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Oxaliplatin, irinotecan and capecitabine as first-line therapy in metastatic colorectal cancer (mCRC): a dose-finding study and pharmacogenomic analysis

pengarang

Mariano Ponz-Sarvise

Ana Chopitea

diterbitkan dalam: British Journal of Cancer

tanggal publikasi: 2010-03-09

subyek utama: Kanker usus besar, Farmakogenomik, oxaliplatin, metastatic colon cancer, irinotecan, Kapesitabin, colorectal carcinoma

Cites articles 46

Date

Judul

Pengarang

2009-05-12

A multicenter phase II study of the combination of oxaliplatin, irinotecan and capecitabine in the first-line treatment of metastatic colorectal cancer
2009-10-26

Association of molecular markers with toxicity outcomes in a randomized trial of chemotherapy for advanced colorectal cancer: the FOCUS trial

Julian Weldon Adlard, Susan D Richman, Philip Quirke
2008-09-16

Pharmacogenetic prediction of clinical outcome in advanced colorectal cancer patients receiving oxaliplatin/5-fluorouracil as first-line chemotherapy
2008-09-16

GSTP1 Ile105Val polymorphism correlates with progression-free survival in MCRC patients treated with or without irinotecan: a study of the Dutch Colorectal Cancer Group

Henk-Jan Guchelaar
2008-05-01

UGT1A1*28 polymorphism predicts irinotecan-induced severe toxicities without affecting treatment outcome and survival in patients with metastatic colorectal carcinoma

Chun-Yu Liu
2008-12-10

Glutathione-S-transferase pi (GSTP1) codon 105 polymorphism is not associated with oxaliplatin efficacy or toxicity in advanced colorectal cancer patients

Henk-Jan Guchelaar, Hans Gelderblom, Cornelis Punt, Dina M Kweekel, Ninja F Antonini, Tahar R. J. H. M. van der Straaten
2008-04-28

Pharmacogenetic approach for capecitabine or 5-fluorouracil selection to be combined with oxaliplatin as first-line chemotherapy in advanced colorectal cancer.

Eduardo Díaz-Rubio
2008-02-01

Thymidylate synthase and methylenetetrahydrofolate reductase gene polymorphisms and toxicity to capecitabine in advanced colorectal cancer patients

Laurent Rivory, Manuela Zucknick
2008-06-03

8-year follow-up of randomized trial: cytoreduction and hyperthermic intraperitoneal chemotherapy versus systemic chemotherapy in patients with peritoneal carcinomatosis of colorectal cancer
2007-12-01

Determination of ERCC2 Lys751Gln and GSTP1 Ile105Val gene polymorphisms in colorectal cancer patients: relationships with treatment outcome

Jacques Robert, Simone Mathoulin-Pélissier
2007-05-01

Identification of a novel single nucleotide polymorphism in the first tandem repeat sequence of the thymidylate synthase 2R allele

Lisa F. Lincz, Fiona E Scorgie, Madhu B Garg
2007-04-01

Pharmacogenetic profiling in patients with advanced colorectal cancer treated with first-line FOLFOX-4 chemotherapy

Annamaria Ruzzo, Fotios Loupakis, Eliana Rulli, Daniele Santini, Paolo Maltese, Alfredo Falcone, Giuseppe Tonini, Gaia Schiavon, Vincenzo Catalano, Emanuele Canestrari, Mauro Magnani, Rita Ficarelli, Renato Bisonni, Irene Floriani, Rosarita Silva, Lucio Giustini
2007-06-01

GSTP1 and MTHFR polymorphisms are related with toxicity in breast cancer adjuvant anthracycline-based treatment

Juan De la Haba-Rodríguez
2007-09-06

Capecitabine plus oxaliplatin and irinotecan regimen every other week: a phase I/II study in first-line treatment of metastatic colorectal cancer

Luigi Celio, Maria Di Bartolomeo, Katia F. Dotti, Sara Pusceddu
2005-10-01

OncoSurge: a strategy for improving resectability with curative intent in metastatic colorectal cancer

John Primrose, Steven R Alberts, Yehuda Patt, Steven A Curley
2005-07-01

Systemic therapy for metastatic colorectal cancer: current options, current evidence
2004-10-01

Rescue surgery for unresectable colorectal liver metastases downstaged by chemotherapy: a model to predict long-term survival

René Adam, Denis Castaing
2004-07-01

A multivariate analysis of genomic polymorphisms: prediction of clinical outcome to 5-FU/oxaliplatin combination chemotherapy in refractory colorectal cancer
2004-06-01

XELOX (capecitabine plus oxaliplatin): active first-line therapy for patients with metastatic colorectal cancer

Eric Van Cutsem, Chris Twelves, Patrick Schöffski, Josep Tabernero Caturla
2004-12-01

Tumor progression while on chemotherapy: a contraindication to liver resection for multiple colorectal metastases?

René Adam, Denis Castaing
2004-12-01

First-line treatment of metastatic colorectal cancer with irinotecan, oxaliplatin and 5-fluorouracil/leucovorin (FOLFOXIRI): results of a phase II study with a simplified biweekly schedule
2003-09-01

Capecitabine and irinotecan as first-line chemotherapy in patients with metastatic colorectal cancer: results of an extended phase I study
2003-09-01

Identification and functional analysis of single nucleotide polymorphism in the tandem repeat sequence of thymidylate synthase gene
2003-09-01

Polymorphism in the thymidylate synthase promoter enhancer region is not an efficacious marker for tumor sensitivity to 5-fluorouracil-based oral adjuvant chemotherapy in colorectal cancer
2003-06-01

A novel single nucleotide polymorphism within the 5' tandem repeat polymorphism of the thymidylate synthase gene abolishes USF-1 binding and alters transcriptional activity

Heinz-Josef Lenz
2003-10-01

Randomized trial of cytoreduction and hyperthermic intraperitoneal chemotherapy versus systemic chemotherapy and palliative surgery in patients with peritoneal carcinomatosis of colorectal cancer,Randomized Trial of Cytoreduction and Hyperthermic Intraperitoneal Chemotherapy Versus Systemic Chemotherapy and Palliative Surgery in Patients With Peritoneal Carcinomatosis of Colorectal Cancer

Vic J Verwaal, Harm van Tinteren
2002-01-01

Combined irinotecan, oxaliplatin and 5-fluorouracil in patients with advanced colorectal cancer. a feasibility pilot study

Javier Cortes, Jokin de Irala
2002-08-01

Irinotecan, oxaliplatin, and 5-fluorouracil/leucovorin combination chemotherapy in advanced colorectal carcinoma: a phase II study

Javier Cortes
2002-12-01

Oxaliplatin plus irinotecan and leucovorin-modulated 5-fluorouracil triplet regimen every other week: a dose-finding study in patients with advanced gastrointestinal malignancies

Antonio Avallone, Francesco Izzo
2002-10-01

Biweekly chemotherapy with oxaliplatin, irinotecan, infusional Fluorouracil, and leucovorin: a pilot study in patients with metastatic colorectal cancer

Antonello Di Paolo, Romano Danesi, Alfredo Falcone, Mario Del Tacca, Giacomo Allegrini, Samanta Cupini
2002-09-01

Significance of nuclear glutathione S-transferase pi in resistance to anti-cancer drugs
2002-02-01

Clinical determinants of survival in patients with 5-fluorouracil-based treatment for metastatic colorectal cancer: results of a multivariate analysis of 3825 patients

David Cunningham, Bengt Glimelius

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