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Drug resistance in epilepsy: putative neurobiologic and clinical mechanisms

published in: Epilepsia

date of publication: 2005-06-01

language: English

Cites articles 96

Date

Title

Authors

2005-02-01

Potential role of drug transporters in the pathogenesis of medically intractable epilepsy

Patrick Kwan, Martin J Brodie
2005-01-01

Blood-brain barrier active efflux transporters: ATP-binding cassette gene family
2004-04-01

Efficacy and tolerability of the new antiepileptic drugs II: treatment of refractory epilepsy: report of the Therapeutics and Technology Assessment Subcommittee and Quality Standards Subcommittee of the American Academy of Neurology and the American Epilepsy Society

Jacqueline French, Therapeutics and Technology Assessment Subcommittee of the American Academy of Neurology, John M Stern
2004-07-01

New horizons in the development of antiepileptic drugs: the search for new targets.
2004-07

The neurobiology of antiepileptic drugs

Wolfgang Löscher
2004-06-21

The synaptic vesicle protein SV2A is the binding site for the antiepileptic drug levetiracetam
2004-06-01

Genes and mutations in human idiopathic epilepsy
2004-01-01

Analysis of GABAA receptor function and dissection of the pharmacology of benzodiazepines and general anesthetics through mouse genetics
2004-01-01

ABC transporters and the blood-brain barrier
2004-05-01

Expression and cellular distribution of multidrug resistance-related proteins in the hippocampus of patients with mesial temporal lobe epilepsy

Eleonora Aronica
2004-01-01

Neuronal expression of the drug efflux transporter P-glycoprotein in the rat hippocampus after limbic seizures

Heidrun Potschka, Holger A Volk
2004-01-01

Increased expression of the multidrug transporter P-glycoprotein in limbic brain regions after amygdala-kindled seizures in rats

Heidrun Potschka
2004-07-01

Pharmacoresistance and expression of multidrug transporter P-glycoprotein in kindled rats

Heidrun Potschka
2004-10-09

Significance of MDR1 and multiple drug resistance in refractory human epileptic brain

Nicola Marchi, Damir Janigro
2004-01-01

Valproic acid uptake by bovine brain microvessel endothelial cells: role of active efflux transport

Moji Christianah Adeyeye
2004-02-01

Inhibition of multidrug transporters by verapamil or probenecid does not alter blood-brain barrier penetration of levetiracetam in rats

Heidrun Potschka
2004-06-24

Plasma membrane localization of multidrug resistance-associated protein homologs in brain capillary endothelial cells
2004-04-01

Clinical aspects of the MDR1 (ABCB1) gene polymorphism
2004-07-01

Pharmacogenomics of drug transporters: a new approach to functional analysis of the genetic polymorphisms of ABCB1 (P-glycoprotein/MDR1).

Toshihisa Ishikawa
2004-08-24

Use of verapamil as a potential P-glycoprotein inhibitor in a patient with refractory epilepsy
2004-01-01

Emergent properties of CNS neuronal networks as targets for pharmacology: application to anticonvulsant drug action
2004-01-01

PET Studies on P-glycoprotein function in the blood-brain barrier: how it affects uptake and binding of drugs within the CNS

Joost Bart
2004-10-01

What is the evidence that oxcarbazepine and carbamazepine are distinctly different antiepileptic drugs?
2003-01-01

Pharmacoresistance: modern concept and basic data derived from human brain tissue
2003-01-01

How long does it take for partial epilepsy to become intractable?
2003-04-01

Do epileptic seizures damage the brain?

Asla Pitkänen
2003-03-01

Hippocampal sclerosis is a progressive disorder: a longitudinal volumetric MRI study.

Aashit Shah
2003-03-01

Progressive neocortical damage in epilepsy.

Alexander Hammers, Ley Sander, John S. Duncan
2003-05-01

Dose-response trial of pregabalin adjunctive therapy in patients with partial seizures

Jacqueline French
2003-04-01

A novel mechanism underlying drug resistance in chronic epilepsy

Uwe Heinemann
2003-06-01

Anticonvulsant pharmacology of voltage-gated Na+ channels in hippocampal neurons of control and chronically epileptic rats
2003-01-01

Molecular and functional changes in voltage-dependent Na(+) channels following pilocarpine-induced status epilepticus in rat dentate granule cells

Article - wd:Q36157234

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