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PI3K/Akt and apoptosis: size matters

published in: Oncogene

date of publication: 2003-12-01

language: English

main subject: apoptotic process

Cites articles 141

Date

Title

Authors

2003-02-07

Negative regulation of mixed lineage kinase 3 by protein kinase B/AKT leads to cell survival

James R. Woodgett
2003-06-03

JNK-interacting protein 1 promotes Akt1 activation

Moses V Chao, Takehiko Sasaki
2003-02-01

Novel PI analogues selectively block activation of the pro-survival serine/threonine kinase Akt.
2003-06-10

Prostate intraepithelial neoplasia induced by prostate restricted Akt activation: the MPAKT model

Massimo Loda, Philip W. Kantoff, Todd Golub
2003-01-06

Akt activation promotes degradation of tuberin and FOXO3a via the proteasome
2003-04-15

AKT2 inhibition of cisplatin-induced JNK/p38 and Bax activation by phosphorylation of ASK1: implication of AKT2 in chemoresistance.

Domenico Coppola
2003-03-01

Involvement of PI3K/Akt pathway in cell cycle progression, apoptosis, and neoplastic transformation: a target for cancer chemotherapy

William Blalock, Richard A. Franklin, James A. McCubrey
2003-06-06

TRB3: a tribbles homolog that inhibits Akt/PKB activation by insulin in liver

Stephan Herzig
2003-02

PTEN tumor suppressor regulates p53 protein levels and activity through phosphatase-dependent and -independent mechanisms

Robert Cardiff
2003-01-01

Apoptosis-targeted therapies for cancer
2003-05-01

Human mammary epithelial cell transformation through the activation of phosphatidylinositol 3-kinase

Romesh Subramanian, William C Hahn
2002-10-18

Akt forms an intracellular complex with heat shock protein 90 (Hsp90) and Cdc37 and is destabilized by inhibitors of Hsp90 function

Gabriela Chiosis
2002-09-20

Phosphatidylinositol 3-kinase/Akt pathway regulates tuberous sclerosis tumor suppressor complex by phosphorylation of tuberin
2002-02-01

Differential regulation of Akt kinase isoforms by the members of the TCL1 oncogene family
2002-12-06

FOXO proteins regulate tumor necrosis factor-related apoptosis inducing ligand expression. Implications for PTEN mutation in prostate cancer

Jeffrey Milbrandt, B Mark Evers
2002-10-18

Identification and characterization of the interaction between tuberin and 14-3-3zeta

Peter van der Sluijs
2002-05-01

The protein kinase B/Akt signalling pathway in human malignancy
2002-03-28

Akt enhances Mdm2-mediated ubiquitination and degradation of p53.
2002-12-04

14-3-3beta binds to and negatively regulates the tuberous sclerosis complex 2 (TSC2) tumor suppressor gene product, tuberin
2002-09-01

Activity-dependent NMDA receptor-mediated activation of protein kinase B/Akt in cortical neuronal cultures
2002-10-15

Tuberous sclerosis complex-1 and -2 gene products function together to inhibit mammalian target of rapamycin (mTOR)-mediated downstream signaling
2002-12

Crystal structure of an activated Akt/protein kinase B ternary complex with GSK3-peptide and AMP-PNP

Brian Hemmings
2002-03-01

Phosphorylation of HDM2 by Akt.

Karen Vousden
2002-05-01

AKT2 is frequently upregulated in HER-2/neu-positive breast cancers and may contribute to tumor aggressiveness by enhancing cell survival
2002-11-01

Are p27 and p21 cytoplasmic oncoproteins?

Mikhail Blagosklonny
2002-11-01

PKB binding proteins. Getting in on the Akt.

Jongsun Park, Brian Hemmings
2002-08-13

Characterization of PDK2 activity against protein kinase B gamma
2002-08-01

Akt1 regulates a JNK scaffold during excitotoxic apoptosis

Morris J. Birnbaum, Moses V Chao
2002-10-03

Current status of the molecular mechanisms of anticancer drug-induced apoptosis. The contribution of molecular-level analysis to cancer chemotherapy
2002-11-22

Regulation of TSC2 by 14-3-3 binding
2002-05-01

p53 regulates Stat3 phosphorylation and DNA binding activity in human prostate cancer cells expressing constitutively active Stat3.
2002-02-01

Induction of ovarian cancer by defined multiple genetic changes in a mouse model system

Harold E. Varmus, Robert A Soslow

Article - wd:Q35603373

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