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Vasorelaxant effects of novel Kv 7.4 channel enhancers ML213 and NS15370

author

Thomas A Jepps

Bo Hjorth Bentzen

Jennifer B Stott

Oleksandr V Povstyan

Iain A Greenwood

published in: British Journal of Pharmacology

date of publication: 2014-08-14

language: English

Cites articles 46

Date

Title

Authors

2014-01

The IUPHAR/BPS Guide to PHARMACOLOGY: an expert-driven knowledgebase of drug targets and their ligands

Christopher Southan, Adam J Pawson, Joanna L. Sharman, Helen E Benson, Elena Faccenda, Steve Alexander, Anthony P Davenport, Michael Spedding
2014-02-20

Contribution of kv7.4/kv7.5 heteromers to intrinsic and calcitonin gene-related peptide-induced cerebral reactivity.

Iain A Greenwood, Thomas A Jepps, Jennifer B Stott
2013-12-01

The Concise Guide to PHARMACOLOGY 2013/14: ion channels

Steve Alexander, Elena Faccenda, Adam J Pawson, Joanna L. Sharman, Michael Spedding
2013-12-12

K(V)7 potassium channels: a new therapeutic target in smooth muscle disorders

Jennifer B Stott, Thomas A Jepps, Iain A Greenwood
2013-12-02

Differential protein kinase C-dependent modulation of Kv7.4 and Kv7.5 subunits of vascular Kv7 channels

Kenneth L. Byron
2013-01-01

One man's side effect is another man's therapeutic opportunity: targeting Kv7 channels in smooth muscle disorders

Iain A Greenwood
2013-04-03

Characterization of a novel high-potency positive modulator of K(v)7 channels.

Palle Christophersen
2013-09-30

Contribution of Kv7 channels to basal coronary flow and active response to ischemia

Nicole Schmitt, Thomas A Jepps, Bo Hjorth Bentzen, Iain A Greenwood, Søren-Peter Olesen, Ewa Soltysinska
2013-05-21

Bladder contractility is modulated by Kv7 channels in pig detrusor

Julie Svalø, Majid Sheykhzade, Pierre Bouchelouche
2012-06-01

Pharmacological dissection of K(v)7.1 channels in systemic and pulmonary arteries
2012-02-21

Reduced KCNQ4-encoded voltage-dependent potassium channel activity underlies impaired β-adrenoceptor-mediated relaxation of renal arteries in hypertension.
2011-10-19

Discovery, Synthesis, and Structure–Activity Relationship of a Series of N -Aryl-bicyclo[2.2.1]heptane-2-carboxamides: Characterization of ML213 as a Novel KCNQ2 and KCNQ4 Potassium Channel Opener

Craig W. Lindsley
2011-10-01

Driving with no brakes: molecular pathophysiology of Kv7 potassium channels

Maria Virginia Soldovieri, Francesco Miceli
2011-09-30

Kv7 potassium channels in airway smooth muscle cells: signal transduction intermediates and pharmacological targets for bronchodilator therapy

Kenneth L. Byron, Julian Solway
2011-06-28

KV7 channels regulate muscle tone and nonadrenergic noncholinergic relaxation of the rat gastric fundus
2011-09-01

Activation of vascular KCNQ (Kv7) potassium channels reverses spasmogen-induced constrictor responses in rat basilar artery

Bharath K Mani, Kenneth L. Byron
2011-01-01

Expression and function of the K+ channel KCNQ genes in human arteries

Iain A Greenwood, Thomas A Jepps, Andrew Wan, Antonio E Nardi
2011-03-01

The contribution of Kv7 channels to pregnant mouse and human myometrial contractility

Rachel Tribe, Iain A Greenwood
2011-03-30

Randomized, double-blind, placebo-controlled trial of ezogabine (retigabine) in partial epilepsy.

Jacqueline French
2011-09-06

Kv 7 positive modulators reduce detrusor overactivity and increase bladder capacity in rats

Julie Svalø, Majid Sheykhzade
2011-07-11

Downregulation of Kv7.4 channel activity in primary and secondary hypertension

Thomas A Jepps, Søren-Peter Olesen, Iain A Greenwood
2010-08-17

Differential effects of ICA-27243 on cloned K(V)7 channels

Nicole Schmitt, Sigrid Marie Blom
2010-10-13

Efficacy and safety of adjunctive ezogabine (retigabine) in refractory partial epilepsy.
2010-04-10

Functional effects of the KCNQ modulators retigabine and XE991 in the rat urinary bladder

Julie Svalø, Majid Sheykhzade
2010-07-12

Participation of KCNQ (Kv7) potassium channels in myogenic control of cerebral arterial diameter

Iain A Greenwood
2009-04-23

Molecular and functional characterization of Kv7 K+ channel in murine gastrointestinal smooth muscles

Kenton M. Sanders
2009-01-16

KCNQ modulators reveal a key role for KCNQ potassium channels in regulating the tone of rat pulmonary artery smooth muscle
2009-09-03

The KCNQ2/3 selective channel opener ICA-27243 binds to a novel voltage-sensor domain site
2008-06-09

Bimodal effects of the Kv7 channel activator retigabine on vascular K+ currents

Michael Schwake, Iain A Greenwood
2008-02-13

Vascular KCNQ potassium channels as novel targets for the control of mesenteric artery constriction by vasopressin, based on studies in single cells, pressurized arteries, and in vivo measurements of mesenteric vascular resistance

Kenneth L. Byron
2008-11-17

Refinement of the binding site and mode of action of the anticonvulsant Retigabine on KCNQ K+ channels

Wienke Lange, Michael Schwake
2008-08-16

Expression and function of K(v)7 channels in murine myometrium throughout oestrous cycle

Iain A Greenwood, Rachel Tribe

Article - wd:Q34402797

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