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4β-hydroxycholesterol as an endogenous CYP3A marker in cancer patients treated with taxanes

author

Alex Sparreboom

Bronno van der Holt

Jaap Verweij

published in: British Journal of Clinical Pharmacology

date of publication: 2015-06-28

language: English

Cites articles 41

Date

Title

Authors

2015-05-07

Inter-patient variability in docetaxel pharmacokinetics: A review

Alex Sparreboom
2012-06-18

Influence of polymorphic OATP1B-type carriers on the disposition of docetaxel

Alex Sparreboom, Sharyn D. Baker, Ron Mathijssen, Anne-Joy M de Graan, Cynthia L Lancaster, Alice A Gibson, Ron van Schaik
2012-05-29

Influence of smoking on the pharmacokinetics and toxicity profiles of taxane therapy

Sharyn D. Baker, Erik Wiemer, Bronno van der Holt, Jaap Verweij
2011-11-01

Guide to Receptors and Channels (GRAC), 5th edition

Alistair Mathie
2011-02-25

Docetaxel metabolism is not altered by imatinib: findings from an early phase study in metastatic breast cancer

Vered Stearns
2011-02-01

4β-Hydroxycholesterol, an endogenous marker of CYP3A4/5 activity in humans

Ulf Diczfalusy, Leif Bertilsson
2011-05-28

Docetaxel pharmacokinetics and its correlation with two in vivo probes for cytochrome P450 enzymes: the C14-erythromycin breath test and the antipyrine clearance test

Prudence Francis, Carleen Cullinane
2010-03-02

Does the long plasma half-life of 4beta-hydroxycholesterol impact its utility as a cytochrome P450 3A (CYP3A) metric?
2009-05-20

Plasma 4beta-hydroxycholesterol: an endogenous CYP3A metric?
2008-11-06

4beta-hydroxycholesterol as an endogenous marker for CYP3A4/5 activity. Stability and half-life of elimination after induction with rifampicin

Ulf Diczfalusy, Leif Bertilsson
2008-03-01

4Beta-hydroxycholesterol is a new endogenous CYP3A marker: relationship to CYP3A5 genotype, quinine 3-hydroxylation and sex in Koreans, Swedes and Tanzanians

Ulf Diczfalusy, Eleni Aklillu, Lars L. Gustafsson, Leif Bertilsson, Hyung-Keun Roh, Jane G Sayi, Rajaa A Mirghani, Annika Allqvist, Mary Jande
2006-07-22

Influence of high-dose ketoconazole on the pharmacokinetics of docetaxel

Jaap Verweij
2006-09-01

CYP3A5 genotype has significant effect on quinine 3-hydroxylation in Tanzanians, who have lower total CYP3A activity than a Swedish population

Eleni Aklillu, Jaran Eriksen, Lars L. Gustafsson, Leif Bertilsson, Agneta Wennerholm, Jane G Sayi, Rajaa A Mirghani, Annika Allqvist, Mary Jande
2006-04-01

Quantitative effect of gender, age, liver function, and body size on the population pharmacokinetics of Paclitaxel in patients with solid tumors

Jos Beijnen, Alwin D R Huitema, Jan H M Schellens
2006-12-01

Synthesis of pyridine-carboxylate derivatives of hydroxysteroids for liquid chromatography-electrospray ionization-mass spectrometry
2005-12-01

Genotyping and phenotyping cytochrome P450: perspectives for cancer treatment
2005-06-01

CYP3A probes can quantitatively predict the in vivo kinetics of other CYP3A substrates and can accurately assess CYP3A induction and inhibition

Evan D Kharasch
2005-04-01

There are no useful CYP3A probes that quantitatively predict the in vivo kinetics of other CYP3A substrates and no expectation that one will be found
2005-01-18

Randomized pharmacokinetic and pharmacodynamic study of docetaxel: dosing based on body-surface area compared with individualized dosing based on cytochrome P450 activity estimated using a urinary metabolite of exogenous cortisol
2004-11-01

Prediction of irinotecan pharmacokinetics by use of cytochrome P450 3A4 phenotyping probes

Alex Sparreboom, Jaap Verweij, Trinet Rietveld
2004-01-01

Simultaneous analysis of docetaxel and the formulation vehicle polysorbate 80 in human plasma by liquid chromatography/tandem mass spectrometry

Alex Sparreboom, Jaap Verweij
2003-05-01

Population pharmacokinetic modelling of unbound and total plasma concentrations of paclitaxel in cancer patients

Rolf Larsson, Peter Nygren, Jonas Bergh
2002-10-15

Managing taxane toxicities
2002-06-20

Metabolism of 4 beta -hydroxycholesterol in humans

Maria Norlin, Ingemar Björkhem, Ewa C Ellis, Irina Pikuleva, Ulf Diczfalusy, Gösta Eggertsen
2001-08-20

Antiepileptic drugs increase plasma levels of 4beta-hydroxycholesterol in humans: evidence for involvement of cytochrome p450 3A4

Lionel Bretillon, Ulf Diczfalusy
2001-05-01

Population pharmacokinetics and pharmacokinetic-pharmacodynamic relationships for docetaxel
2000-06-01

Combining taxanes with radiation for solid tumors
2000-04-01

Phenotyping of drug-metabolizing enzymes in adults: a review of in-vivo cytochrome P450 phenotyping probes
2000-04-01

The effect of an individual's cytochrome CYP3A4 activity on docetaxel clearance
2000-06-01

Correlation between docetaxel clearance and estimated cytochrome P450 activity by urinary metabolite of exogenous cortisol
1999-04-01

Cremophor EL-mediated alteration of paclitaxel distribution in human blood: clinical pharmacokinetic implications
1998-01-01

Determination of paclitaxel in human plasma using single solvent extraction prior to isocratic reversed-phase high-performance liquid chromatography with ultraviolet detection

Article - wd:Q36072512

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