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The primary function of RNA binding by the influenza A virus NS1 protein in infected cells: Inhibiting the 2'-5' oligo (A) synthetase/RNase L pathway

published in: Proceedings of the National Academy of Sciences of the United States of America

date of publication: 2006-04-20

language: English

main subject: virus, influenza A virus

Cites articles 36

Date

Title

Authors

2006-04-01

The CPSF30 binding site on the NS1A protein of influenza A virus is a potential antiviral target.

Diana L. Noah
2005-08-01

Influenza: lessons from past pandemics, warnings from current incidents.

Yoshihiro Kawaoka
2005-01-01

Influenza virus virulence and its molecular determinants

Diana L. Noah
2004-01-26

Interferon antagonist proteins of influenza and vaccinia viruses are suppressors of RNA silencing

Peter Palese, Adolfo García-Sastre, Monica Dus
2004-02-01

Biophysical characterization of the complex between double-stranded RNA and the N-terminal domain of the NS1 protein from influenza A virus: evidence for a novel RNA-binding mode

Gaetano T. Montelione
2003-12-01

A recombinant influenza A virus expressing an RNA-binding-defective NS1 protein induces high levels of beta interferon and is attenuated in mice

Christopher F Basler, Adolfo García-Sastre
2003-11

Crystal structure of the 2'-specific and double-stranded RNA-activated interferon-induced antiviral protein 2'-5'-oligoadenylate synthetase

Saumendra N Sarkar, Rune Hartmann
2003-05-01

Intracellular warfare between human influenza viruses and human cells: the roles of the viral NS1 protein

Diana L. Noah
2003-03-15

Cellular antiviral responses against influenza A virus are countered at the posttranscriptional level by the viral NS1A protein via its binding to a cellular protein required for the 3' end processing of cellular pre-mRNAS

Diana L. Noah
2002-12-01

Functional replacement of the carboxy-terminal two-thirds of the influenza A virus NS1 protein with short heterologous dimerization domains

Peter Palese, Christopher F Basler, Bryan R Williams, Adolfo García-Sastre, Robert H. Silverman
2002-10-24

Replicating hepatitis delta virus RNA is edited in the nucleus by the small form of ADAR1.
2002-11-01

The influenza A virus NS1 protein inhibits activation of Jun N-terminal kinase and AP-1 transcription factors

Adolfo García-Sastre, Stephan Ludwig, Stephan Pleschka, Nicola Donelan, Hongyong Zheng
2002-07-11

Human influenza viruses activate an interferon-independent transcription of cellular antiviral genes: outcome with influenza A virus is unique
2002-02-01

Effects of influenza A virus NS1 protein on protein expression: the NS1 protein enhances translation and is not required for shutoff of host protein synthesis

Mirella Salvatore, Christopher F Basler, Peter Palese, Adolfo García-Sastre
2001-01-01

The 1918 Spanish influenza: integrating history and biology.

Jeffery Taubenberger, Thomas Fanning, Ann H. Reid
2001-01-01

Inhibition of interferon-mediated antiviral responses by influenza A viruses and other negative-strand RNA viruses

Adolfo García-Sastre
2000-12-27

Functional characterization of and cooperation between the double-stranded RNA-binding motifs of the protein kinase PKR

B Tian
2000-12-01

Influenza A virus NS1 protein prevents activation of NF-kappaB and induction of alpha/beta interferon

Peter Palese, Adolfo García-Sastre
2000-04-01

Novel functions of interferon-induced proteins
2000-09-01

Activation of interferon regulatory factor 3 is inhibited by the influenza A virus NS1 protein

Peter Palese, Christopher F Basler, Adolfo García-Sastre
2000-03-01

RNA recognition by a Staufen double-stranded RNA-binding domain

Alejandra Ramos, David R Micklem
1999-04-01

In or out? Regulating nuclear transport
1999-04-01

Influenza A virus NS1 protein targets poly(A)-binding protein II of the cellular 3'-end processing machinery
1999-02-01

RNA binding by the novel helical domain of the influenza virus NS1 protein requires its dimer structure and a small number of specific basic amino acids
1998-12-01

Molecular basis of double-stranded RNA-protein interactions: structure of a dsRNA-binding domain complexed with dsRNA.
1998-09-01

Structure of the double-stranded RNA-binding domain of the protein kinase PKR reveals the molecular basis of its dsRNA-mediated activation
1998-06-01

Influenza virus NS1 protein interacts with the cellular 30 kDa subunit of CPSF and inhibits 3'end formation of cellular pre-mRNAs
1997-11

Crystal structure of the unique RNA-binding domain of the influenza virus NS1 protein

Helen M. Berman
1997-11-01

A novel RNA-binding motif in influenza A virus non-structural protein 1

Roberto Tejero
1997-11-01

Interferon action and apoptosis are defective in mice devoid of 2',5'-oligoadenylate-dependent RNase L
1995-11-01

An amino-terminal polypeptide fragment of the influenza virus NS1 protein possesses specific RNA-binding activity and largely helical backbone structure
1995-12-01

Binding of the influenza virus NS1 protein to double-stranded RNA inhibits the activation of the protein kinase that phosphorylates the elF-2 translation initiation factor.

Article - wd:Q34598589

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