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KIT with D816 mutations cooperates with CBFB-MYH11 for leukemogenesis in mice

published in: Blood

date of publication: 2011-12-07

language: English

Cites articles 50

Date

Title

Authors

2011-01-24

C-KIT mutation cooperates with full-length AML1-ETO to induce acute myeloid leukemia in mice

Yue-Ying Wang
2010-05-01

FLT3 and KIT mutated pediatric acute myeloid leukemia (AML) samples are sensitive in vitro to the tyrosine kinase inhibitor SU11657.
2009-12-22

Elimination of human lung cancer stem cells through targeting of the stem cell factor-c-kit autocrine signaling loop
2009-12

Oncogenic signaling from the hematopoietic growth factor receptors c-Kit and Flt3
2009-09-01

Monitoring of minimal residual disease in patients with core binding factor acute myeloid leukemia and the impact of C-KIT, FLT3, and JAK2 mutations on clinical outcome.
2009-05-21

AML1-ETO9a is correlated with C-KIT overexpression/mutations and indicates poor disease outcome in t(8;21) acute myeloid leukemia-M2.
2008-04-01

Unique effects of KIT D816V in BaF3 cells: induction of cluster formation, histamine synthesis, and early mast cell differentiation antigens

Gregor Hoermann, Martin Bilban, Richard Moriggl, Roland Liblau, Peter Valent
2008-04-01

Regulation of hematopoietic stem cells by the steel factor/KIT signaling pathway

David Kent, Connie Eaves
2008-11-17

The c-Kit/D816V mutation eliminates the differences in signal transduction and biological responses between two isoforms of c-Kit

Lars Rönnstrand
2008-07-07

Complementing mutations in core binding factor leukemias: from mouse models to clinical applications
2008-10-01

Multiple sporadic gastrointestinal stromal tumors (GISTs) of the proximal stomach are caused by different somatic KIT mutations suggesting a field effect

Luigi Tornillo
2007-10-29

FLT3-ITD cooperates with inv(16) to promote progression to acute myeloid leukemia

Vishnu V B Reddy
2007-10-25

Cooperating mutations of receptor tyrosine kinases and Ras genes in childhood core-binding factor acute myeloid leukemia and a comparative analysis on paired diagnosis and relapse samples
2007

c-Kit--a hematopoietic cell essential receptor tyrosine kinase
2007-01-01

Expression of c-kit proto-oncogene product in breast cancer tissues
2006-12-21

CBFB-MYH11 hinders early T-cell development and induces massive cell death in the thymus
2006-08-01

Adverse prognostic significance of KIT mutations in adult acute myeloid leukemia with inv(16) and t(8;21): a Cancer and Leukemia Group B Study

Cancer and Leukemia Group B, Guido Marcucci, Clara D. Bloomfield, Krzysztof Mrózek, James W Vardiman, Richard A. Larson, Jonathan E Kolitz, Peter Paschka, Amy S Ruppert, Tamara Vukosavljevic, Danilo Perrotti
2006-05-01

Prognostic impact of c-KIT mutations in core binding factor leukemias: an Italian retrospective study

Carla B. Ripamonti, Alessandro Beghini
2006-10-23

Neoplasia driven by mutant c-KIT is mediated by intracellular, not plasma membrane, receptor signaling

Zhifu Xiang, Michael H Tomasson
2006-06-01

Incidence and prognostic impact of c-Kit, FLT3, and Ras gene mutations in core binding factor acute myeloid leukemia (CBF-AML)

Olivier Hermine, Bruno Quesnel, Claude Preudhomme
2006-01-01

Cbf beta-SMMHC induces distinct abnormal myeloid progenitors able to develop acute myeloid leukemia

Michelle M Le Beau
2006-06-01

Bax, bcl-2 and c-kit expression in non-small-cell lung cancer and their effects on prognosis
2005-10-27

KIT-D816 mutations in AML1-ETO-positive AML are associated with impaired event-free and overall survival

Claudia Schoch, Torsten Haferlach, Susanne Schnittger
2005-09-27

PKC412 inhibits in vitro growth of neoplastic human mast cells expressing the D816V-mutated variant of KIT: comparison with AMN107, imatinib, and cladribine (2CdA) and evaluation of cooperative drug effects
2005-06-21

Activity of the tyrosine kinase inhibitor PKC412 in a patient with mast cell leukemia with the D816V KIT mutation

Ching-Cheng Chen, Tracy I George, Michael C. Heinrich, Stephen J. Galli, Len Neckers
2005-03-24

Activation mutations of human c-KIT resistant to imatinib mesylate are sensitive to the tyrosine kinase inhibitor PKC412.
2005-01-12

Imatinib mesylate in the treatment of Core Binding Factor leukemias with KIT mutations. A report of three cases

Alessandro Beghini
2004-12-23

KIT exon 8 mutations associated with core-binding factor (CBF)-acute myeloid leukemia (AML) cause hyperactivation of the receptor in response to stem cell factor.

Susanne Schnittger
2004-03-24

Identification of genes that synergize with Cbfb-MYH11 in the pathogenesis of acute myeloid leukemia
2004-08-01

KIT activating mutations: incidence in adult and pediatric acute myeloid leukemia, and identification of an internal tandem duplication
2004-01-01

Second hit mutations in the RTK/RAS signaling pathway in acute myeloid leukemia with inv(16)

Anne C Goodeve
2003-07-24

An activated receptor tyrosine kinase, TEL/PDGFbetaR, cooperates with AML1/ETO to induce acute myeloid leukemia in mice

Article - wd:Q35776437

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