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Versatile role of heparanase in inflammation

published in: Matrix Biology

date of publication: 2013-03-13

main subject: inflammation

Cites articles 128

Date

Title

Authors

2013-01

Increased expression of heparanase in symptomatic carotid atherosclerosis

Lasse Folkersen, Ulf Hedin
2012-10-09

Heparanase enhances the insulin receptor signaling pathway to activate extracellular signal-regulated kinase in multiple myeloma
2012-08-03

Barrett's to oesophageal cancer sequence: a model of inflammatory-driven upper gastrointestinal cancer

John V Reynolds, Stephen G. Maher, Jacintha O'Sullivan
2012-07-13

Inflammation-associated cancer development in digestive organs: mechanisms and roles for genetic and epigenetic modulation

Tsutomu Chiba
2012-05-01

The endoglycosidase heparanase enters the nucleus of T lymphocytes and modulates H3 methylation at actively transcribed genes via the interplay with key chromatin modifying enzymes

Katharine J Goodall, Ivan Poon, Mark D Hulett
2012-06-13

Heparanase overexpression impairs inflammatory response and macrophage-mediated clearance of amyloid-β in murine brain

Ulf Lindahl, Lars Lannfelt
2012-05-10

Dissociation between mature phenotype and impaired transmigration in dendritic cells from heparanase-deficient mice
2012-02-20

Small RNAs targeting transcription start site induce heparanase silencing through interference with transcription initiation in human cancer cells
2012-01-20

Downregulation of heparanase by RNA interference inhibits invasion and tumorigenesis of hepatocellular cancer cells in vitro and in vivo
2012-11-15

Macrophage activation by heparanase is mediated by TLR-2 and TLR-4 and associates with plaque progression

Gabriel Nussbaum
2012-07-22

The pulmonary endothelial glycocalyx regulates neutrophil adhesion and lung injury during experimental sepsis

Eric P Schmidt, Ivor S Douglas, Katherine H Overdier
2012-07-12

Inactivation of heparan sulfate 2-O-sulfotransferase accentuates neutrophil infiltration during acute inflammation in mice

Ding Xu, Jeffrey Esko
2011-12-21

TLR4 dependent heparan sulphate-induced pancreatic inflammatory response is IRF3-mediated

Anders Malmström
2011-05-14

Heparanase affects secretory granule homeostasis of murine mast cells through degrading heparin

Gunnar Pejler
2011-04-01

Heparanase powers a chronic inflammatory circuit that promotes colitis-associated tumorigenesis in mice
2011-03-20

Reactive oxygen species mediate high glucose-induced heparanase-1 production and heparan sulphate proteoglycan degradation in human and rat endothelial cells: a potential role in the pathogenesis of atherosclerosis
2011-02-01

PG545, a dual heparanase and angiogenesis inhibitor, induces potent anti-tumour and anti-metastatic efficacy in preclinical models

Maree Smith
2011-01-21

SST0001, a chemically modified heparin, inhibits myeloma growth and angiogenesis via disruption of the heparanase/syndecan-1 axis
2011-05-01

Proteoglycans in cancer biology, tumour microenvironment and angiogenesis
2011-12-31

Heparanase overexpression reduces carrageenan-induced mechanical and cold hypersensitivity in mice

Zsuzsanna Wiesenfeld-Hallin
2011-03

Hallmarks of Cancer: The Next Generation

Douglas Hanahan, Robert Weinberg
2011-11-23

Fatty acid-induced nuclear translocation of heparanase uncouples glucose metabolism in endothelial cells
2010-12-03

Heparanase plays a dual role in driving hepatocyte growth factor (HGF) signaling by enhancing HGF expression and activity
2010-08-31

Proteoglycans in health and disease: novel roles for proteoglycans in malignancy and their pharmacological targeting

Nikos K. Karamanos, George Tzanakakis
2010-07-01

Preferential up-regulation of heparanase and cyclooxygenase-2 in carcinogenesis of Barrett's oesophagus and intestinal-type gastric carcinoma

Hitoshi Nagatsuka, Hidetsugu Tsujigiwa
2010-06-08

A chemotactic gradient sequestered on endothelial heparan sulfate induces directional intraluminal crawling of neutrophils

Gustaf Christoffersson, Charlotte Rolny, Mia Phillipson
2010-04-02

Macrophage diversity enhances tumor progression and metastasis
2010-01-22

Heparanase-enhanced shedding of syndecan-1 by myeloma cells promotes endothelial invasion and angiogenesis
2009-12-25

Inflammation and oncogenesis: a vicious connection

Michael Karin
2009-12-11

Enoxaparin improves the course of dextran sodium sulfate-induced colitis in syndecan-1-deficient mice

Martin Götte, Wolfram Domschke
2009-09-11

Heparanase expression by Barrett's epithelium and during esophageal carcinoma progression.
2009-11-01

Heparin, heparan sulfate and heparanase in inflammatory reactions

Article - wd:Q33770777

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