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Regulation of cell surface transferrin receptor-2 by iron-dependent cleavage and release of a soluble form.

auteur·ice

Antonella Nai

Laura Silvestri

publié dans: Haematologica

date de publication: 2015-01-30

Articles cités 33

Date

Titre

Auteur·ices

2014-12-11

The second transferrin receptor regulates red blood cell production in mice

Antonella Nai, Alessia Pagani, Laura Silvestri
2014-03-21

The erythroid function of transferrin receptor 2 revealed by Tmprss6 inactivation in different models of transferrin receptor 2 knockout mice

Antonella Nai, Laura Silvestri, Giuseppe Saglio, Antonella Roetto
2013-10-14

In situ proximity ligation assays indicate that hemochromatosis proteins Hfe and transferrin receptor 2 (Tfr2) do not interact

Gautam Rishi, Daniel F. Wallace, Nathan V Subramaniam, Emily M Crampton
2013-05-15

Implication of the proprotein convertases in iron homeostasis: proprotein convertase 7 sheds human transferrin receptor 1 and furin activates hepcidin.

Johann Guillemot, Nabil Seidah, Annik Prat
2012-11

The hemochromatosis proteins HFE, TfR2, and HJV form a membrane-associated protein complex for hepcidin regulation

Matthias Hentze, Martina U Muckenthaler
2011-08-16

Hereditary hemochromatosis and transferrin receptor 2
2011-04

A time course of hepcidin response to iron challenge in patients with HFE and TFR2 hemochromatosis

Clara Camaschella, Domenico Girelli, Tomas Ganz
2010-12-10

Novel association to the proprotein convertase PCSK7 gene locus revealed by analysing soluble transferrin receptor (sTfR) levels

Caroline Hayward, Irene Pichler, Christian Gieger, Thomas Meitinger, Bertram Müller-Myhsok, Konrad Oexle, Igor Rudan, Angela Döring, Thomas Illig, Andrew A Hicks, Juliane Winkelmann, Joachim Thiery, Luigi Ferrucci, Peter Lichtner, Stefania Bandinelli, Heinz Erich Wichmann, Harry Campbell, Toshiko Tanaka, Cosetta Minelli, Peter P. Pramstaller, Janina S Ried, Christine Schwienbacher, Martin Gögele, Georg Martin Fiedler
2010-09-08

Transferrin receptor 2 is a component of the erythropoietin receptor complex and is required for efficient erythropoiesis

Murielle Gaudry
2010-02-23

Comparison of 3 Tfr2-deficient murine models suggests distinct functions for Tfr2-alpha and Tfr2-beta isoforms in different tissues

Emilio Hirsch, Giuseppe Saglio, Ferdinando Di Cunto, Fulvio Riondato
2009-12-01

Combined deletion of Hfe and transferrin receptor 2 in mice leads to marked dysregulation of hepcidin and iron overload

Daniel F. Wallace, David M. Frazer, Gregory J Anderson, Nathan V Subramaniam, Lesa Summerville, Emily M Crampton
2008-10-01

Hemojuvelin N-terminal mutants reach the plasma membrane but do not activate the hepcidin response
2008-01-15

Furin-mediated release of soluble hemojuvelin: a new link between hypoxia and iron homeostasis

Clara Camaschella, Laura Silvestri
2008

Soluble hemojuvelin is released by proprotein convertase-mediated cleavage at a conserved polybasic RNRR site

Tomas Ganz
2008-11-01

Serum transferrin receptor
2007-05-02

The molecular mechanism of hepcidin-mediated ferroportin down-regulation

Tomas Ganz
2006-12-20

Transferrin receptor 2: evidence for ligand-induced stabilization and redirection to a recycling pathway

Martha B Johnson
2006-04-09

Bone morphogenetic protein signaling by hemojuvelin regulates hepcidin expression

Yin Xia, Nancy Andrews, Raymond T Chung
2005-12-14

Release of the soluble transferrin receptor is directly regulated by binding of its ligand ferritransferrin
2005-07-01

First phenotypic description of transferrin receptor 2 knockout mouse, and the role of hepcidin

Daniel F. Wallace, Nathan V Subramaniam
2004-08-19

Diferric transferrin regulates transferrin receptor 2 protein stability

Martha B Johnson
2004-10-14

Hepcidin is decreased in TFR2 hemochromatosis

Tomas Ganz, Antonella Roetto
2004-11-01

Analyses for binding of the transferrin family of proteins to the transferrin receptor 2
2003-03-01

Soluble transferrin receptor for the evaluation of erythropoiesis and iron status
2001-11-01

Expression of transferrin receptor 2 in normal and neoplastic hematopoietic cells
2001-09-01

Regulation of expression of murine transferrin receptor 2.
2000-05-01

The gene TFR2 is mutated in a new type of haemochromatosis mapping to 7q22.

Massimo Carella, Marco De Gobbi
2000-06-02

Transferrin receptor 2-alpha supports cell growth both in iron-chelated cultured cells and in vivo
2000-02-29

Transferrin receptor 2: continued expression in mouse liver in the face of iron overload and in hereditary hemochromatosis
1999-07-23

Molecular cloning of transferrin receptor 2. A new member of the transferrin receptor-like family
1998-12-01

Redundant and distinct functions for dynamin-1 and dynamin-2 isoforms
1997-08-01

The trans-Golgi network: a late secretory sorting station

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