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Permanent alteration of PCSK9 with in vivo CRISPR-Cas9 genome editing

author

Chad A. Cowan

published in: Circulation Research

date of publication: 2014-06-10

main subject: CRISPR, Cas9

Cites articles 10

Date

Title

Authors

2014-03-30

Genome editing with Cas9 in adult mice corrects a disease mutation and phenotype

Wen Xue, Markus Grompe, Victor Koteliansky, Tyler Jacks
2013-03-01

Potential of proprotein convertase subtilisin/kexin type 9 based therapeutics
2013-01-03

RNA-guided human genome engineering via Cas9

Kevin M. Esvelt, Marc Güell, Julie E Norville, George M. Church
2013-02-15

Multiplex genome engineering using CRISPR/Cas systems

Xuebing Wu, Patrick D Hsu
2006-07-18

Molecular characterization of loss-of-function mutations in PCSK9 and identification of a compound heterozygote
2006-03-23

Sequence variations in PCSK9, low LDL, and protection against coronary heart disease
2006-09-20

The C679X mutation in PCSK9 is present and lowers blood cholesterol in a Southern African population
2005-04-12

Decreased plasma cholesterol and hypersensitivity to statins in mice lacking Pcsk9

Jay D Horton
2005-01-16

Low LDL cholesterol in individuals of African descent resulting from frequent nonsense mutations in PCSK9.

Alexander Pertsemlidis
2003-06

Mutations in PCSK9 cause autosomal dominant hypercholesterolemia

Jean Weissenbach, Corinne Cruaud, Jean-Pierre Rabès, Michel Krempf, Nabil Seidah, Mathilde Varret, Catherine Boileau, Ludovic Villéger, Marianne Abifadel, Delphine Allard, Claudine Junien, Khadija Ouguerram, Martine Devillers, Suzanne Benjannet, Louise Wickham, Danièle Erlich, Michel Farnier, Eric Bruckert

Article - wd:Q34052814

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