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Hypothalamic programming of systemic ageing involving IKK-β, NF-κB and GnRH

author

Guo Zhang

published in: Nature

date of publication: 2013-05-01

language: English

main subject: NF-κB

Cites articles 44

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Title

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2012-09-02

IKKβ/NF-κB disrupts adult hypothalamic neural stem cells to mediate a neurodegenerative mechanism of dietary obesity and pre-diabetes
2012-03-28

Genes against aging
2011-10-25

Microglial cell origin and phenotypes in health and disease
2011-08-31

The ageing systemic milieu negatively regulates neurogenesis and cognitive function

Jian Luo, Kira I Mosher, Markus Britschgi, Alexander Eggel, Sebastien Couillard-Despres, Jeffrey Kaye, Joseph Quinn, Thomas A. Rando, Tony Wyss-Coray, Ludwig Aigner
2011-07-22

Defective hypothalamic autophagy directs the central pathogenesis of obesity via the IkappaB kinase beta (IKKbeta)/NF-kappaB pathway
2011-05-13

An ADIOL-ERβ-CtBP transrepression pathway negatively regulates microglia-mediated inflammation

Christopher K Glass
2011-03-16

Toll-like receptor signaling in neural plasticity and disease

Eitan Okun, Mark Mattson
2011-01-31

Neural dysregulation of peripheral insulin action and blood pressure by brain endoplasmic reticulum stress
2011-09-01

Transmembrane tumour necrosis factor is neuroprotective and regulates experimental autoimmune encephalomyelitis via neuronal nuclear factor-kappaB.

Hans Lassmann, David E. Szymkowski, Michael Karin
2011-06-05

Uncoupling the mechanisms of obesity and hypertension by targeting hypothalamic IKK-β and NF-κB

Guo Zhang
2010-12-21

Effects of a growth hormone-releasing hormone antagonist on telomerase activity, oxidative stress, longevity, and aging in mice

Andrew Schally, William A Banks, Irving Vidaurre
2010-08-09

Defective feedback regulation of NF-kappaB underlies Sjogren's syndrome in mice with mutated kappaB enhancers of the IkappaBalpha promoter

Jason Fleming, Huamin Wang
2010-03-01

Mechanisms underlying inflammation in neurodegeneration

Beate Winner, Fred Gage, Maria C Marchetto
2009-10-21

Requirement for NF-kappaB signalling in a mouse model of lung adenocarcinoma

Tyler Jacks
2009-10-01

Immune activation in brain aging and neurodegeneration: too much or too little?

Tony Wyss-Coray
2009-07-01

Transcriptional integration of TLR2 and TLR4 signaling at the NCoR derepression checkpoint

Valentina Perissi, Serena Ghisletti, Christopher K Glass
2009-07-16

Rapamycin fed late in life extends lifespan in genetically heterogeneous mice

Richard A Miller
2009-04-03

A Nurr1/CoREST pathway in microglia and astrocytes protects dopaminergic neurons from inflammation-induced death

Fred Gage, Leah F Boyer
2009-01-01

SIRT6 links histone H3 lysine 9 deacetylation to NF-kappaB-dependent gene expression and organismal life span

Adam S Adler
2009-09-02

Epigenetic gambling and epigenetic drift as an antagonistic pleiotropic mechanism of aging.
2008-10-01

Hypothalamic IKKbeta/NF-kappaB and ER stress link overnutrition to energy imbalance and obesity

Michael Karin, Hua Bai, Guo Zhang, Xiaoqing Zhang
2008-03-18

Age-related changes in bone morphology are accelerated in group VIA phospholipase A2 (iPLA2beta)-null mice

Kevin Yarasheski, Deborah V Novack, Blaine A Christiansen
2008-03-27

SIRT6 is a histone H3 lysine 9 deacetylase that modulates telomeric chromatin

Or Gozani
2008-08-01

Microglia--a wrench in the running wheel?

Tony Wyss-Coray
2007-12-15

Motif module map reveals enforcement of aging by continual NF-kappaB activity

Jennifer Y. Zhang, Eran Segal, Adam S Adler
2007-07-01

Brain IRS2 signaling coordinates life span and nutrient homeostasis
2007-05-31

Two neurons mediate diet-restriction-induced longevity in C. elegans
2007-02-01

Synapse loss and microglial activation precede tangles in a P301S tauopathy mouse model

Yasumasa Yoshiyama, John Q. Trojanowski, Tetsuya Suhara
2006-10-01

NF-kappaB/Rel regulates inhibitory and excitatory neuronal function and synaptic plasticity
2006-04-01

NF-kappaB regulates spatial memory formation and synaptic plasticity through protein kinase A/CREB signaling

Sylvie Mémet
2005-09

Overview of caloric restriction and ageing
2005-02-01

Targeted expression of the human uncoupling protein 2 (hUCP2) to adult neurons extends life span in the fly.

Stephen L. Helfand

Article - wd:Q30543829

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