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A Gsalpha mutant designed to inhibit receptor signaling through Gs.

author

Henry R. Bourne

published in: Proceedings of the National Academy of Sciences of the United States of America

date of publication: 1999-01-01

language: English

Cites articles 42

Date

Title

Authors

1998-10-01

Second site suppressor mutations of a GTPase-deficient G-protein alpha-subunit. Selective inhibition of Gbeta gamma-mediated signaling
1998-08-21

The A326S mutant of Gialpha1 as an approximation of the receptor-bound state
1998-07-01

G-protein diseases furnish a model for the turn-on switch.

Henry R. Bourne, Zvi Farfel
1998-01-09

The many faces of G protein signaling
1997-12-01

Receptors induce chemotaxis by releasing the betagamma subunit of Gi, not by activating Gq or Gs

Henry R. Bourne
1997

G protein mechanisms: insights from structural analysis
1997-05-27

Conditional activation defect of a human Gsalpha mutant

Zvi Farfel
1997-01-01

G protein beta gamma subunits

David E Clapham
1997-04-01

How receptors talk to trimeric G proteins
1997-02

Pheromone signalling and polarized morphogenesis in yeast
1997-05-01

RGS4 inhibits Gq-mediated activation of mitogen-activated protein kinase and phosphoinositide synthesis
1996-12-01

Reciprocal regulation of Gs alpha by palmitate and the beta gamma subunit

Henry R. Bourne
1995-02-01

Functional analysis of a dominant negative mutant of G alpha i2.
1995-09-01

Transducin-alpha C-terminal mutations prevent activation by rhodopsin: a new assay using recombinant proteins expressed in cultured cells
1995-05-01

The guanine-nucleotide-binding protein subunit G alpha i2 is involved in calcium activation of phospholipase A2. Effects of the dominant negative G alpha i2 mutant, [G203T]G alpha i2, on activation of phospholipase A2 in Chinese hamster ovary cells
1994-06-01

Ras-dependent activation of MAP kinase pathway mediated by G-protein beta gamma subunits

Piero Crespo, J. Silvio Gutkind
1994-03-01

cAMP and beta gamma subunits of heterotrimeric G proteins stimulate the mitogen-activated protein kinase pathway in COS-7 cells
1994-09-01

Rapid GDP release from Gs alpha in patients with gain and loss of endocrine function

Henry R. Bourne
1994-04-01

The active role of beta gamma in signal transduction
1993-12-16

The 2.2 A crystal structure of transducin-alpha complexed with GTP gamma S
1993-10-14

A constitutively activating mutation of the luteinizing hormone receptor in familial male precocious puberty
1993-10-01

Random mutagenesis of G protein alpha subunit G(o)alpha. Mutations altering nucleotide binding

Anna M Aragay, Henry Lester
1993-07-01

Type II adenylylcyclase integrates coincident signals from Gs, Gi, and Gq

Henry R. Bourne
1992-01-01

The G226A mutant of Gs alpha highlights the requirement for dissociation of G protein subunits
1992-01-01

Recombinant Gq alpha. Mutational activation and coupling to receptors and phospholipase C

Henry R. Bourne, Olivier Chabre
1992-12-01

Activation of the alpha subunit of Gs in intact cells alters its abundance, rate of degradation, and membrane avidity
1991-01-10

The GTPase superfamily: conserved structure and molecular mechanism
1991-05-01

Mutant α subunits of Gi2 inhibit cyclic AMP accumulation

Jacques Pouysségur, Henry R. Bourne
1991-03-01

A dominant negative G alpha s mutant is rescued by secondary mutation of the alpha chain amino terminus
1991-12-01

Activating and inactivating mutations of the alpha subunit of Gi2 protein have opposite effects on proliferation of NIH 3T3 cells

J. Silvio Gutkind
1991-10-01

A mutation in the putative Mg(2+)-binding site of Gs alpha prevents its activation by receptors
1991-06-01

Stoichiometry of receptor‐G s ‐adenylate cyclase interactions

Article - wd:Q34817858

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