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Why is p53 acetylated?

published in: Cell

date of publication: 2001-12-01

language: English

Cites articles 18

Date

Title

Authors

2001-12-01

Acetylation of p53 activates transcription through recruitment of coactivators/histone acetyltransferases

Shelley L. Berger
2001-02-01

Inhibition of p53-dependent transcription by BOX-I phospho-peptide mimetics that bind to p300.
2001-07-01

Transcriptional regulation by p53 through intrinsic DNA/chromatin binding and site-directed cofactor recruitment.
2001-03-01

p300/CBP-mediated p53 acetylation is commonly induced by p53-activating agents and inhibited by MDM2.
2001-02-01

Regulation of p53 by hypoxia: dissociation of transcriptional repression and apoptosis from p53-dependent transactivation

Costas Koumenis, Maureen Murphy
2001-10-19

Negative control of p53 by Sir2alpha promotes cell survival under stress
2001-10-19

hSIR2(SIRT1) functions as an NAD-dependent p53 deacetylase

Robert Weinberg
2000-07-07

Histone deacetylases specifically down-regulate p53-dependent gene activation
2000-11-01

MDM2 inhibits p300-mediated p53 acetylation and activation by forming a ternary complex with the two proteins
2000-11-16

Deacetylation of p53 modulates its effect on cell growth and apoptosis
2000-12-01

Multiple lysine mutations in the C-terminal domain of p53 interfere with MDM2-dependent protein degradation and ubiquitination
2000-08-17

Atmospheric carbon dioxide concentrations over the past 60 million years
1999-12-01

Serine15 phosphorylation stimulates p53 transactivation but does not directly influence interaction with HDM2.
1999-02

p53 sites acetylated in vitro by PCAF and p300 are acetylated in vivo in response to DNA damage
1999-10-01

Transcriptional repression by wild-type p53 utilizes histone deacetylases, mediated by interaction with mSin3a

Maureen Murphy, Ronald M. Evans
1998-12-01

Phosphorylation of p53 serine 15 increases interaction with CBP
1998-09-15

DNA damage activates p53 through a phosphorylation-acetylation cascade
1997-08-22

Activation of p53 sequence-specific DNA binding by acetylation of the p53 C-terminal domain

Article - wd:Q34486036

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