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Oligomerization of anthrax toxin protective antigen and binding of lethal factor during endocytic uptake into mammalian cells

author

Stephen H. Leppla

1941 -

Kurt R. Klimpel

1961 -

published in: Infection and Immunity

date of publication: 1999-04-01

language: English

Cites articles 30

Date

Title

Authors

1998-11-01

Characterization of membrane translocation by anthrax protective antigen

R. John Collier
1998-07-01

Anthrax lethal factor cleaves the N-terminus of MAPKKs and induces tyrosine/threonine phosphorylation of MAPKs in cultured macrophages

Chiara Recchi
1998-05-01

Proteolytic inactivation of MAP-kinase-kinase by anthrax lethal factor

Stephen H. Leppla, Nicholas S. Duesbery, Kurt R. Klimpel
1998-03-01

Identification of residues lining the anthrax protective antigen channel

R. John Collier
1997-02-27

Crystal structure of the anthrax toxin protective antigen

Stephen H. Leppla, R. John Collier, Kurt R. Klimpel
1995-06-01

Antigen presentation mediated by recycling of surface HLA-DR molecules

Oddmund Bakke, Valérie Pinet
1994-08-01

Anthrax protective antigen forms oligomers during intoxication of mammalian cells
1994-11-01

Fusions of anthrax toxin lethal factor with shiga toxin and diphtheria toxin enzymatic domains are toxic to mammalian cells

Stephen H. Leppla
1994-09

Anthrax toxin lethal factor contains a zinc metalloprotease consensus sequence which is required for lethal toxin activity

Stephen H. Leppla, Kurt R. Klimpel
1994-01-01

Intracellular trafficking and activation of the furin proprotein convertase: localization to the TGN and recycling from the cell surface
1994-10-01

The cytoplasmic domain of the diphtheria toxin receptor (HB-EGF precursor) is not required for receptor-mediated endocytosis
1994-11-01

The chymotrypsin-sensitive site, FFD315, in anthrax toxin protective antigen is required for translocation of lethal factor

Stephen H. Leppla, Kurt R. Klimpel
1993-11-01

On the role of macrophages in anthrax

R. John Collier
1993-11-01

pH-dependent permeabilization of the plasma membrane of mammalian cells by anthrax protective antigen

R. John Collier
1992-08

Human furin is a calcium-dependent serine endoprotease that recognizes the sequence Arg-X-X-Arg and efficiently cleaves anthrax toxin protective antigen

Stephen H. Leppla, Kurt R. Klimpel
1992-06-01

Expression cloning of a diphtheria toxin receptor: identity with a heparin-binding EGF-like growth factor precursor.

David W. Russell
1992-08-01

Functional characterization of protease-treated Bacillus anthracis protective antigen

Stephen H. Leppla
1992-11-01

Anthrax toxin protective antigen is activated by a cell surface protease with the sequence specificity and catalytic properties of furin

Stephen H. Leppla, Kurt R. Klimpel
1992-06-01

The alpha 2-macroglobulin receptor/low density lipoprotein receptor-related protein binds and internalizes Pseudomonas exotoxin A
1991-10-01

Functional mapping of anthrax toxin lethal factor by in-frame insertion mutagenesis

Stephen H. Leppla, Conrad P. Quinn, Kurt R. Klimpel
1991-10-01

Contribution of individual toxin components to virulence of Bacillus anthracis

Patrick Berche
1991-10-01

Anthrax protective antigen interacts with a specific receptor on the surface of CHO-K1 cells

R. John Collier
1991-08-01

The carboxyl-terminal end of protective antigen is required for receptor binding and anthrax toxin activity.

Stephen H. Leppla, Conrad P. Quinn, Kurt R. Klimpel
1990-11-01

Voltage-dependent block of anthrax toxin channels in planar phospholipid bilayer membranes by symmetric tetraalkylammonium ions. Effects on macroscopic conductance
1989-04-01

Anthrax toxin: channel-forming activity of protective antigen in planar phospholipid bilayers

R. John Collier
1989-11-01

A deleted variant of Bacillus anthracis protective antigen is non-toxic and blocks anthrax toxin action in vivo

Stephen H. Leppla
1988-05-01

Inhibitors of receptor-mediated endocytosis block the entry of Bacillus anthracis adenylate cyclase toxin but not that of Bordetella pertussis adenylate cyclase toxin

Stephen H. Leppla
1986-06-01

Macrophages are sensitive to anthrax lethal toxin through an acid-dependent process
1982-05

Anthrax toxin edema factor: a bacterial adenylate cyclase that increases cyclic AMP concentrations of eukaryotic cells

Stephen H. Leppla
1962-11-01

Purification of the third factor of anthrax toxin

Article - wd:Q34000910

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