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Differential connexin function enhances self-renewal in glioblastoma

author

Justin D Lathia

Jeremy N Rich

published in: Cell Reports

date of publication: 2015-05-07

main subject: glioblastoma

Cites articles 56

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Aviv Regev, Itay Tirosh, Shawn M. Gillespie, Alex K. Shalek, Daniel P Cahill, Brian V. Nahed, Samuel D Rabkin, Orit Rozenblatt-Rosen, Robert L Martuza, Bradley Bernstein
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Temozolomide resistance in glioblastoma cells occurs partly through epidermal growth factor receptor-mediated induction of connexin 43.
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Connexin hemichannels in the lens

Eric C. Beyer
2013-12-27

High-throughput flow cytometry screening reveals a role for junctional adhesion molecule a as a cancer stem cell maintenance factor

Anita B Hjelmeland, Roger E McLendon, Justin D Lathia, Jeremy N Rich
2013-05-18

Connexin43 confers Temozolomide resistance in human glioma cells by modulating the mitochondrial apoptosis pathway
2013-03-26

Carbenoxolone enhances TRAIL-induced apoptosis through the upregulation of death receptor 5 and inhibition of gap junction intercellular communication in human glioma

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2012-12-01

X-linked Charcot-Marie-Tooth disease.

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The role of Connexin 46 promoter in lens and other hypoxic tissues

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2012-06-01

Cancer stem cells: current status and evolving complexities

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2012-01-26

miR-221/222 is the regulator of Cx43 expression in human glioblastoma cells
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Connexin 43 reverses malignant phenotypes of glioma stem cells by modulating E-cadherin

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Glioma stem cell proliferation and tumor growth are promoted by nitric oxide synthase-2

Steven A. Goldman, Anita B Hjelmeland, Roger E McLendon, Justin D Lathia, Jeremy N Rich
2011-05-23

Investigation of the reciprocal relationship between the expression of two gap junction connexin proteins, connexin46 and connexin43.
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An open-label, single-dose, crossover study of the pharmacokinetics and metabolism of two oral formulations of 1-octanol in patients with essential tremor

Mark Hallett
2011-04-01

Nonreceptor tyrosine kinase BMX maintains self-renewal and tumorigenic potential of glioblastoma stem cells by activating STAT3.

Anita B Hjelmeland, Roger E McLendon, Justin D Lathia, Jeremy N Rich
2011-07-22

Gap junctions in human glioblastomas: implications for suicide gene therapy
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Epidermal growth factor receptor expression identifies functionally and molecularly distinct tumor-initiating cells in human glioblastoma multiforme and is required for gliomagenesis

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2010-05-01

Integrin alpha 6 regulates glioblastoma stem cells

Anita B Hjelmeland, Roger E McLendon, Justin D Lathia, Jeremy N Rich
2010-07-01

Gap junctions and connexins as therapeutic targets in cancer
2010-02-10

Communication via gap junctions underlies early functional and beneficial interactions between grafted neural stem cells and the host

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Hypoxia-inducible factors regulate tumorigenic capacity of glioma stem cells

Anita B Hjelmeland, Roger E McLendon, Justin D Lathia, Jeremy N Rich
2009-07-01

Connexins are active participants of hematopoietic stem cell regulation

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2009-03-12

Connexins: a myriad of functions extending beyond assembly of gap junction channels

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Hypoxia promotes expansion of the CD133-positive glioma stem cells through activation of HIF-1alpha

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Article - wd:Q30657733

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