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Immunotherapy of human cancers using gene modified T lymphocytes

author

Malcolm K Brenner

published in: Current Gene Therapy

date of publication: 2009-10-01

language: English

main subject: immunotherapy

Cites articles 140

Date

Title

Authors

2009-09-16

Generation of Epstein-Barr virus-specific cytotoxic T lymphocytes resistant to the immunosuppressive drug tacrolimus (FK506)

Biagio De Angelis, Concetta Quintarelli, Fabrizio Pane, Cliona M Rooney, Malcolm K Brenner, Helen Heslop, Barbara Savoldo, Gianpietro Dotti, Leslie E Huye
2009-09-08

Immunotherapy of metastatic melanoma using genetically engineered GD2-specific T cells

Andrea Anichini, Malcolm K Brenner, Barbara Savoldo, Michele Del Vecchio, Gianpietro Dotti, Eric S Yvon, Valentina Hoyos, Aurélie Dutour
2009-07-01

Repetitive noninvasive monitoring of HSV1-tk-expressing T cells intravenously infused into nonhuman primates using positron emission tomography and computed tomography with 18F-FEAU

Catherine M Bollard, Barbara Savoldo, Elizabeth J Shpall, Gianpietro Dotti, Laurence J. Cooper, William B Decker, Frank Marini, Juri Gelovani
2009-07-01

Vaccination with agonist peptide PSA: 154-163 (155L) derived from prostate specific antigen induced CD8 T-cell response to the native peptide PSA: 154-163 but failed to induce the reactivity against tumor targets expressing PSA: a phase 2 study in p
2009-05-18

Gene therapy with human and mouse T-cell receptors mediates cancer regression and targets normal tissues expressing cognate antigen

Chyi-Chia R Lee, Nicholas P. Restifo, Alexandria P. Cogdill, Steven Rosenberg, Lydie Cassard, John R Wunderlich, Udai S Kammula, Marybeth S Hughes, Carolyn Laurencot, Susan L Schwarz
2009-04-17

T lymphocytes coexpressing CCR4 and a chimeric antigen receptor targeting CD30 have improved homing and antitumor activity in a Hodgkin tumor model

Biagio De Angelis, Cliona M Rooney, Malcolm K Brenner, Helen Heslop, Barbara Savoldo, Gianpietro Dotti, Aruna Mahendravada
2009-03-25

The promise and potential pitfalls of chimeric antigen receptors
2009-03-03

Genetic manipulation of tumor-specific cytotoxic T lymphocytes to restore responsiveness to IL-7.

Cliona M Rooney, Ann M Leen, Malcolm K Brenner, Helen Heslop, Barbara Savoldo, Gianpietro Dotti, Valentina Hoyos, Greta M P Giordano Attianese, Concetta Quintarelli
2009-02-11

Control of large, established tumor xenografts with genetically retargeted human T cells containing CD28 and CD137 domains

James L. Riley, Carl H. June, Raffit Hassan
2009-01

Noninvasive detection of therapeutic cytolytic T cells with 18F-FHBG PET in a patient with glioma
2009-04-21

Chimeric receptors containing CD137 signal transduction domains mediate enhanced survival of T cells and increased antileukemic efficacy in vivo

James L. Riley, Carl H. June, Stephan A Grupp
2009-04-01

Infusion of suicide-gene-engineered donor lymphocytes after family haploidentical haemopoietic stem-cell transplantation for leukaemia (the TK007 trial): a non-randomised phase I-II study

Luca Vago, Achilles Anagnostopoulos, Paolo Bruzzi, Maria Chiara Bonini, Iacopo Peccatori, marco bregni, Fabio Ciceri, Armando Santoro, Lucia Turchetto, Massimo Bernardi
2009-08-01

Blocking PD-1 in cancer immunotherapy
2008-11-20

The role of indoleamine 2,3-dioxygenase in the induction of immune tolerance: focus on hematology

Michele Baccarani
2008-11

Virus-specific T cells engineered to coexpress tumor-specific receptors: persistence and antitumor activity in individuals with neuroblastoma

Cliona M Rooney, Malcolm K Brenner, Helen Heslop, Barbara Savoldo, M Helen Huls
2008-08-01

Expansion of antileukaemia CTL lines and clones for adoptive cell therapy in paediatric patients given allogeneic haematopoietic stem cell transplantation

Daniela Montagna
2008-10-01

The systematic production of cells for cell therapies

Peter W Zandstra
2008-09

Insertional oncogenesis in 4 patients after retrovirus-mediated gene therapy of SCID-X1

Despina Moshous, Alain Fischer, Marina Cavazzana-Calvo, Salima Hacein-Bey-Abina, Liliane Dal Cortivo, Alexandrine Garrigue, Laure Caccavelli, Uwe Wintergerst, Frederic D. Bushman, Eric Delabesse, Arndt Borkhardt
2008-06-30

Cytotoxic T lymphocytes directed to the preferentially expressed antigen of melanoma (PRAME) target chronic myeloid leukemia

Cliona M Rooney, Helen Heslop, Barbara Savoldo, Gianpietro Dotti, Martha P Mims, Valentina Hoyos, Luigia Luciano, Biagio De Angelis, Concetta Quintarelli
2008-06-29

Establishment of HIV-1 resistance in CD4+ T cells by genome editing using zinc-finger nucleases

Dmitry Guschin, Adam J Waite, Jordan Orange, Philip D Gregory, James L. Riley, Carl H. June, Edward Rebar, Fyodor Urnov
2008-06-23

Administration of rhIL-7 in humans increases in vivo TCR repertoire diversity by preferential expansion of naive T cell subsets

Sarfraz Memon, Michael Krumlauf
2008-05-28

Adoptive immunotherapy for indolent non-Hodgkin lymphoma and mantle cell lymphoma using genetically modified autologous CD20-specific T cells

Ajay K Gopal, Oliver W Press
2008-04-01

TGF-beta and tumors--an ill-fated alliance

Niki Moutsopoulos, Sharon M Wahl
2008-06-01

Antitumor activity of EBV-specific T lymphocytes transduced with a dominant negative TGF-beta receptor

Catherine M Bollard, Cliona M Rooney, Malcolm K Brenner, Helen Heslop, Gianpietro Dotti, Mariam Khalil
2008-05-01

Antigen sensitivity of CD22-specific chimeric TCR is modulated by target epitope distance from the cell membrane

Oliver W Press
2008-05-01

Single and dual amino acid substitutions in TCR CDRs can enhance antigen-specific T cell functions

Steven Rosenberg, Hui Xu, Jennifer Wargo
2008-04-01

Redirecting specificity of T-cell populations for CD19 using the Sleeping Beauty system

Donald B. Kohn, M Helen Huls, Perry B Hackett, Elizabeth J Shpall, Richard E Champlin
2008-04

Adoptive cell transfer: a clinical path to effective cancer immunotherapy

Nicholas P. Restifo, Steven Rosenberg
2008-01-29

Sleeping Beauty transposon-mediated engineering of human primary T cells for therapy of CD19+ lymphoid malignancies

Jakub Tolar, Bruce R Blazar, Carl H. June, Bruce L. Levine, R Scott McIvor
2008

PD-1 and its ligands in tolerance and immunity

Manish J. Butte, Gordon J. Freeman, Arlene Sharpe
2008-01-01

Adoptive transfer of effector CD8+ T cells derived from central memory cells establishes persistent T cell memory in primates
2008-04-01

Loss of CTL function among high-avidity tumor-specific CD8+ T cells following tumor infiltration

Article - wd:Q34188383

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