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Iron-deficiency anemia from matriptase-2 inactivation is dependent on the presence of functional Bmp6

author

Carlos López Otín

1958 -

Jean-Christophe Deschemin

Léon Kautz

1982 -

Gael Nicolas

1979 -

published in: Blood

date of publication: 2010-10-12

language: English

Cites articles 20

Date

Title

Authors

2010-03-03

Down-regulation of Bmp/Smad signaling by Tmprss6 is required for maintenance of systemic iron homeostasis

Nancy Andrews, Mark D Fleming
2010-02-02

Oncostatin M is a potent inducer of hepcidin, the iron regulatory hormone

Jean-Christophe Deschemin
2009-11-01

Suppression of the hepcidin-encoding gene Hamp permits iron overload in mice lacking both hemojuvelin and matriptase-2/TMPRSS6

Bruce Beutler
2009-06-23

Hepcidin, the iron watcher
2009-04-18

Matriptase-2 (TMPRSS6): a proteolytic regulator of iron homeostasis

Carlos López Otín, Alicia R Folgueras, Gloria Velasco, John D Hooper
2009-04-01

Lack of the bone morphogenetic protein BMP6 induces massive iron overload

Léon Kautz, François Canonne-Hergaux
2009-10-01

Iron-refractory iron deficiency anemia
2009-03-01

BMP6 is a key endogenous regulator of hepcidin expression and iron metabolism

Elena Corradini, Antonello Pietrangelo, Yin Xia
2008-12-01

The serine protease matriptase-2 (TMPRSS6) inhibits hepcidin activation by cleaving membrane hemojuvelin

Clara Camaschella, Laura Silvestri
2008-06-06

Iron regulates phosphorylation of Smad1/5/8 and gene expression of Bmp6, Smad7, Id1, and Atoh8 in the mouse liver

Léon Kautz
2008-05-23

The serine protease TMPRSS6 is required to sense iron deficiency

Bruce Beutler, Suzanne Mudd
2008-05

Mutations in TMPRSS6 cause iron-refractory iron deficiency anemia (IRIDA)

Kyriacos Markianos, Matthew M. Heeney, Nancy Andrews, Mark D Fleming
2008-01-01

Regulation of iron acquisition and storage: consequences for iron-linked disorders
2008-06-03

Membrane-bound serine protease matriptase-2 (Tmprss6) is an essential regulator of iron homeostasis.

Carlos López Otín, Alicia R Folgueras, Gloria Velasco, Rubén Cabanillas, Cecilia Garabaya, Aurora Astudillo-González
2008-10-01

New and old players in the hepcidin pathway

Laura Silvestri
2007-01-01

Iron homeostasis

Nancy Andrews
2006-04-09

Bone morphogenetic protein signaling by hemojuvelin regulates hepcidin expression

Yin Xia, Nancy Andrews, Raymond T Chung
2005-12-08

Chronic hepcidin induction causes hyposideremia and alters the pattern of cellular iron accumulation in hemochromatotic mice.

Nancy Andrews, Gael Nicolas, François Canonne-Hergaux
2005-12-01

A role of SMAD4 in iron metabolism through the positive regulation of hepcidin expression
2005-08-01

A mouse model of juvenile hemochromatosis

Nancy Andrews, Mark D Fleming, Geraldine Pinkus

Article - wd:Q35825937

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