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Clinical grade Treg: GMP isolation, improvement of purity by CD127 Depletion, Treg expansion, and Treg cryopreservation

författare

Luuk B Hilbrands

Frank W M B Preijers

publicerad i: PLOS ONE

utgivningsår: 2008-09-08

språk: engelska

huvudämne: cryopreservation

Refererar artiklar 28

Datum

Titel

Författare

2008-05-21

Ex vivo generation of human alloantigen-specific regulatory T cells from CD4(pos)CD25(high) T cells for immunotherapy

Luuk B Hilbrands
2007-08-01

Regulatory T-cell immunotherapy for tolerance to self antigens and alloantigens in humans

Maria Grazia Roncarolo, Manuela Battaglia
2006-07-10

CD127 expression inversely correlates with FoxP3 and suppressive function of human CD4+ T reg cells
2006-07-03

Expression of interleukin (IL)-2 and IL-7 receptors discriminates between human regulatory and activated T cells

Sarah C Sasson, Barbara Fazekas De St Groth, Michael J. Solomon
2006-02-10

Effective expansion of alloantigen-specific Foxp3+ CD25+ CD4+ regulatory T cells by dendritic cells during the mixed leukocyte reaction

Kayo Inaba, Jeffrey Ravetch, Ralph Steinman
2006-07-21

Efficient and reproducible large-scale isolation of human CD4+ CD25+ regulatory T cells with potent suppressor activity.
2006-03-01

Isolation of CD4+CD25+ regulatory T cells for clinical trials

Matthias Edinger, Mario Assenmacher
2006-05-01

Highly efficient expansion of human CD4+CD25+ regulatory T cells for cellular immunotherapy in patients with graft-versus-host disease
2006-06-28

Ex vivo expansion of human CD4+ CD25high regulatory T cells from transplant recipients permits functional analysis of small blood samples

Luuk B Hilbrands
2006-09-26

In vitro-expanded donor alloantigen-specific CD4+CD25+ regulatory T cells promote experimental transplantation tolerance

Déla Golshayan, Marina Garín
2005-10-01

Post-transplant lymphoproliferative disorders (PTLD) after solid organ transplantation
2005-09-01

Expansion of functional endogenous antigen-specific CD4+CD25+ regulatory T cells from nonobese diabetic mice.
2005-04-01

In vitro expanded human CD4+CD25+ regulatory T cells suppress effector T cell proliferation.
2005-06-01

CD27/CFSE-based ex vivo selection of highly suppressive alloantigen-specific human regulatory T cells.
2005-03-01

The generation of CD25+ CD4+ regulatory T cells that prevent allograft rejection does not compromise immunity to a viral pathogen

Emma Jones
2004-06-01

CD25+ CD4+ T cells, expanded with dendritic cells presenting a single autoantigenic peptide, suppress autoimmune diabetes

Kristin V Tarbell, Ralph Steinman
2004-06-01

In vitro-expanded antigen-specific regulatory T cells suppress autoimmune diabetes
2004-04-15

Large-scale in vitro expansion of polyclonal human CD4(+)CD25high regulatory T cells

Matthias Edinger, Leoni Kunz-Schughart
2004-02-19

Induction of antigen-specific tolerance to bone marrow allografts with CD4+CD25+ T lymphocytes

Olivier Joffre, Denis Hudrisier
2003-12-01

Recipient-type specific CD4+CD25+ regulatory T cells favor immune reconstitution and control graft-versus-host disease while maintaining graft-versus-leukemia

David Klatzmann, Benoit L Salomon, Frédéric Charlotte
2003-04-01

Post-hematopoietic cell transplantation control of graft-versus-host disease by donor CD425 T cells to allow an effective graft-versus-leukemia response
2003-04-01

Cutting edge: cure of colitis by CD4+CD25+ regulatory T cells

Fiona Powrie
2003-08-17

CD4+CD25+ regulatory T cells preserve graft-versus-tumor activity while inhibiting graft-versus-host disease after bone marrow transplantation

Robert S. Negrin
2003-12-01

IL-15 and cognate antigen successfully expand de novo-induced human antigen-specific regulatory CD4+ T cells that require antigen-specific activation for suppression.
2002-08-01

Donor-type CD4(+)CD25(+) regulatory T cells suppress lethal acute graft-versus-host disease after allogeneic bone marrow transplantation
2002-11-01

Cutting edge: CD4+CD25+ regulatory T cells suppress antigen-specific autoreactive immune responses and central nervous system inflammation during active experimental autoimmune encephalomyelitis
1999-02-01

B cell lymphoproliferative disorders following hematopoietic stem cell transplantation: risk factors, treatment and outcome
1999-10-01

Risk of lymphoproliferative disorders after bone marrow transplantation: a multi-institutional study

Hans Joachim Deeg, Elaine Jaffe, Robert N. Hoover

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