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Proteasome inhibition enhances the killing effect of BikDD gene therapy

author

Mariano Ponz-Sarvise

published in: American Journal of Translational Research

date of publication: 2015-02-15

language: English

main subject: gene therapy

Cites articles 27

Date

Title

Authors

2014-04-30

Targeted BikDD expression kills androgen-dependent and castration-resistant prostate cancer cells

Xiaoming Xie, Yanan Kong, Mien-Chie Hung
2014-03-17

BikDDA, a mutant of Bik with longer half-life expression protein, can be a novel therapeutic gene for triple-negative breast cancer
2012-07-02

Targeted expression of BikDD eliminates breast cancer with virtually no toxicity in noninvasive imaging models

Yanan Kong, Xiaoming Xie, Mien-Chie Hung, Jiaoli Guo
2011-09-01

BikDD eliminates breast cancer initiating cells and synergizes with lapatinib for breast cancer treatment

Xiaoming Xie, Wendy A Woodward, Funda Meric-Bernstam, Gabriel N Hortobagyi, Mien-Chie Hung
2011-01-31

Cancer-targeted BikDD gene therapy elicits protective antitumor immunity against lung cancer

Mien-Chie Hung, Yuh-Pyng Sher
2010-12-13

Targeted hepatocellular carcinoma proapoptotic BikDD gene therapy
2009-07-13

Cancer targeted gene therapy of BikDD inhibits orthotopic lung cancer growth and improves long-term survival
2008-12-01

BIK, the founding member of the BH3-only family proteins: mechanisms of cell death and role in cancer and pathogenic processes
2008-11-01

A novel member of the Rhomboid family, RHBDD1, regulates BIK-mediated apoptosis

Ellis Fok
2007-05-21

Ubiquitination of serine, threonine, or lysine residues on the cytoplasmic tail can induce ERAD of MHC-I by viral E3 ligase mK3

Emmanuel J H J Wiertz
2007-05-10

Myeloid cell leukemia-1 inversely correlates with glycogen synthase kinase-3beta activity and associates with poor prognosis in human breast cancer

Xianghuo He, Dung-Fang Lee, Xiaoming Xie, Mien-Chie Hung, Jaw-Ching Liu, Weiya Xia, Jung-Mao Hsu
2007-12-01

Apoptosis induction by Bid requires unconventional ubiquitination and degradation of its N-terminal fragment

Stephen Tait
2007-07-01

Targeted expression of BikDD eradicates pancreatic tumors in noninvasive imaging models

Xiaoming Xie, James Lewis Abbruzzese, Mien-Chie Hung, Weiya Xia, Yongkun Wei, Hsu-Ping Kuo, Bill Spohn
2006-10-01

Regulation of expression of BIK proapoptotic protein in human breast cancer cells: p53-dependent induction of BIK mRNA by fulvestrant and proteasomal degradation of BIK protein
2006-05

Mitochondria primed by death signals determine cellular addiction to antiapoptotic BCL-2 family members

Victoria Del Gaizo Moore, Stanley J. Korsmeyer
2006-03-03

Mutant Bik expression mediated by the enhanced minimal topoisomerase IIalpha promoter selectively suppressed breast tumors in an animal model
2006-04-01

Loss of the tissue-specific proapoptotic BH3-only protein Nbk/Bik is a unifying feature of renal cell carcinoma

Klaus Jung
2005-07-01

Bik/NBK accumulation correlates with apoptosis-induction by bortezomib (PS-341, Velcade) and other proteasome inhibitors
2005-07-01

Ubiquitination on nonlysine residues by a viral E3 ubiquitin ligase

Ken Cadwell
2005-05-01

High-resolution genome-wide mapping of genetic alterations in human glial brain tumors

Branimir Ivan Sikic
2005-03-01

The proteasome inhibitor bortezomib sensitizes cells to killing by death receptor ligand TRAIL via BH3-only proteins Bik and Bim

Jerry Adams
2004-11-01

Cancer-specific activation of the survivin promoter and its potential use in gene therapy

Jin-shing Chen, Mien-Chie Hung, Jaw-Ching Liu, Hsu-Ping Kuo
2003-09

Mutations of the BIK gene in human peripheral B-cell lymphomas
2003-11-01

Enhancement of Bik antitumor effect by Bik mutants

Mien-Chie Hung, Hsu-Ping Kuo
2002-01-01

Systemic tumor suppression by the proapoptotic gene bik

Mien-Chie Hung, Yiyu Zou
2002-03-01

Distinct regions of loss of heterozygosity on 22q in different sites of head and neck squamous cell carcinomas
1999-10

Mapping of a target region of allelic loss to a 0.5-cM interval on chromosome 22q13 in human colorectal cancer

James F. Gusella

Article - wd:Q35440131

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