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Amyloid β oligomers in Alzheimer's disease pathogenesis, treatment, and diagnosis

author

William L. Klein

published in: Acta Neuropathologica

date of publication: 2015-01-22

main subject: pathogenesis, Alzheimer's disease

Cites articles 194

Date

Title

Authors

2015-04-30

Nanoscale Synaptic Membrane Mimetic Allows Unbiased High Throughput Screen That Targets Binding Sites for Alzheimer's-Associated Aβ Oligomers

Michael Marty, Benjamin D Kuhns, William L. Klein
2015-01-01

Cognitive and functional decline and their relationship in patients with mild Alzheimer's dementia

Jeffrey L. Cummings, Paul S. Aisen
2015-01-01

The murine version of BAN2401 (mAb158) selectively reduces amyloid-β protofibrils in brain and cerebrospinal fluid of tg-ArcSwe mice

Lars Lannfelt
2014-12-22

Towards non-invasive diagnostic imaging of early-stage Alzheimer's disease

Emily A Waters, William L. Klein
2014-11-12

Alzheimer's therapeutics targeting amyloid beta 1-42 oligomers II: Sigma-2/PGRMC1 receptors mediate Abeta 42 oligomer binding and synaptotoxicity

Nicholas J. Izzo, Michael A. Cahill, Carlos Cruchaga, Tara L Spires-Jones, Alison Goate, Ottavio Arancio, Robert H Mach
2014

Alzheimer's therapeutics targeting amyloid beta 1-42 oligomers I: Abeta 42 oligomer binding to specific neuronal receptors is displaced by drug candidates that improve cognitive deficits

Nicholas J. Izzo, Mauro Fà, Conrad Johanson, Ottavio Arancio
2014-10-03

Immunotherapy alleviates amyloid-associated synaptic pathology in an Alzheimer's disease mouse model

Mario Dorostkar, Boris Schmidt, Jochen Herms, Steffen Burgold, Severin Filser
2014-09-12

Lost after translation: missorting of Tau protein and consequences for Alzheimer disease

Eckhard Mandelkow
2014-06-28

Type 3 diabetes is sporadic Alzheimer׳s disease: mini-review
2014

Targeting the proper amyloid-beta neuronal toxins: a path forward for Alzheimer's disease immunotherapeutics
2014-03-24

Perspectives on future Alzheimer therapies: amyloid-β protofibrils - a new target for immunotherapy with BAN2401 in Alzheimer's disease

Dag Sehlin, Lars Lannfelt
2014-05-27

Intracellular processing of disease-associated α-synuclein in the human brain suggests prion-like cell-to-cell spread.

Gabor G Kovacs, Leonid Breydo, Péter Lőrincz, Herbert Budka, Kinga Molnar, Lajos László
2014-05-02

6-Shogaol, an active constituent of ginger, attenuates neuroinflammation and cognitive deficits in animal models of dementia
2014-04-23

Aminostyrylbenzofuran directly reduces oligomeric amyloid-β and reverses cognitive deficits in Alzheimer transgenic mice
2014-07

Structural evolution and membrane interactions of Alzheimer's amyloid-beta peptide oligomers: new knowledge from single-molecule fluorescence studies

Duncan G. Steel
2014-04-16

Do astrocytes collaborate with neurons in spreading the "infectious" aβ and Tau drivers of Alzheimer's disease?

Ilaria Pierpaola Dal Prà, Anna Chiarini, Emanuela Gardenal
2014-04-13

Gly25-Ser26 amyloid β-protein structural isomorphs produce distinct Aβ42 conformational dynamics and assembly characteristics

Xueyun Zheng, George Benedek
2014-04-08

Tau-based therapeutic approaches for Alzheimer's disease - a mini-review

Thomas Wisniewski
2014-04-09

Rare individual amyloid-β oligomers act on astrocytes to initiate neuronal damage

Kira Holmström, David Klenerman, Daniel J. Whitcomb, Kwangwook Cho, Mark R. Wilson, Andrey Y Abramov, Peter Henry St George-Hyslop, Nicholas W. Wood, Chris Dobson, Priyanka Narayan
2014-01-01

Tissue transglutaminase in Alzheimer's disease: involvement in pathogenesis and its potential as a therapeutic target

Benjamin Drukarch
2014-01-01

Plasma membrane injury depends on bilayer lipid composition in Alzheimer's disease

Roberta Cascella, Anna Caselli, Claudia Fiorillo, Matteo Becatti, Cristina Cecchi, Benedetta Nacmias
2014-03-06

Apolipoprotein E receptor pathways in Alzheimer disease

Thomas E Willnow
2014-02-01

How does brain insulin resistance develop in Alzheimer's disease?

Mychael V Lourenco, Sérgio Teixeira Ferreira, Fernanda De Felice
2014-02-05

Atomic force microscopy to study molecular mechanisms of amyloid fibril formation and toxicity in Alzheimer's disease

Brenda Y Lee
2014-01-23

Environmental enrichment strengthens corticocortical interactions and reduces amyloid-β oligomers in aged mice

Marco Mainardi, Matteo Caleo, Alessandro Sale, Lamberto Maffei
2014-01-09

Spreading of amyloid-β peptides via neuritic cell-to-cell transfer is dependent on insufficient cellular clearance

Lotta Agholme, Martin Hallbeck
2014-01-01

Structural diversity of Alzheimer's disease amyloid-β dimers and their role in oligomerization and fibril formation

Igor Tsigelny, Paula Desplats, Valentina L Kouznetsova, Eliezer Masliah
2014-01-01

Pan-amyloid oligomer specific scFv antibody attenuates memory deficits and brain amyloid burden in mice with Alzheimer's disease
2014

Cellular prion protein as a therapeutic target in Alzheimer's disease
2014-01-01

Conformation-specific antibodies to target amyloid β oligomers and their application to immunotherapy for Alzheimer's disease
2014-05-23

Factors influencing compact-extended structure equilibrium in oligomers of aβ1-40 peptide--an ion mobility mass spectrometry study.

Jarosław Poznański, Michał Dadlez, Wojciech Bal
2014-04-23

Significant structural differences between transient amyloid-β oligomers and less-toxic fibrils in regions known to harbor familial Alzheimer's mutations

Sudipta Maiti, Bidyut Sarkar

Article - wd:Q35327172

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