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Discovery of a novel noniminosugar acid α glucosidase chaperone series

author

Wei Zheng

Noel Southall

Leslie Matalonga

Antonia Ribes

Anton Simeonov

Juan Jose Marugan

Ehud Goldin

Omid Motabar

Wendy Westbroek

Arash Velayati

published in: Journal of Medicinal Chemistry

date of publication: 2012-08-17

language: English

main subject: molecular chaperones

Cites articles 28

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Evaluation of quinazoline analogues as glucocerebrosidase inhibitors with chaperone activity

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A new resorufin-based alpha-glucosidase assay for high-throughput screening

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The pharmacological chaperone 1-deoxynojirimycin increases the activity and lysosomal trafficking of multiple mutant forms of acid alpha-glucosidase

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A counterintuitive approach to treat enzyme deficiencies: use of enzyme inhibitors for restoring mutant enzyme activity
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Article - wd:Q34352720

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