Wooster, Hayley Woffendin, Kristian Gray, Giuseppe Palmieri, Norman Maitland, Richard Marais, Darren Hargrave, Janet Shipley, P. Andrew Futreal, Andrew Menzies, Darell D. Bigner, Michael Stratton, Helen Davies
2002-05-01

Cyclic AMP-dependent kinase regulates Raf-1 kinase mainly by phosphorylation of serine 259.

Harald Mischak, Walter Kolch, Peter E Shaw
2002-07-01

14-3-3 antagonizes Ras-mediated Raf-1 recruitment to the plasma membrane to maintain signaling fidelity

Richard Marais
2002-06-01

Cyclic AMP blocks cell growth through Raf-1-dependent and Raf-1-independent mechanisms

Richard Marais
2002-01-01

ERK signalling and oncogene transformation are not impaired in cells lacking A-Raf

Richard Marais, Catrin Pritchard
2002-09-01

Fidelity and spatio-temporal control in MAP kinase (ERKs) signalling

Jacques Pouysségur
2001-04-01

MEK kinase activity is not necessary for Raf-1 function
2001-07-05

Protein phosphatases 1 and 2A promote Raf-1 activation by regulating 14-3-3 interactions
2001-11-30

Interaction between active Pak1 and Raf-1 is necessary for phosphorylation and activation of Raf-1

Mengwei Zang, Zhijun Luo
2001-04

S338 phosphorylation of Raf-1 is independent of phosphatidylinositol 3-kinase and Pak3

Richard Marais
2001-07-03

Raf-1 promotes cell survival by antagonizing apoptosis signal-regulating kinase 1 through a MEK-ERK independent mechanism
2001-04-01

Embryonic lethality and fetal liver apoptosis in mice lacking the c-raf-1 gene

Manuela Baccarini, Mario Mikula, Martin Schreiber, Rotraud Wieser, Erwin F. Wagner
2001-11-14

14-3-3 proteins: active cofactors in cellular regulation by serine/threonine phosphorylation
2001-05-01

Phosphorylation site specificity of the Pak-mediated regulation of Raf-1 and cooperativity with Src.
2001-12-01

Erythropoietin-stimulated Raf-1 tyrosine phosphorylation is associated with the tyrosine kinase Lyn in J2E erythroleukemic cells

Richard Marais
2001-03-26

Microtubule integrity regulates Pak leading to Ras-independent activation of Raf-1. insights into mechanisms of Raf-1 activation

Mengwei Zang
2001-07-01

Positive and negative regulation of Raf kinase activity and function by phosphorylation
2001-03-13

Identification of the mechanisms regulating the differential activation of the mapk cascade by epidermal growth factor and nerve growth factor in PC12 cells

Walter Kolch

Article - wd:Q29620153

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