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Modulation of TRP Channel Activity by Hydroxylation and Its Therapeutic Potential.

auteur

Grigori Y Rychkov

Daniel J Peet

gepubliceerd in: Pharmaceuticals

publicatiedatum: 2017-03-27

Cites articles 52

Date

Titel

Auteurs

2016-12-01

A Sensor for Low Environmental Oxygen in the Mouse Main Olfactory Epithelium

David Macias, Randall S. Johnson, Trese Leinders-Zufall, Frank Zufall, Peter Mombaerts
2016-10-01

Prolyl hydroxylase domain enzymes and their role in cell signaling and cancer metabolism

Raúl Durán
2016-09-15

Cold sensitivity of TRPA1 is unveiled by the prolyl hydroxylation blockade-induced sensitization to ROS

Takahito Miyake, Tomohiro Numata, Nobuaki Takahashi, Hisashi Shirakawa, Shuji Kaneko
2016-09-09

TRPV3 in Drug Development

Dominic L Li
2016-07-14

Modulation of TRPV4 by diverse mechanisms

Sara Baratchi, Peter McIntyre
2016-04-15

TRP functions in the broncho-pulmonary system

Francesco De Logu
2016-03-04

Sensing of redox status by TRP channels
2016-02-03

Role of TRP ion channels in cancer and tumorigenesis

George Shapovalov, Prevarskaya NB
2016-01-11

Pharmacological targeting of the HIF hydroxylases--A new field in medicine development

Christopher Joseph Schofield, Peter J. Ratcliffe, Mun Chiang Chan, James P Holt-Martyn
2016-01-13

Proton-gated Ca(2+)-permeable TRP channels damage myelin in conditions mimicking ischaemia
2016-01-01

FIH Regulates Cellular Metabolism through Hydroxylation of the Deubiquitinase OTUB1

Carsten C Scholz, Javier Rodríguez, Christina Pickel, Stephen P Burr, Karen A Nolan, Miguel Cavadas, Doug N Halligan, James A Nathan, Daniel J Peet, Alex von Kriegsheim, Eoin P Cummins, Cormac T Taylor, Bianca Crifo
2015-11-13

Beyond ion-conduction: Channel-dependent and -independent roles of TRP channels during development and tissue homeostasis

Kees Jalink
2015-09-24

Potential therapeutic value of TRPV1 and TRPA1 in diabetes mellitus and obesity
2015-09-15

TRPs and pain
2015-03-16

Activation of transient receptor potential vanilloid 3 channel suppresses adipogenesis

Yu Huang, Hiu Yee Kwan
2015-06-01

Novel insights into TRPM7 function in fibrotic diseases: a potential therapeutic target
2015-11-01

Monosodium iodoacetate-induced inflammation and joint pain are reduced in TRPA1 deficient mice--potential role of TRPA1 in osteoarthritis

Mari Hämäläinen, Elina Nummenmaa, Pinja Ilmarinen, Katriina Vuolteenaho, Lauri Lehtimäki
2014-11-20

Oxygen-dependent hydroxylation by FIH regulates the TRPV3 ion channel

Chris Peers, Jason L Scragg, Wai Li Lim, Mark Dallas, Daniel J Peet, Grigori Y Rychkov, Jonathan M Gleadle
2014-01-01

Thermally activated TRPV3 channels
2014-01-01

TRPA1 channels: chemical and temperature sensitivity

Sviatoslav N Bagriantsev, Elena O Gracheva
2014-05-01

The Role of Hypoxia-Inducible Factor in Wound Healing

Dominik Duscher, Michael T Longaker, Geoffrey C Gurtner
2014-04-08

Post-Translational Modifications of TRP Channels

Armin Huber
2014-04-02

TRPA1 mediates bladder hyperalgesia in a mouse model of cystitis

Jennifer J Deberry, Brian M. Davis
2014-01-01

The TRPA1 channel in inflammatory and neuropathic pain and migraine
2014-05-01

Transient receptor potential (TRP) channels: a clinical perspective
2014-10-28

The thermosensitive TRPV3 channel contributes to rapid wound healing in oral epithelia

Makiko Kashio
2013-04-19

Factor inhibiting HIF-1 (FIH-1) modulates protein interactions of apoptosis-stimulating p53 binding protein 2 (ASPP2).

Heimo Mairbäurl
2013-12-12

The hypoxic ventilatory response and TRPA1 antagonism in conscious mice.

Kotaro Takeda
2012-08

Screening chelating inhibitors of HIF-prolyl hydroxylase domain 2 (PHD2) and factor inhibiting HIF (FIH)
2011-12-19

Heteromeric heat-sensitive transient receptor potential channels exhibit distinct temperature and chemical response
2011-08-28

TRPA1 underlies a sensing mechanism for O2.

Nobuaki Takahashi, Peter Carmeliet
2011-02-23

Factor-inhibiting hypoxia-inducible factor (FIH) catalyses the post-translational hydroxylation of histidinyl residues within ankyrin repeat domains

Rasheduzzaman Chowdhury, Christopher Joseph Schofield, Refaat B. Hamed, Michael A McDonough, Benedikt M Kessler, M E Cockman, Peter J. Ratcliffe, Timothy D W Claridge

Artike - wd:Q36323671

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