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A CK2-dependent mechanism for activation of the JAK-STAT signaling pathway

著者

Ayalew Tefferi

この作品が含まれる作品: Blood

出版日: 2011-04-28

言語: 英語

Cites articles 48

Date

タイトル

著者

2009-12-01

The JAK2 inhibitor AZD1480 potently blocks Stat3 signaling and oncogenesis in solid tumors
2009-11

STATs in cancer inflammation and immunity: a leading role for STAT3
2009-10-14

Cotreatment with panobinostat and JAK2 inhibitor TG101209 attenuates JAK2V617F levels and signaling and exerts synergistic cytotoxic effects against human myeloproliferative neoplastic cells

Atul D. Joshi
2009-04-13

Regulation of Jak2 function by phosphorylation of Tyr317 and Tyr637 during cytokine signaling
2009-08

CYT387, a selective JAK1/JAK2 inhibitor: in vitro assessment of kinase selectivity and preclinical studies using cell lines and primary cells from polycythemia vera patients

Ayalew Tefferi
2009-02-01

Phospho-regulated SUMO interaction modules connect the SUMO system to CK2 signaling
2008-07-06

Protein kinase CK2 catalyzes tyrosine phosphorylation in mammalian cells

Lorenzo A Pinna, Stefania Sarno
2008-03-11

Transgenic expression of JAK2V617F causes myeloproliferative disorders in mice

Shu Xing
2008-06-14

The emerging CK2 interactome: insights into the regulation and functions of CK2.
2008-02-07

An unbiased evaluation of CK2 inhibitors by chemoproteomics: characterization of inhibitor effects on CK2 and identification of novel inhibitor targets.

Maria Bretner
2008-09-01

Myeloproliferative disorders
2007-10-22

The alpha catalytic subunit of protein kinase CK2 is required for mouse embryonic development

Dominguez I
2007-08-30

Too much of a good thing: the role of protein kinase CK2 in tumorigenesis and prospects for therapeutic inhibition of CK2.
2007-09-20

JAK2 inhibitor therapy in myeloproliferative disorders: rationale, preclinical studies and ongoing clinical trials
2007-09-01

Role of JAK2 in the pathogenesis and therapy of myeloproliferative disorders

Ayalew Tefferi
2007-05-08

Determinants of growth hormone receptor down-regulation

Stuart J Frank
2007-02-01

Protein kinase CK2alpha as an unfavorable prognostic marker and novel therapeutic target in acute myeloid leukemia

Jin Seok Kim, June-Won Cheong, Yoo Hong Min
2007-01-02

Tetrabromocinnamic Acid (TBCA) and Related Compounds Represent a New Class of Specific Protein Kinase CK2 Inhibitors

Giovanni Di Maira, Giorgio Cozza, Mario A Pagano, Maria Ruzzene, Lorenzo A Pinna, Stefano Moro, Stefania Sarno
2006-12-01

Characterization of murine JAK2V617F-positive myeloproliferative disease

ブライアン・ドラッカー, Lisa J. Wood
2006-11-22

The promyelocytic leukemia protein functions as a negative regulator of IFN-gamma signaling

ピエール・パオロ・パンドルフィ
2006-07-28

A CK2-dependent mechanism for degradation of the PML tumor suppressor

Hediye Erdjument-Bromage, Paul Tempst, ピエール・パオロ・パンドルフィ, Julie Teruya-Feldstein, Pier Paolo Scaglioni
2006-05-02

JAK2V617F expression in murine hematopoietic cells leads to MPD mimicking human PV with secondary myelofibrosis

Didier Pisani, William Vainchenker, Jean-Luc Villeval
2006-02-23

Janus kinase 2 influences growth hormone receptor metalloproteolysis

Stuart J Frank
2006-01-01

Divergent effects of oncostatin M on astroglioma cells: influence on cell proliferation, invasion, and expression of matrix metalloproteinases
2006-05-09

Multiple myeloma cell survival relies on high activity of protein kinase CK2.

フランチェスコ・ピアッツァ, Maria Ruzzene, Giovanni Di Maira, Lorenzo A Pinna, Livio Trentin, Gianpietro Semenzato
2006-11-02

Treatment of P190 Bcr/Abl lymphoblastic leukemia cells with inhibitors of the serine/threonine kinase CK2

Lorenzo A Pinna
2006-12-01

IL-10 inhibits lipopolysaccharide-induced CD40 gene expression through induction of suppressor of cytokine signaling-3
2005-06-01

CK2 as a positive regulator of Wnt signalling and tumourigenesis
2005-11-01

Targeting CK2 for cancer therapy

Gretchen M Unger
2005-04-01

A gain-of-function mutation of JAK2 in myeloproliferative disorders

Robert Kralovics, Francesco Passamonti, Jakob R. Passweg
2005-04-01

Activating mutation in the tyrosine kinase JAK2 in polycythemia vera, essential thrombocythemia, and myeloid metaplasia with myelofibrosis

Jan Cools, Brian Huntly, Peter Vandenberghe, Stacey Gabriel, Todd Golub, Titus J Boggon, Stephanie J. Lee
2005-04-01

A unique clonal JAK2 mutation leading to constitutive signalling causes polycythaemia vera

William Vainchenker, Francois Delhommeau, Hana Raslova, Annelise Bennaceur Griscelli, Jean-Luc Villeval, Stefan N Constantinescu

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