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Synaptic NMDA receptors mediate hypoxic excitotoxic death

著者

Steven Mennerick

この作品が含まれる作品: ジャーナル・オブ・ニューロサイエンス

出版日: 2012-05-01

言語: 英語

main subject: 低酸素症, 興奮毒性

Cites articles 66

Date

タイトル

著者

2012-01-11

Tonic NMDA receptor-mediated current in prefrontal cortical pyramidal cells and fast-spiking interneurons
2011-09-01

Synaptic and extrasynaptic NMDA receptors differentially modulate neuronal cyclooxygenase-2 function, lipid peroxidation, and neuroprotection
2011-05-14

Presynaptic silencing is an endogenous neuroprotectant during excitotoxic insults
2011-05-07

Mechanisms underlying NMDA receptor synaptic/extrasynaptic distribution and function

Lynn A Raymond
2011-03-01

A signaling cascade of nuclear calcium-CREB-ATF3 activated by synaptic NMDA receptors defines a gene repression module that protects against extrasynaptic NMDA receptor-induced neuronal cell death and ischemic brain damage

Roland Veltkamp
2010-09-15

Synaptic versus extrasynaptic NMDA receptor signalling: implications for neurodegenerative disorders

ジャイルズ・E・ハーディンガム
2010-08-18

Memantine preferentially blocks extrasynaptic over synaptic NMDA receptor currents in hippocampal autapses
2010-04-19

Synaptic activity and nuclear calcium signaling protect hippocampal neurons from death signal-associated nuclear translocation of FoxO3a induced by extrasynaptic N-methyl-D-aspartate receptors
2010-02-01

Diverse voltage-sensitive dyes modulate GABAA receptor function

Charles F Zorumski
2010-11-01

Activation of extrasynaptic, but not synaptic, NMDA receptors modifies amyloid precursor protein expression pattern and increases amyloid-ß production

Olivier Nicole, Alain Buisson
2010-03-08

Simulated ischaemia induces Ca2+-independent glutamatergic vesicle release through actin filament depolymerization in area CA1 of the hippocampus
2009-11-15

Balance between synaptic versus extrasynaptic NMDA receptor activity influences inclusions and neurotoxicity of mutant huntingtin

Michael R. Hayden, Marcus Kaul, Stuart A. Lipton
2009-08-17

Memantine binding to a superficial site on NMDA receptors contributes to partial trapping
2009-05-29

Coupling diverse routes of calcium entry to mitochondrial dysfunction and glutamate excitotoxicity

Christine A. Brantner
2009-03-01

Mg2+ imparts NMDA receptor subtype selectivity to the Alzheimer's drug memantine
2009-04-01

Reverse glial glutamate uptake triggers neuronal cell death through extrasynaptic NMDA receptor activation

Olivier Nicole, Alain Buisson
2008-04-01

Beyond NMDA and AMPA glutamate receptors: emerging mechanisms for ionic imbalance and cell death in stroke
2008-03-23

Synaptic NMDA receptor activity boosts intrinsic antioxidant defenses

Francesc X Soriano, ジャイルズ・E・ハーディンガム, Peter Ghazal, David J Wyllie, Karen Horsburgh, Angela Kaindl, Marco Sifringer
2008-08-18

Neuronal viability is controlled by a functional relation between synaptic and extrasynaptic NMDA receptors

Olivier Nicole, Alain Buisson
2007-10-01

Pathologically activated therapeutics for neuroprotection
2007-08-23

Extrasynaptic and synaptic NMDA receptors form stable and uniform pools in rat hippocampal slices.
2007-03-01

NMDA receptor subunits have differential roles in mediating excitotoxic neuronal death both in vitro and in vivo.

Yu Tian Wang, Tak Pan Wong, Michelle Aarts, Ted Weita Lai, Dong Chuan Wu
2006-11-21

NMDA receptor surface mobility depends on NR2A-2B subunits

Daniel Choquet, Laurent Cognet, Laurent Groc
2006-05

Neuroprotective properties of memantine in differentin vitroandin vivomodels of excitotoxicity

Klas Blomgren, Marcel Leist
2006-04-01

Preconditioning doses of NMDA promote neuroprotection by enhancing neuronal excitability

ニール・R・ハーディンガム, Francesc X Soriano, ジャイルズ・E・ハーディンガム
2006-08-01

Actin-dependent activation of presynaptic silent synapses contributes to long-term synaptic plasticity in developing hippocampal neurons

Jun Yao
2006-05-01

Opposing role of synaptic and extrasynaptic NMDA receptors in regulation of the extracellular signal-regulated kinases (ERK) activity in cultured rat hippocampal neurons.

Igor Medina, Yuriy Salyha, Christophe Pellegrino, Anton I Ivanov, Yehezkel Ben-Ari
2005-12-20

Mechanism of action of memantine
2004-04-01

Characterization of novel L-threo-beta-benzyloxyaspartate derivatives, potent blockers of the glutamate transporters
2002-11-01

NMDA receptor 2 (NR2) C-terminal control of NR open probability regulates synaptic transmission and plasticity at a cerebellar synapse

Frank Steigerwald, Egidio D'Angelo, Ole Petter Ottersen
2002-05

Extrasynaptic NMDARs oppose synaptic NMDARs by triggering CREB shut-off and cell death pathways
2002-11-01

Coupling of extrasynaptic NMDA receptors to a CREB shut-off pathway is developmentally regulated

ジャイルズ・E・ハーディンガム

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