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Critical role of soluble amyloid-β for early hippocampal hyperactivity in a mouse model of Alzheimer's disease

autor

Bert Sakmann

1942 -

Marc Aurel Busche

Arthur Konnerth

1953 -

Matthias Staufenbiel

opublikowano w: Proceedings of the National Academy of Sciences

data publikacji: 2012-05-16

język: język angielski

główny temat: choroba Alzheimera

Cites articles 47

Data

Tytuł

Autorzy

2010-10-01

Amyloid beta-protein dimers rapidly form stable synaptotoxic protofibrils

John Collinge
2010-10-03

Functional imaging of hippocampal place cells at cellular resolution during virtual navigation

Daniel A Dombeck, Christopher D. Harvey, Lin Tian, Loren L Looger, David W. Tank
2010-09-01

NMDA-mediated Ca(2+) influx drives aberrant ryanodine receptor activation in dendrites of young Alzheimer's disease mice
2010-05-12

Longitudinal fMRI in elderly reveals loss of hippocampal activation with clinical decline
2010-03-19

How do Soluble Oligomers of Amyloid beta-protein Impair Hippocampal Synaptic Plasticity?

Dennis J. Selkoe
2010-04-19

The presence of sodium dodecyl sulphate-stable Abeta dimers is strongly associated with Alzheimer-type dementia

George M. Savva, Carol Brayne, Paul Ince, Dennis J. Selkoe, Gill Forster, Medical Research Council Cognitive Function and Ageing Study
2010-01-19

Synthetic amyloid-beta oligomers impair long-term memory independently of cellular prion protein

Marten Beeg, Matteo Stravalaci, Emiliano Biasini, Claudia Manzoni, Tiziana Borsello, Roberto Chiesa, Marco Gobbi, Mario Salmona, Alessandra Sclip, Claudia Balducci
2010-04-01

A mouse model of amyloid beta oligomers: their contribution to synaptic alteration, abnormal tau phosphorylation, glial activation, and neuronal loss in vivo

Kazuhiro Ito, William L. Klein
2010-01-12

Amyloid beta oligomers induce Ca2+ dysregulation and neuronal death through activation of ionotropic glutamate receptors

Ramon Trullas, Carlos Matute, Elena Alberdi, Maria Victoria Sánchez-Gómez, Alberto Luis Perez Samartin, María Domercq
2010-09-21

Initiation and propagation of neurodegeneration
2009-08-14

Sparsification of neuronal activity in the visual cortex at eye-opening

Olga Garaschuk, Arthur Konnerth, Nathalie L Rochefort
2009-06-01

Soluble oligomers of amyloid Beta protein facilitate hippocampal long-term depression by disrupting neuronal glutamate uptake

Soyon Hong, Dennis J. Selkoe
2008-10-19

Phospholipase A2 reduction ameliorates cognitive deficits in a mouse model of Alzheimer's disease

John W Newman, Lennart Mucke, Joseph V Bonventre
2008-08-04

Soluble amyloid-beta peptides potently disrupt hippocampal synaptic plasticity in the absence of cerebrovascular dysfunction in vivo

NengWei Hu, Michael J Rowan
2008-07-31

Neuronal calcium mishandling and the pathogenesis of Alzheimer's disease
2008-08

Amyloid-beta protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory

Michael J Rowan, Dennis J. Selkoe, Bernardo L. Sabatini
2008-09-01

Clusters of hyperactive neurons near amyloid plaques in a mouse model of Alzheimer's disease.

Christian Haass, Arthur Konnerth, Olga Garaschuk, Marc Aurel Busche, Matthias Staufenbiel
2008-08-07

Dynamics of Abeta turnover and deposition in different beta-amyloid precursor protein transgenic mouse models following gamma-secretase inhibition.

Matthias Staufenbiel
2008-07-01

Abeta plaques lead to aberrant regulation of calcium homeostasis in vivo resulting in structural and functional disruption of neuronal networks

Bradley Hyman
2007-09-01

Aberrant excitatory neuronal activity and compensatory remodeling of inhibitory hippocampal circuits in mouse models of Alzheimer's disease

Erik D. Roberson, Jun Wang, Jeffrey L. Noebels, Jorge J Palop, Jeannie Chin, Lennart Mucke
2007-06-04

Accelerating amyloid-beta fibrillization reduces oligomer levels and functional deficits in Alzheimer disease mouse models

Sylvain Lesné, Karen Ashe, Lennart Mucke
2007-12-23

Targeted patch-clamp recordings and single-cell electroporation of unlabeled neurons in vivo

Kazuo Kitamura, Benjamin Judkewitz, Winfried Denk
2006-03-16

A specific amyloid-beta protein assembly in the brain impairs memory

Sylvain Lesné, Karen Ashe
2006-01-01

Targeted bulk-loading of fluorescent indicators for two-photon brain imaging in vivo.

Olga Garaschuk, Arthur Konnerth
2005-11-01

Functional activation imaging in aging and dementia
2005-09-12

Imaging input and output of neocortical networks in vivo

Fritjof Helmchen
2005-08-01

Increased hippocampal activation in mild cognitive impairment compared to normal aging and AD

Marilyn S. Albert
2005-08-01

Regulation of NMDA receptor trafficking by amyloid-beta

Eun Young Choi, Cláudia Guimas Almeida, Gunnar K. Gouras, Paul Greengard, Angus C. Nairn
2005-01

Natural oligomers of the amyloid-beta protein specifically disrupt cognitive function

Karen Ashe
2005-09-01

Acute gamma-secretase inhibition improves contextual fear conditioning in the Tg2576 mouse model of Alzheimer's disease
2004-09-29

Sulforhodamine 101 as a specific marker of astroglia in the neocortex in vivo

Fritjof Helmchen
2004-08-05

Pathways towards and away from Alzheimer's disease

Artykuł - wd:Q36001449

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