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The role of apolipoprotein E in Alzheimer's disease

author

David M. Holtzman

1961 -

published in: Neuron

date of publication: 2009-08-01

language: English

main subject: Alzheimer's disease

Cites articles 200

Too many entities requested (239). Only 200 are displayed.

Date

Title

Authors

2009-04-03

Fibrillar amyloid-beta burden in cognitively normal people at 3 levels of genetic risk for Alzheimer's disease

Howard J Aizenstein, William E. Klunk, Kewei Chen, Eric M. Reiman, Steven T. DeKosky, Gene E. Alexander
2009-03-01

APOE epsilon2 is associated with intact cognition but increased Alzheimer pathology in the oldest old.

Maria M Corrada
2009-07-01

Binding and uptake of A beta1-42 by primary human astrocytes in vitro

Sabina Janciauskiene
2009-05-01

Human APOE isoform-dependent effects on brain beta-amyloid levels in PDAPP transgenic mice
2008-12-14

Human apolipoprotein A-I binds amyloid-beta and prevents Abeta-induced neurotoxicity

Lea T Grinberg, María Alejandra Tricerri, Sérgio Teixeira Ferreira, Jordano Brito-Moreira, Theresa R Bomfim
2008-11-01

Loss of LR11/SORLA enhances early pathology in a mouse model of amyloidosis: evidence for a proximal role in Alzheimer's disease

Olav M. Andersen, Thomas E Willnow
2008-07-28

Alzheimer's disease and vascular dementia in developing countries: prevalence, management, and risk factors

Anders Wimo, José A Luchsinger, Martin Prince, Robert Stewart, Kathleen S. Hall
2008-06-12

ApoE promotes the proteolytic degradation of Abeta

Peter Tontonoz, David M. Holtzman
2008-04-01

Multiple SNPs within and surrounding the apolipoprotein E gene influence cerebrospinal fluid apolipoprotein E protein levels

Charles DeCarli, Martin R. Farlow
2008-04-09

APOE epsilon 4 allele predicts faster cognitive decline in mild Alzheimer disease

Jason Brandt, Yaakov Stern, Nikolaos Scarmeas, Stephanie Cosentino
2008-04-01

Endocytosis is required for synaptic activity-dependent release of amyloid-beta in vivo

Jiyeon Lee, Steven Mennerick, David M. Holtzman
2008-01-01

The two faces of protein misfolding: gain- and loss-of-function in neurodegenerative diseases

Jorg Tatzelt, Christian Haass, Konstanze Winklhofer
2008-01-24

The blood-brain barrier in health and chronic neurodegenerative disorders
2008-02-01

Overexpression of ABCA1 reduces amyloid deposition in the PDAPP mouse model of Alzheimer disease

Jungsu Kim, Sanjay Jain, David M. Holtzman
2008-11-13

apoE isoform-specific disruption of amyloid beta peptide clearance from mouse brain

David M. Holtzman, Rashid Deane
2008-11-01

Loss of gamma-secretase function impairs endocytosis of lipoprotein particles and membrane cholesterol homeostasis.

Dietmar R. Thal, Ilse Dewachter, Peter Henry St George-Hyslop, Jochen Walter
2008-11-01

Impact of apolipoprotein E (ApoE) polymorphism on brain ApoE levels
2008-06-17

Clusterin expression during fetal and postnatal CNS development in mouse

Panteleimon Giannakopoulos, Aurélien Lathuilière
2008-05-18

Middle-aged human apoE4 targeted-replacement mice show retention deficits on a wide range of spatial memory tasks.
2008-02-21

Structural and quantitative comparison of cerebrospinal fluid glycoproteins in Alzheimer's disease patients and healthy individuals.

Lars-Olof Wahlund, Magnus Sjögren
2007-12-01

Detrimental effects of apolipoprotein E4: potential therapeutic targets in Alzheimer's disease
2007-12-21

APOE genotype-specific differences in the innate immune response

Candice M Brown, Carol A. Colton
2007-12-08

Sex-dependent association of a common low-density lipoprotein receptor polymorphism with RNA splicing efficiency in the brain and Alzheimer's disease

Dennis W. Dickson, David A Bennett, Ronald C. Petersen
2007-10-04

Amyloid precursor protein regulates brain apolipoprotein E and cholesterol metabolism through lipoprotein receptor LRP1
2007-10-01

Cerebral clearance of human amyloid-beta peptide (1-40) across the blood-brain barrier is reduced by self-aggregation and formation of low-density lipoprotein receptor-related protein-1 ligand complexes

Sumio Ohtsuki, Tetsuya Terasaki, Shingo Ito, Yasuko Nezu, Junichi Kamiie
2007-08-01

Versatility in ligand recognition by LDL receptor family proteins: advances and frontiers
2007-09-12

SorLA/LR11 regulates processing of amyloid precursor protein via interaction with adaptors GGA and PACS-1

Olav M. Andersen, Thomas E Willnow
2007-12-01

Neuronal LR11/sorLA expression is reduced in mild cognitive impairment

Elliott J Mufson, Sue Leurgans
2007-07-09

ApoER2 expression increases Abeta production while decreasing Amyloid Precursor Protein (APP) endocytosis: Possible role in the partitioning of APP into lipid rafts and in the regulation of gamma-secretase activity

Rodrigo A Fuentealba
2007-04-12

Apolipoprotein E levels in cerebrospinal fluid and the effects of ABCA1 polymorphisms

Alison Goate, David M. Holtzman, Anne M Fagan, John S. K. Kauwe, Suzanne E Wahrle, Scott Smemo, Andrew Grupe
2007-04-01

Apolipoprotein receptor 2 and X11 alpha/beta mediate apolipoprotein E-induced endocytosis of amyloid-beta precursor protein and beta-secretase, leading to amyloid-beta production
2007-02

Soluble protein oligomers in neurodegeneration: lessons from the Alzheimer's amyloid beta-peptide

Christian Haass, Dennis J. Selkoe

Article - wd:Q34603092

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