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BMP Inhibition in Seminomas Initiates Acquisition of Pluripotency via NODAL Signaling Resulting in Reprogramming to an Embryonal Carcinoma

著者

Manel Esteller

Hubert Schorle

Daniel Nettersheim

Sina Jostes

Humberto J Ferreira

この作品が含まれる作品: PLOS Genetics

出版日: 2015-07-30

main subject: 多能性, embryonal carcinoma

Cites articles 94

Date

タイトル

著者

2015-02-01

SMAD2 and p38 signaling pathways act in concert to determine XY primordial germ cell fate in mice
2014-12-24

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2013-12-26

Analysis of TET expression/activity and 5mC oxidation during normal and malignant germ cell development

Hubert Schorle, Daniel Nettersheim, Lukas C Heukamp
2013-12-01

Wnt and Bmp fit germ cells to a T

Andrea Cantu
2013-11-22

Proteome analysis of the effects of all-trans retinoic acid on human germ cell tumor cell lines

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2013-01-01

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Niels E. Skakkebæk, Ewa Rajpert-De Meyts, Kristian Almstrup
2013-01-01

Nodal/Cripto signaling in fetal male germ cell development: implications for testicular germ cell tumors

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2013-06-14

Id proteins are critical downstream effectors of BMP signaling in human pulmonary arterial smooth muscle cells

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2013-03-08

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A mesodermal factor, T, specifies mouse germ cell fate by directly activating germline determinants

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Serum regulation of Id1 expression by a BMP pathway and BMP responsive element
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Highly coordinated proteome dynamics during reprogramming of somatic cells to pluripotency

Wolfgang Huber, Konrad Hochedlinger, Julian Gehring, Jenny Hansson, Jose M Polo, Jeroen Krijgsveld
2012-11-01

Endogenous Nodal signaling regulates germ cell potency during mammalian testis development

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2012-07-01

SOX17 methylation inhibits its antagonism of Wnt signaling pathway in lung cancer
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Complete pipeline for Infinium(®) Human Methylation 450K BeadChip data processing using subset quantile normalization for accurate DNA methylation estimation

Jorg Tost
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Establishment of a versatile seminoma model indicates cellular plasticity of germ cell tumor cells

Hubert Schorle, Daniel Nettersheim, Stefan Schlatt, Oliver Brüstle
2012-09-01

Antagonism of Nodal signaling by BMP/Smad5 prevents ectopic primitive streak formation in the mouse amnion

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Nodal signaling regulates the entry into meiosis in fetal germ cells

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2011-01-01

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Mutation in the type IB bone morphogenetic protein receptor Alk6b impairs germ-cell differentiation and causes germ-cell tumors in zebrafish

Leendert Looijenga
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Bone morphogenetic protein signalling activity distinguishes histological subsets of paediatric germ cell tumours
2011-06-08

TGF-β1, EGF and FGF4 synergistically induce differentiation of the seminoma cell line TCam-2 into a cell type resembling mixed non-seminoma

Hubert Schorle, Daniel Nettersheim, Leendert Looijenga
2011-06-02

Expression and interdependencies of pluripotency factors LIN28, OCT3/4, NANOG and SOX2 in human testicular germ cells and tumours of the testis

Leendert Looijenga
2011-05-12

Dissecting the molecular pathways of (testicular) germ cell tumour pathogenesis; from initiation to treatment-resistance
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Role of BMP, FGF, calcium signaling, and Zic proteins in vertebrate neuroectodermal differentiation
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NANOG promoter methylation and expression correlation during normal and malignant human germ cell development

Hubert Schorle
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Functional genomics reveals a BMP-driven mesenchymal-to-epithelial transition in the initiation of somatic cell reprogramming

Laurent David, Knut Woltjen, Alessandro Datti, Andras Nagy, Jeffrey L. Wrana
2010-08-01

Global DNA methylation in fetal human germ cells and germ cell tumours: association with differentiation and cisplatin resistance

Ole Ammerpohl, Carsten Bokemeyer
2010-04-22

BMP signaling controls formation of a primordial germ cell niche within the early genital ridges

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