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The EGF receptor family as targets for cancer therapy

published in: Oncogene

date of publication: 2000-12-01

language: English

Cites articles 80

Date

Title

Authors

2000-02-01

Phase I studies of anti-epidermal growth factor receptor chimeric antibody C225 alone and in combination with cisplatin

Gabriella D'Andrea-Carlino, Larry Norton
2000-03-01

Reversible G(1) arrest induced by inhibition of the epidermal growth factor receptor tyrosine kinase requires up-regulation of p27(KIP1) independent of MAPK activity
2000-04

Inhibitory Fc receptors modulate in vivo cytotoxicity against tumor targets
2000-05-01

ErbB2 potentiates breast tumor proliferation through modulation of p27(Kip1)-Cdk2 complex formation: receptor overexpression does not determine growth dependency
2000-06-01

Induction of apoptosis and activation of the caspase cascade by anti-EGF receptor monoclonal antibodies in DiFi human colon cancer cells do not involve the c-jun N-terminal kinase activity
2000-07-03

The ErbB signaling network: receptor heterodimerization in development and cancer
2000-01-01

Anticancer efficacy of the irreversible EGFr tyrosine kinase inhibitor PD 0169414 against human tumor xenografts
1999-01-01

AKT/PKB and other D3 phosphoinositide-regulated kinases: kinase activation by phosphoinositide-dependent phosphorylation

Tung O. Chan
1999-06-01

Constitutive overexpression of cyclin D1 in human breast epithelial cells does not prevent G1 arrest induced by deprivation of epidermal growth factor

Andrew Koff
1999-09-01

Multinational study of the efficacy and safety of humanized anti-HER2 monoclonal antibody in women who have HER2-overexpressing metastatic breast cancer that has progressed after chemotherapy for metastatic disease
1999-04-29

Neuregulin-4: a novel growth factor that acts through the ErbB-4 receptor tyrosine kinase
1999-04-01

The ErbB-2/HER2 oncoprotein of human carcinomas may function solely as a shared coreceptor for multiple stroma-derived growth factors
1999-08-01

Heregulin regulation of Akt/protein kinase B in breast cancer cells
1999-10-01

Controlled dimerization of ErbB receptors provides evidence for differential signaling by homo- and heterodimers
1999-04-01

Inhibitory effects of combinations of HER-2/neu antibody and chemotherapeutic agents used for treatment of human breast cancers
1999-05-01

Tyrosine kinase inhibitors. 15. 4-(Phenylamino)quinazoline and 4-(phenylamino)pyrido[d]pyrimidine acrylamides as irreversible inhibitors of the ATP binding site of the epidermal growth factor receptor

Jeff Smaill
1999-01-01

Augmentation of a humanized anti-HER2 mAb 4D5 induced growth inhibition by a human-mouse chimeric anti-EGF receptor mAb C225
1998-11-13

Regulation of cell death protease caspase-9 by phosphorylation
1998-09-29

Specific, irreversible inactivation of the epidermal growth factor receptor and erbB2, by a new class of tyrosine kinase inhibitor
1998-04-01

Survival of patients with visceral metastatic melanoma from an occult primary lesion: a retrospective matched cohort study.
1998-03-01

A potent protein-tyrosine kinase inhibitor which selectively blocks proliferation of epidermal growth factor receptor-expressing tumor cells in vitro and in vivo
1998-08-01

Nuclear targeting of Bax during apoptosis in human colorectal cancer cells

Mahitosh Mandal
1998-08-01

Phase II study of receptor-enhanced chemosensitivity using recombinant humanized anti-p185HER2/neu monoclonal antibody plus cisplatin in patients with HER2/neu-overexpressing metastatic breast cancer refractory to chemotherapy treatment.
1998-10-01

Remission of human breast cancer xenografts on therapy with humanized monoclonal antibody to HER-2 receptor and DNA-reactive drugs
1998-01-01

Specificity within the EGF family/ErbB receptor family signaling network
1998-11-01

Overexpression of ErbB2 blocks Taxol-induced apoptosis by upregulation of p21Cip1, which inhibits p34Cdc2 kinase

Ming Tan
1997-06-01

The ErbB signaling network in embryogenesis and oncogenesis: signal diversification through combinatorial ligand-receptor interactions
1997-11-01

Phosphatidylinositol 3-kinase couples the interleukin-2 receptor to the cell cycle regulator E2F
1997-06-01

Neuregulins and their receptors: a versatile signaling module in organogenesis and oncogenesis
1997-10-17

Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery
1997-10-01

Biochemical and antiproliferative properties of 4-[ar(alk)ylamino]pyridopyrimidines, a new chemical class of potent and specific epidermal growth factor receptor tyrosine kinase inhibitor
1997-05-01

A subclass of tumor-inhibitory monoclonal antibodies to ErbB-2/HER2 blocks crosstalk with growth factor receptors

Ronit Pinkas-Kramarski

Article - wd:Q34293543

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