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Lipidomic and metabolomic characterization of a genetically modified mouse model of the early stages of human type 1 diabetes pathogenesis

auteur·ice

Anne Julie Overgaard

David De Souza

Dedreia L Tull

Peter J Meikle

Flemming Pociot

2000 -

publié dans: Metabolomics

date de publication: 2015-11-17

sujet principal: pathogenèse, diabète de type 1

Articles cités 35

Date

Titre

Auteur·ices

2015-05-01

Lysophospholipid receptors in drug discovery
2014-11-21

Comparative gene identification-58 (CGI-58) promotes autophagy as a putative lysophosphatidylglycerol acyltransferase
2013-12-24

Impact of insulin deprivation and treatment on sphingolipid distribution in different muscle subcellular compartments of streptozotocin-diabetic C57Bl/6 mice

Agnieszka Blachnio-Zabielska, Piotr Zabielski
2013-12-07

Metabolomics in diabetes
2013-09-30

Lysophosphatidylcholine triggers TLR2- and TLR4-mediated signaling pathways but counteracts LPS-induced NO synthesis in peritoneal macrophages by inhibiting NF-κB translocation and MAPK/ERK phosphorylation

Igor C Almeida, Patricia Bozza, Carla D Lopes
2013-09-27

Plasma lipid profiling shows similar associations with prediabetes and type 2 diabetes

Laura Almasy, Christopher K Barlow, Paul Zimmet, John Blangero, Joanne E. Curran, Jeremy B M Jowett, Michael C. Mahaney, Peter J Meikle, Anthony G Comuzzie, Gerard C L Wong, Jacquelyn M Weir, Melissa A Greeve
2013-07-18

Plasma lipid profiling in a large population-based cohort

Laura Almasy, John Blangero, Joanne E. Curran, Jeremy B M Jowett, Michael C. Mahaney, Christopher K Barlow, Peter J Meikle, Anthony G Comuzzie, Gerard C L Wong, Jacquelyn M Weir, Melissa A Greeve
2013-04

Economic costs of diabetes in the U.S. in 2012
2012-12-01

Role of recombination activating genes in the generation of antigen receptor diversity and beyond
2012-05-01

Roles of ceramide and sphingolipids in pancreatic β-cell function and dysfunction

Peter J Meikle, Trevor Biden
2012-05-30

PyMS: a Python toolkit for processing of gas chromatography-mass spectrometry (GC-MS) data. Application and comparative study of selected tools

Sean O'Callaghan, Moshe Olshansky, David De Souza, Ute Roessner, Tony Bacic
2012-07-01

Estimating the current and future costs of Type 1 and Type 2 diabetes in the UK, including direct health costs and indirect societal and productivity costs

Danielle Varley
2012-01-20

Lysophosphatidylinositol signalling: new wine from an old bottle

Roberto Piñeiro, Marco Falasca
2011-10-27

Metabolic regulation in progression to autoimmune diabetes

Tuulikki Seppänen-Laakso, Taina Härkönen, Peddinti V. Gopalacharyulu, Maria Saarela, Samuel Kaski, Eriika Savontaus, Erno Lindfors, Mikael Knip
2011-11-01

Age- and islet autoimmunity-associated differences in amino acid and lipid metabolites in children at risk for type 1 diabetes

Matej Orešič, Tuulikki Seppänen-Laakso, Ezio Bonifacio, Tuulia Hyötyläinen
2011-03-25

The potential usefulness of taurine on diabetes mellitus and its complications

Junichi Azuma, Stephen W. Schaffer
2009-04-15

Role of cardiolipin peroxidation and Ca2+ in mitochondrial dysfunction and disease
2008-12-15

Dysregulation of lipid and amino acid metabolism precedes islet autoimmunity in children who later progress to type 1 diabetes

Tuulikki Seppänen-Laakso, Heikki Hyöty, Kirsti Näntö-Salonen, Riitta Veijola, Matej Orešič, Jorma Ilonen, Mikael Knip, Riitta Lahesmaa
2008-03-03

The intrauterine metabolic environment modulates the gene expression pattern in fetal rat islets: prevention by maternal taurine supplementation
2007-06-01

CD40 is required for development of islet inflammation in the RIP-CD154 transgenic mouse model of type 1 diabetes.
2006-03-11

Type 1 diabetes
2004-10-01

Local activation of dendritic cells leads to insulitis and development of insulin-dependent diabetes in transgenic mice expressing CD154 on the pancreatic beta-cells
2004-09-01

Cholesterol metabolism in type 1 diabetes
2002-07-01

Lysophosphatidylcholine as a ligand for immunoregulation
2001-01-01

CD40 ligation ablates the tolerogenic potential of lymphoid dendritic cells
2000-01-01

Characterization of plasma unsaturated lysophosphatidylcholines in human and rat
1998-06-01

T-cell help for cytotoxic T lymphocytes is mediated by CD40-CD40L interactions.

Rene E Toes
1998-06-01

Help for cytotoxic-T-cell responses is mediated by CD40 signalling.

William R Heath
1998-06-01

A conditioned dendritic cell can be a temporal bridge between a CD4+ T-helper and a T-killer cell.

Francesca Di Rosa
1996-07-01

Mannose, mannitol, fructose and 1,5-anhydroglucitol concentrations measured by gas chromatography/mass spectrometry in blood plasma of diabetic patients
1995-05-01

Plasma and platelet taurine are reduced in subjects with insulin-dependent diabetes mellitus: effects of taurine supplementation
1994-09-01

On the pathogenesis of IDDM

Henrik U Andersen, Flemming Pociot

Article - wd:Q36289958

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