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The modular phosphorylation and activation of p70s6k.

author

Nicholas A Pullen

published in: FEBS Letters

date of publication: 1997-06-01

language: English

main subject: phosphorylation

Cites articles 40

Date

Title

Authors

1997-01-01

A specific product of phosphatidylinositol 3-kinase directly activates the protein kinase Akt through its pleckstrin homology domain

David Pot, Lewis T. Williams
1996-07-01

Retinoblastoma protein. Another role rolls in.

Kim Nasmyth
1996-11-01

The principal rapamycin-sensitive p70(s6k) phosphorylation sites, T-229 and T-389, are differentially regulated by rapamycin-insensitive kinase kinases
1996-04-01

Phosphoinositide kinases
1996-11-01

Phosphatidylinositol 3-kinase signals activate a selective subset of Rac/Rho-dependent effector pathways
1996-08-01

Membrane localization of phosphatidylinositol 3-kinase is sufficient to activate multiple signal-transducing kinase pathways

Lewis T. Williams
1996-05-01

The 70 kDa S6 kinase complexes with and is activated by the Rho family G proteins Cdc42 and Rac1.
1996-10-01

Direct inhibition of the signaling functions of the mammalian target of rapamycin by the phosphoinositide 3-kinase inhibitors, wortmannin and LY294002
1996-12-01

Mechanism of activation of protein kinase B by insulin and IGF-1

Dario Alessi, Brian Hemmings
1995-09-01

Rapamycin, wortmannin, and the methylxanthine SQ20006 inactivate p70s6k by inducing dephosphorylation of the same subset of sites
1995-05-01

Multiple independent inputs are required for activation of the p70 S6 kinase
1995-10-01

Control of p70 s6 kinase by kinase activity of FRAP in vivo
1995-10-01

When is a lipid kinase not a lipid kinase? When it is a protein kinase
1995-12-01

Structural and functional analysis of pp70S6k
1995-06-01

Phosphatidylinositol 3-kinase signals activation of p70 S6 kinase in situ through site-specific p70 phosphorylation

Lewis T. Williams
1995-08-17

Protein kinase B (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction
1995-06-02

The protein kinase encoded by the Akt proto-oncogene is a target of the PDGF-activated phosphatidylinositol 3-kinase
1995-10-01

Wortmannin and its structural analogue demethoxyviridin inhibit stimulated phospholipase A2 activity in Swiss 3T3 cells. Wortmannin is not a specific inhibitor of phosphatidylinositol 3-kinase

Michael Wakelam
1995-12-01

Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B

Dario Alessi, Brian Hemmings
1995-11-01

The principal target of rapamycin-induced p70s6k inactivation is a novel phosphorylation site within a conserved hydrophobic domain

Nicholas A. Williamson, Rick Pearson
1995-03-01

Normal activation of p70 S6 kinase by insulin in cells overexpressing dominant negative 85kD subunit of phosphoinositide 3-kinase
1994-11-01

Mitogenesis and protein synthesis: a role for ribosomal protein S6 phosphorylation?
1994-09-01

Activation of p70/p85 S6 kinase by a pathway independent of p21ras
1994-07-01

Phosphatidylinositol 3-kinase activation is required for insulin stimulation of pp70 S6 kinase, DNA synthesis, and glucose transporter translocation

C. Ronald Kahn
1994-06-30

A mammalian protein targeted by G1-arresting rapamycin-receptor complex
1994-07-07

PDGF- and insulin-dependent pp70S6k activation mediated by phosphatidylinositol-3-OH kinase
1994-08-02

1-Phosphatidylinositol 3-kinase activity is required for insulin-stimulated glucose transport but not for RAS activation in CHO cells

Kenta Hara
1994-11-01

The growth of research on protein phosphorylation
1994-04-01

Nuclear localization of p85s6k: functional requirement for entry into S phase
1993-05-01

p70s6k function is essential for G1 progression
1992-06-26

Rapamycin-FKBP specifically blocks growth-dependent activation of and signaling by the 70 kd S6 protein kinases
1992-08-01

Rapamycin-induced inhibition of the 70-kilodalton S6 protein kinase

Barbara Bierer

Article - wd:Q34434557

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